With your support, we have been able to fund outstanding research, leading toward cures and improved quality of life for children with cancer. Browse through more than 1,000 funded projects below.
Use the search tool to refine your results. You can also click on a heading to sort by project title, institution name, or year the grant was awarded. Click on the project title to read more information.
ALSF Funded Research Projects
|Project Title||Institution / Principal Investigator(s)||Grant Type||Year||State|
|The use of hematopoietic stem and progenitor cells to reverse treatment resistance to PD-1 blockade||University of Florida / Catherine Flores, PhD||Innovation Grants||2019||Florida|
|Identify Novel Druggable Targets to Treat Philadelphia chromosome-like B-Acute Lymphoblastic Leukemia||Children's Hospital of Philadelphia / Wei Tong, PhD & Junwei Shi, PhD||Innovation Grants||2019||Pennsylvania|
|Using Splice Switching Oligonucleotides (SSOs) to target MDM2 for rhabdomyosarcoma therapy||Research Institute at Nationwide Children's Hospital / Dawn Chandler, PhD||Innovation Grants||2019||Ohio|
|Targeting mechanisms of Siglec15-mediated immune evasion in hematologic malignancies||Emory University / Christopher Porter, MD, Curtis Henry, MD & Christopher Flowers, MD||Innovation Grants||2019||Georgia|
|The anti-tumor immune microenvironment in the Sonic Hedgehog subclass of medulloblastoma||Emory University / Anna Kenney, PhD & Dolores Hambardzumyan, PhD||Innovation Grants||2019||Georgia|
|Therapeutic Targeting of the Disrupted Metabolic State in DIPG||The Regents of the University of Michigan / Costas Lyssiotis, PhD & Sriram Venneti, PhD||Innovation Grants||2019||Michigan|
|Norepinephrine Transporter-Targeted Pharmacotherapy of Aggressive Neuroblastoma||Children's Hospital of Philadelphia / Michael Chorny, PhD, Garrett M. Brodeur, PhD & Ivan S. Alferiev, PhD||Innovation Grants||2019||Pennsylvania|
|Targeting microenvironment-induced TGFB signaling to overcome drug resistance in acute lymphoblastic leukemia||St. Jude Children's Research Hospital / Charles Mullighan, MD/PhD, Hiroki Yoshihara, MD/PhD & Chunxu Qu, PhD||Innovation Grants||2019||Tennessee|
|Novel Therapy of Heterogeneous B-cell Acute Lymphocytic Leukemia by Targeting Convergent Oncogenic Mediators STATs||University of Alberta / Hasan Uludag, PhD, Joseph Brandwein, PhD & Xiaoyan Jiang, MD/PhD||Innovation Grants||2019||Alberta|
|Pediatric Osteosarcoma: Identifying the elusive molecular signature and its relationship to this disease||St. Jude Children's Research Hospital / Linda Hendershot, PhD||Innovation Grants||2019||Tennessee|