Mutagenesis and disease progression in RUNX1 mutant blood stem cells is caused by inflammation-induced hyperactive signaling and supraphysiological mitochondrial ROS |
St. Jude Children’s Research Hospital / Dirk Loeffler, PhD |
RUNX1 Early Career Investigator Grants |
2023 |
Tennessee |
Novel Resilience Genes Required for Cerebellum Development and Medulloblastoma Survival |
University of California San Francisco / Stephen Fancy, PhD, DVM |
Innovation Grants |
2023 |
California |
Pre-Targeted Radioimmunotherapy for Desmoplastic Small Round Cell Tumors |
Memorial Sloan-Kettering Cancer Center / Madelyn Espinosa-Cotton, PhD |
Young Investigator Grants |
2023 |
New York |
Radiation and the Tumor Microenvironment in an Immunocompetent Model of Ewing Sarcoma |
Children’s Hospital of Pittsburgh Foundation / Jessica Daley, MD |
Young Investigator Grants |
2023 |
Pennsylvania |
Reversing Feedback Immunosuppression during Oncolytic Virotherapy of Pediatric High Grade Glioma |
Augusta University Research Institute, Inc. / Bangxing Hong, PhD |
Reach Grants |
2023 |
Georgia |
Stapled Oncolytic Peptides for Treatment-Resistant Pediatric Leukemias |
Dana-Farber Cancer Institute / Loren Walensky, MD, PhD |
Innovation Grants |
2023 |
Massachusetts |
Structure-guided de novo design of molecules that selectively target EWS-FLI1 |
University of Texas Health Science Center at San Antonio / David Libich, PhD |
Innovation Grants |
2023 |
Texas |
Synthetic gene expression regulator switches (SynGERS) expressed in CAR T cells to cure children with solid tumors |
Baylor College of Medicine / Andras Heczey, MD |
R Accelerated Award Grants |
2023 |
Texas |
Synthetic Gene Expression Regulatory Switches (SynGERS) for Improved CAR T Cell Function in Pediatric Solid Tumors |
Baylor College of Medicine / Leidy Diana Caraballo Galva, PhD |
Young Investigator Grants |
2023 |
Texas |
Targeting Chromatin Remodeling Complexes for Rhabdomyosarcoma (RMS) Therapy |
Dana-Farber Cancer Institute / Jun Qi, PhD |
Innovation Grants |
2023 |
Massachusetts |