We need you in the fight against childhood cancer.
The COVID-19 pandemic caused the temporary closure of university labs, disrupting childhood cancer research. It also led to the cancellation of fundraising events, impacting ALSF's ability to fund research grants. COVID-19 put research on hold, but for children with cancer, time is priceless.
The Childhood Cancer Innovation Circle (CCIC) is an exclusive membership circle for monthly donors who give $1,000 or more each month. These sustaining gifts will be designated to ALSF's Innovation Grants, which provide critical funding to experienced investigators with a novel approach to finding causes and cures for childhood cancer. This promising research can help scientists understand the cause of childhood cancers and develop more effective treatments.
Begin your monthly donation today to lead the movement to cure childhood cancer.
Childhood Cancer Innovation Circle gifts at Alex’s Lemonade Stand Foundation begin at $1,000.
Please contact Lexi Gratton at [email protected] to learn more.
After a relapse, Zach's family was watching him deteriorate. His doctors were running out of options. Days after starting a clinical trail made possible by ALSF-funded research, Zach was running down the hall to play.
Your monthly gift will fuel the innovative research that saves lives.
Innovation Grant Spotlight
Dr. Costas Lyssiotis, University of Michigan
2019 Innovation Grantee
Therapeutic Targeting of the Disrupted Metabolic State in DIPG
Dr. Lyssiotis is studying the molecular foundations that lead to the profound sensitivity of DIPG cells to ferroptosis (a type of cell death) by evaluating the anti- tumor activity of ferroptosis in human patient-derived DIPG tumor models. Unlike cancer cells, normal cells readily tolerate inhibition of many of the nodes that promote ferroptosis in DIPG cells. This suggests that a therapeutic window may exist by targeting these pathways. Results from this research will uncover novel targets for DIPG therapy and evaluate ferroptosis as a treatment regimen that can proceed to clinical trials for DIPG patients.
Members will receive exclusive benefits as a thank you for their generous investment in childhood cancer research. These benefits include:
- Annual impact report on progress of Innovation Grant-funded projects
- Behind-the-scenes look at childhood cancer through members-only quarterly emails
- Invitation to ALSF events
- Give on your terms – Manage your account easily online to change, pause, or cancel your gift at any time
- Spread your donation throughout the year to help you strategize your charitable giving