ALSF Childhood Cancer Research Grants
With your support, we have been able to fund outstanding research, leading toward cures and improved quality of life for children with cancer. Browse through more than 1,500 funded projects below.
Use the search tool to refine your results. You can also click on a heading to sort by project title, institution name, or year the grant was awarded. Click on the project title to read more information.
You can learn about ALSF's grant review process here.
ALSF Funded Research Projects
Project Title | Institution / Principal Investigator(s) | Grant Type | Year | State |
---|---|---|---|---|
Discovery of New Targets and Pathways for T-ALL Therapy | Dana-Farber Cancer Institute / Thomas Look | Bridge Grants | 2012 | Massachusetts |
The role of NOTCH1 in T-cell acute lymphoblastic leukemia. | Columbia University Medical Center / Adolfo Ferrando | Bridge Grants | 2012 | New York |
Mechanisms of PPM1D in Medulloblastoma Tumorigenesis and Invasion | Emory University / Robert Craig Castellino, MD | Bridge Grants | 2012 | Georgia |
Targeting the ETS Transcription Factor Rearrangement EWS/FLI in Ewing sarcoma | Dana-Farber Cancer Institute / Kimberly Stegmaier, MD | Bridge Grants | 2012 | Massachusetts |
Cooperating Genes for inv16 Acute Myeloid Leukemia | University of Massachusetts Medical School / Lucio Castilla | Bridge Grants | 2012 | Massachusetts |
Improving Thymus Function by RB Inactivation | Lucile Packard Children’s Hospital at Stanford University School of Medicine / Julien Sage, PhD | Springboard Grants | 2012 | California |
Pediatric Developmental Therapeutics Center of Excellence at UCSF | University of California San Francisco / Katherine Matthay, MD, Kieuhoa Vo, MD, - Scholars: Amit Sabnis, MD, Lena Winestone, MD/MSHP, Beth Winger, MD/PhD, Bo Qiu, MD/PhD | Center of Excellence Grants | 2012 | California |
Texas Children's Cancer Center Alex's Lemonade Stand Center of Excellence | Baylor College of Medicine / Stacey Berg, MD - Scholars: Holly Lindsay, MD/MS, Sarah Injac, MD | Center of Excellence Grants | 2012 | Texas |
Dana-Farber/Children’s Hospital Cancer Center Developmental Therapeutics Center of Excellence | Dana-Farber Cancer Institute / Steven DuBois, MD & Wendy London, PhD - Scholars: Melissa Burns, MD; Kevin Campbell, MD; Natalie Collins, MD/PhD; David Shulman, MD | Center of Excellence Grants | 2012 | Massachusetts |
Prognostic and Therapeutic Significance of Stem Cell Heterogeneity in AML | Fred Hutchinson Cancer Research Center / Roland Walter, MD, PhD | 'A' Award Grants | 2012 | Washington |
Epigenetic Modifiers as Therapeutic Targets in Pediatric T-cell Acute Lymphoblastic Leukemia | Washington University / Grant Challen, PhD | 'A' Award Grants | 2012 | Missouri |
BET Bromodomain Inhibition as Epigenetic Therapy in Pediatric Leukemia | Cold Spring Harbor Laboratory / Christopher Vakoc, MD, PhD | 'A' Award Grants | 2012 | New York |
A Role for Notch in Self-renewal in Embryonal Rhabdomyosarcoma | Massachusetts General Hospital / Myron Ignatius, PhD | 'A' Award Grants | 2012 | Massachusetts |
Comprehensive Analysis of Risk Factors for Pediatric Cancers Using the Utah Population Database | Huntsman Cancer Institute / Joshua Schiffman, MD | Epidemiology Grants | 2012 | Utah |
Childhood Leukemia in Kenya Identified Through Malaria Slide Review | Indiana University / Terry Vik | Epidemiology Grants | 2012 | Indiana |
Neurofibromatosis Type 1 as a model population for pediatric brain cancer prevention and control research | Washington University / Kimberly Johnson Ph.D. | Epidemiology Grants | 2012 | Missouri |
Targeting Neovascularization in Graft-Versus-Host Disease | Memorial Sloan-Kettering Cancer Center / Marcel van den Brink, MD/PhD | Innovation Grants | 2012 | New York |
Identification of predisposition genes for Ewing sarcoma segregating in high-risk pedigrees | Huntsman Cancer Institute / Lisa Cannon-Albright, PhD | Innovation Grants | 2012 | Utah |
V alpha-invariant NKT cells as a novel platform for cancer immunotherapy | Baylor College of Medicine / Leonid Metelitsa, MD, PhD | Innovation Grants | 2012 | Texas |
Developing Immune-modulatory Strategies Against Primary and Metastatic Tumors in the Central Nervous System | Case Western Reserve University / Alex Huang, MD, PhD | Innovation Grants | 2012 | Ohio |
Development of the Next Generation FLT3 Inhibitors for Pediatric AML and Infant ALL | The Johns Hopkins University School of Medicine / Donald Small, MD, PhD | Innovation Grants | 2012 | Maryland |
Modeling Pediatric Leukemia in the Zebrafish to Enable Discovery of New Anti-Leukemic Compounds | University of California, San Diego / David Traver, MD | Innovation Grants | 2012 | California |
A novel mouse model of rhabdomyosarcoma | Vanderbilt University Medical Center / Chin Chiang, PhD | Innovation Grants | 2012 | Tennessee |
Mechanisms of LYL1-associated T-ALL development | Baylor College of Medicine / Margaret Goodell, PhD | Innovation Grants | 2012 | Texas |
Searching for genetic vulnerabilities in osteosarcoma through genome-wide RNAi screening | Dana-Farber Cancer Institute / Stuart Orkin, MD | Innovation Grants | 2012 | Massachusetts |
In-UTR mutations in neuroblastoma: Functional consequences and therapeutic implications | Children’s Hospital of Philadelphia / Andrei Thomas-Tikhonenko, PhD | Innovation Grants | 2012 | Pennsylvania |
Identification and validation of new therapeutic targets in pediatric leukemia through an aneuploidy-based synthetic lethality screen | Dana-Farber Cancer Institute / David Pellman, MD | Innovation Grants | 2012 | Massachusetts |
Casein Kinase 1 alpha Agonists as Novel Medulloblastoma Inhibitors | University of Miami Miller School of Medicine / David Robbins, PhD | Innovation Grants | 2012 | Florida |
Novel STAT3 drug development for childhood osteosarcoma therapy using drug repositioning | Research Institute at Nationwide Children's Hospital / Jiayuh Lin, PhD | Innovation Grants | 2012 | Ohio |
The role of vitamin D in hepatoblastoma formation and prevention | Brigham and Women's Hospital / Wolfram Goessling, MD/PhD | Innovation Grants | 2012 | Massachusetts |
Transcriptome Sequencing (RNA-Seq) for Identification of Novel Markers of Disease Outcome and Therapeutic Targets in Acute Myeloid Leukemia | Fred Hutchinson Cancer Research Center / Fabiana Ostronoff, MD | Young Investigator Grants | 2012 | Washington |
Small-molecule screening for novel pediatric glioma radiosensitizers. | Yale School of Medicine / Ranjit Bindra | Young Investigator Grants | 2012 | Connecticut |
Determinants of Testicular Germ Cell Tumor Platinum Sensitivity and Resistance | University of California, San Diego / Paolo Abada | Young Investigator Grants | 2012 | California |
Screening for New Rhabdomyosaroma Pathogenesis Genes in a Drosophila Model | University of Texas Southwestern Medical Center / Kathleen Galindo | Young Investigator Grants | 2012 | Texas |
Selective inhibition of nuclear export as a novel therapeutic strategy in AML | Dana-Farber Cancer Institute / Julia Etchin | Young Investigator Grants | 2012 | Massachusetts |
Role of Myosin VI in Pediatric Glioma Proliferation and Invasion | University of Pennsylvania / Monalisa Mukherjea | Young Investigator Grants | 2012 | Pennsylvania |
Identifying Therapeutic Targets for MiT Associated Pediatric Cancers | Yale School of Medicine / Sean Landrette | Young Investigator Grants | 2012 | Connecticut |
Adoptive Cell Therapy Targeting Antigen Escape Variants in Childhood High Grade Glioma | Baylor College of Medicine / Meenakshi Hegde | Young Investigator Grants | 2012 | Texas |
Epigenetic regulation of self-renewal pathways in hematopoietic and leukemic stem cells | George Washington University / Alexandros Tzatsos, MD/PhD | Young Investigator Grants | 2012 | District of Columbia |
Investigating the Role of the RNA Binding Protein LIN28 in Neuroblastoma | Boston Children’s Hospital / John Powers | Young Investigator Grants | 2012 | Massachusetts |
Exploiting WT1 Genomic Alterations for Target Identification and MRD Monitoring in Pediatric AML | Fred Hutchinson Cancer Research Center / Phoenix Ho | Young Investigator Grants | 2012 | Washington |
Development of Targeted Therapies in High Risk Childhood Acute Lymphoblastic Leukemia | Children’s Hospital of Philadelphia / Sarah Tasian | Young Investigator Grants | 2012 | Pennsylvania |
Development of An Innovative Treatment Strategy for Neuroblastoma and Other Pediatric Tumors: A Novel Phospholipid Ester Analogue and its Multifunctional Cancer-targeting Nanoconstruct | University of Wisconsin - Madison / Mario Otto | Young Investigator Grants | 2012 | Wisconsin |
Treatment for human hepatoblastoma based on recombinant adeno-associated virus vectors | University of Florida / Chen Ling | Young Investigator Grants | 2012 | Florida |
SWI/SNF Complex and Glucocorticoid Resistance in Pediatric Acute Lymphoblastic Leukemia | Dana-Farber Cancer Institute / Jennifer Wu | Young Investigator Grants | 2012 | Massachusetts |
Effects of CNS Treatment on Antioxidant Level, Apoptosis and Cognitive Abilities in Childhood Leukemia | University of Arizona / Ki Moore, R.N./Ph.D. | Nurse Researcher Grants | 2012 | Arizona |
Assessing the Relationship Between Physical Activity, Fatigue and Health Related Quality of Life in Children Receiving Cancer Treatment | Children’s Hospital of Philadelphia / Pattianne Belfield, PNP, CRNP | Nurse Researcher Grants | 2012 | Pennsylvania |
Childhood Cancer Survivor Utilization and Barriers to Primary Care Providers | Research Institute at Nationwide Children's Hospital / Micah Skeens, PNP | Nurse Researcher Grants | 2012 | Ohio |
Child and Adolescent Preferences for Involvement in their Cancer Treatment Decisions | Children’s Research Institute / Katherine Kelly, Ph.D. | Nurse Researcher Grants | 2012 | District of Columbia |