ALSF Childhood Cancer Research Grants
With your support, we have been able to fund outstanding research, leading toward cures and improved quality of life for children with cancer. Browse through more than 1,500 funded projects below.
Use the search tool to refine your results. You can also click on a heading to sort by project title, institution name, or year the grant was awarded. Click on the project title to read more information.
You can learn about ALSF's grant review process here.
ALSF Funded Research Projects
| Project Title |
Institution / Principal Investigator(s) |
Grant Type | Year | State |
|---|---|---|---|---|
| Characterization of the Role of Chromosome 1p Deletion in MYCN-Amplified Neuroblastoma | University of California San Francisco / Miller Huang, PhD | Young Investigator Grants | 2013 | California |
| Engager T cells for the Adoptive Immunotherapy of Pediatric Malignancies | Baylor College of Medicine / Stephen Gottschalk, MD | Innovation Grants | 2013 | Texas |
| Dissecting and Targeting the Wnt Signaling Pathway in Metastatic Osteosarcoma | Baylor College of Medicine / Jason T. Yustein, MD, PhD | Young Investigator Grants | 2013 | Texas |
| Multispecific T Cells for Adoptive Immunotherapy of Pediatric High Grade Glioma (HGG) | Baylor College of Medicine / Nabil Ahmed, MD, MSc | Innovation Grants | 2013 | Texas |
| Combining Oncolytic Vaccinia Virus with GD2.CAR-modified Vaccinia Virus-specific T-cells for the Treatment of Relapsed Neuroblastoma and Sarcoma | Baylor College of Medicine / Cliona Rooney, PhD | Reach Grants | 2013 | Texas |
| Immunotherapy for Pediatric Atypical Teratoid/Rhabdoid Tumor | Baylor College of Medicine / William Decker, PhD | Reach Grants | 2013 | Texas |
| The Phase I/II Trials Collaborative for Children, Adolescents, and Young Adults at UH Rainbow Babies & Children's Hospital and the Case Comprehensive Cancer Center | Case Western Reserve University / Letterio, John MD & Matloub, Yousif MD | Phase I/II Infrastructure Grants | 2013 | Ohio |
| An Intersection of Cell Metabolism and Differentiation in Childhood Sarcomas | Cedars-Sinai Medical Center / Sandra Orsulic, PhD | Innovation Grants | 2013 | California |
| Children's Hospital Colorado Experimental Therapeutics Program | Children’s Hospital Colorado / Lia Gore, MD | Phase I/II Infrastructure Grants | 2013 | Colorado |
| Nationwide Children's Hospital Phase I/II Infrastructure | Research Institute at Nationwide Children's Hospital / Sarah O'Brien, MD and Timothy Cripe, MD, PhD | Phase I/II Infrastructure Grants | 2013 | Ohio |
| Therapeutic Targeting of LARG-RhoA Signaling Axis in Childhood Leukemia | Cincinnati Children's Hospital Medical Center / Yi Zheng, PhD | Innovation Grants | 2013 | Ohio |
| Columbia University Developmental Therapeutics Program: Striving for Excellence | Columbia University / Julia Glade Bender, MD | Phase I/II Infrastructure Grants | 2013 | New York |
| Therapeutically Targeting a Tumor Suppressor Complex in Aggressive Pediatric Cancers | Dana-Farber Cancer Institute / Charles Roberts, MD, PhD | Innovation Grants | 2013 | Massachusetts |
| Histone Modification and Hmgn1 Overexpression as Drivers of B-ALL with Polysomy 21 | Dana-Farber Cancer Institute / Andrew Lane, MD, PhD | Young Investigator Grants | 2013 | Massachusetts |
| Reactivating Apoptosis in Refractory Pediatric Cancer by Molecular Inhibition of MCL-1 | Dana-Farber Cancer Institute / Loren Walensky, MD, PhD | Innovation Grants | 2013 | Massachusetts |
| The Role of Prmt1 in Osteosarcoma Initiation and Metastasis | Dana-Farber Cancer Institute / Hao-Ru Hsu, PhD | Young Investigator Grants | 2013 | Massachusetts |
| Therapeutic Potential of the MST1/Hippo Tumor Suppressor Pathway in Alveolar Rhabdomyosarcoma | Duke University / Corinne Mary Linardic, MD, PhD | Innovation Grants | 2013 | North Carolina |
| Genomic Alterations in ETV6 Predict Outcome in Pediatric AML | Fred Hutchinson Cancer Research Center / Heather Helton, MD | Young Investigator Grants | 2013 | Washington |
| PainSquad+: A Smartphone App to Support Real-Time Pain Management for Adolescents with Cancer | Hospital for Sick Children / Jennifer Stinson, RN, PhD | Nurse Researcher Grants | 2013 | Ontario |
| Targeting Metabolism in Alveolar Soft Part Sarcomagenesis | Huntsman Cancer Institute / Kevin Jones, MD | 'A' Award Grants | 2013 | Utah |
| Reversing the Oncogenic Roles of Misdirected Chromatin Remodeling in Synovial Sarcoma | Lucile Packard Children’s Hospital at Stanford University School of Medicine / Cigall Kadoch, PhD | Young Investigator Grants | 2013 | California |
| Next-Generation Therapies for Hedgehog Pathway-Dependent Tumors | Lucile Packard Children’s Hospital at Stanford University School of Medicine / James Chen, PhD | Innovation Grants | 2013 | California |
| Oncogenic Hedgehog Pathway Activation by a Putative Rho GTPase-Activating Protein | Lucile Packard Children’s Hospital at Stanford University School of Medicine / Jun Ni, PhD | Young Investigator Grants | 2013 | California |
| Novel Therapeutic Targets in Relapse T-cell Acute Lymphoblastic Leukemia | Massachusetts General Hospital / David Langenau, PhD | Innovation Grants | 2013 | Massachusetts |
| Multifunctional Nanomaterials for the Prevention of Radiotherapy's Side Effects and Childhood Cancers | Massachusetts General Hospital / Charalambos Kaittanis, PhD | Young Investigator Grants | 2013 | Massachusetts |
| Novel Strategy for Reducing Radiation-Induced Morbidity and Treating Recurrent Medulloblasoma | Massachusetts General Hospital / Rakesh Jain, PhD | Reach Grants | 2013 | Massachusetts |
| PRL3 as a Novel Therapeutic Target for Relapsed T-cell Acute Lymphoblastic Leukemia | Massachusetts General Hospital / Jessica Blackburn, PhD | Young Investigator Grants | 2013 | Massachusetts |
| LRP1 and Angiogenesis in Pediatric Malignant Glioma | Mayo Clinic Jacksonville / Takahisa Kanekiyo, MD, PhD | Young Investigator Grants | 2013 | Florida |
| Rational Combination Therapy of AML | Memorial Sloan-Kettering Cancer Center / Alex Kentsis, MD, PhD | 'A' Award Grants | 2013 | New York |
| Epigenomics of High Risk Pediatric T Cell Leukemia | New York University School of Medicine / Iannis Aifantis, PhD | Reach Grants | 2013 | New York |
| An Oncolytic Herpes Simplex Virus Restricted in Entry to Neuroblastoma Cells | Northwestern University Medical School / Richard Longnecker, PhD | Innovation Grants | 2013 | Illinois |
| DICER1, MicroRNAs and Pediatric Cancer: An Emerging Story | Research Institute of the McGill University Health Centre / William Foulkes, MD, PhD | Innovation Grants | 2013 | Quebec |
| Accelerating Access to Cellular Therapies for the Treatment of Childhood Malignancies | Seattle Children’s Hospital and Regional Medical Center / Julie Park, MD | Phase I/II Infrastructure Grants | 2013 | Washington |
| Novel Targeted Therapies for Rhabdomyosarcoma | St. Jude Children’s Research Hospital / Michael Dyer, PhD | Innovation Grants | 2013 | Tennessee |
| Inflammatory Signaling in the Tumor Microenvironment | St. Jude Children’s Research Hospital / Peter J. Murray, PhD | Springboard Grants | 2013 | Tennessee |
| Genetic Profiling and Experimental Modeling of High-risk Acute Lymphoblastic Leukemia | St. Jude Children’s Research Hospital / Kathryn Roberts, PhD | Young Investigator Grants | 2013 | Tennessee |
| Modeling Genetic Modifiers of Down Syndrome Leukemogenesis | Children’s Hospital of Philadelphia / Stella T. Chou, MD | Springboard Grants | 2013 | Pennsylvania |
| Nanoparticle Delivery of Therapeutic Agents in Neuroblastomas | Children’s Hospital of Philadelphia / Garrett M. Brodeur, MD | Innovation Grants | 2013 | Pennsylvania |
| Clinical Epidemiology Studies in Children's Oncology Group Clinical Trials | Children’s Hospital of Philadelphia / Richard Aplenc, MD, PhD, MSCE | Epidemiology Grants | 2013 | Pennsylvania |
| Preclinical Development of Targeted Therapy for Neuroblastoma with ALK and CDK4/6 Dual Pathway Inhibition | Children’s Hospital of Philadelphia / Yael Mossé, MD | Reach Grants | 2013 | Pennsylvania |
| Defining the Mechanism by which LIN28B acts as an Oncogene in Neuroblastoma | Children’s Hospital of Philadelphia / Robert Schnepp, MD, PhD | Young Investigator Grants | 2013 | Pennsylvania |
| Epigenetic Characterization of the Neuroblastoma Driver Genes ARID1A and ARID1B | Children’s Hospital of Philadelphia / Michael Hogarty, MD | Innovation Grants | 2013 | Pennsylvania |
| Alex's Lemonade Stand Foundation Center of Excellence in Childhood Cancer Drug Development and Clinical Pharmacology at The Children's Hospital of Philadelphia | Children’s Hospital of Philadelphia / Frank Balis, MD - Scholar: Emily Blauel, MD | Center of Excellence Grants | 2013 | Pennsylvania |
| Targeting RNA Helicase DDX3 to Treat Recurrent High Grade Sarcoma | The Johns Hopkins University School of Medicine / David Loeb, MD, PhD | Reach Grants | 2013 | Maryland |
| Genetic Alterations in Intramedullary Spinal Cord Tumors | The Johns Hopkins University School of Medicine / George Jallo, MD | Innovation Grants | 2013 | Maryland |
| Epigenetic Regulation of T cell Activation and Immunotherapy | The Johns Hopkins University School of Medicine / Brian Ladle, MD, PhD | Young Investigator Grants | 2013 | Maryland |
| Development of a Novel Mer Tyrosine Kinase Inhibitor for Treatment of ALL | University of Colorado Denver / Doug Graham, MD, PhD | Reach Grants | 2013 | Colorado |
| Theranostics in Children and Young Adults | University of Iowa / Sue O'Dorisio, MD, PhD | Springboard Grants | 2013 | Iowa |
| Dissecting the Mechanism of Overgrowth and Tumorigenesis in Beckwith-Wiedemann Syndrome | University of Pennsylvania / Jennifer Kalish, MD, PhD | Young Investigator Grants | 2013 | Pennsylvania |
| Mechanisms Regulating Medulloblastoma Progression | University of Pennsylvania / Nadia Dahmane, PhD | Innovation Grants | 2013 | Pennsylvania |
| Children's Hospital of Pittsburgh of UPMC Phase 1-2 Infrastructure Support Grant | University of Pittsburgh / Jean Tersak, MD | Phase I/II Infrastructure Grants | 2013 | Pennsylvania |
| Function of the PR Domain of the MDSI-EVI1 in MLL Fusion Protein Leukemogenesis | University of Rochester / Archibald Perkins, MD, PhD | Springboard Grants | 2013 | New York |
| Pre-Clinical Testing of T cells Coded with CARs for DIPG | University of Texas / Laurence Cooper, MD, PhD | Innovation Grants | 2013 | Texas |
| Development of a Pharmacodynamic Marker of EWS-FLI1 Activity to Aid in the Clinical Translation of Targeted Therapies for Ewing sarcoma | Van Andel Research Institute / Patrick Grohar, MD, PhD | Reach Grants | 2013 | Michigan |
| Identification of Risk Factors for Pediatric Brain Tumors in a High Risk Population | Washington University / Kimberly Johnson, PhD, MPH | Epidemiology Grants | 2013 | Missouri |
| The Regulation of Hematopoietic Stem Cell Function by Granulocyte-Colony Stimulating Factor | Washington University / Laura Schuettpelz, MD, PhD | Young Investigator Grants | 2013 | Missouri |
| DNA Damage Responses Coordinate Survival and Cell Death Switching In Lymphocytes | Washington University / Jeffrey Bednarski, MD, PhD | 'A' Award Grants | 2013 | Missouri |
| Neural Stem Cell-Mediated Drug Delivery for Targeted Treatment of Medulloblastoma | Beckman Research Institute of City of Hope / Margarita Gutova, MD | Reach Grants | 2013 | California |
| Identification of TFAP4 (Transcription Factor AP-4/Activating Enhancer Binding Protein) as a Potential Master Regulator/Synthetic Lethal Gene of MYCN Amplified Neuroblastoma | Columbia University Medical Center / Darrell Yamashiro, MD, PhD | Innovation Grants | 2013 | New York |
| Dissecting the Hierarchy of Tumor Cell Differentiation Using Dual Recombinase Technology in a Novel Mouse Model of Rhabdomyosarcoma | Duke University Medical Center / David Van Mater, MD, PhD | Young Investigator Grants | 2013 | North Carolina |
| Stroma Biology Identifies Heparin as a Differentiating Agent in Neuroblastoma | Duke University Medical Center / Gerard Blobe, MD, PhD | Reach Grants | 2013 | North Carolina |
| Nitrosative Stress And Symptom Severity During Childhood Leukemia Treatment | Duke University Medical Center / Marilyn Hockenberry, RN, PhD | Nurse Researcher Grants | 2013 | North Carolina |
| IDO-based Immunotherapy for Pediatric Brain Tumors | Georgia Health Sciences University Research Institute, Inc. / Theodore Johnson, MD, PhD | 'A' Award Grants | 2013 | Georgia |
| The Role of PTPRD as a Tumor Suppressor in Neuroblastoma Pathogenesis | Mayo Clinic / Shizhen Zhu, MD, PhD | Young Investigator Grants | 2013 | Minnesota |
| Molecular Signature of Inflammation | Medical College of Wisconsin / Subramaniam Malarkannan, PhD | Springboard Grants | 2013 | Wisconsin |
| Moving EphB4 Therapeutics to Pediatric Phase I/II Trials | Oregon Health & Science University / Charles Keller, MD | Reach Grants | 2013 | Oregon |
| Evaluation of the Literacy Demand and Racial/Ethnic Influences for Self-Reported Symptomatic Adverse Events during Childhood Cancer Therapy | Palmetto Health / Janice Withycombe, PhD | Nurse Researcher Grants | 2013 | South Carolina |
| Targeted Inhibition of Signaling Networks in Pediatric Glioblastoma Stem Cells | University of California Berkeley / Erin Simonds, PhD | Young Investigator Grants | 2013 | California |
| Role of Fetal Growth in Pediatric Rhabdomyosarcoma | University of California Berkeley / Catherine Metayer, MD, PhD | Epidemiology Grants | 2013 | California |
| B-lapachone as a Novel Targeted Therapy for ATRTs and other Pediatric Cancers | University of Texas Southwestern Medical Center / James Amatruda, MD, PhD | Reach Grants | 2013 | Texas |
| Sexuality in Adolescents with Cancer | University of Calgary / Nancy Moules, PhD | Nurse Researcher Grants | 2013 | Alberta |
| Defining the Role of a Novel, Developmentally Restricted Hematopoietic Stem Cell in Pediatric Leukemias | University of California at Santa Cruz / Camilla Forsberg, PhD | Innovation Grants | 2013 | California |
| Develop a Therapeutic Vaccine Approach by Removing Viral Immune Evasion | University of California, Los Angeles / Ren Sun, PhD | Springboard Grants | 2013 | California |
| Engineering the Lymph Node Environment with Therapeutic Vaccine Depots to Combat Neuroblastoma | University of Maryland, College Park / Christopher Jewell, PhD | 'A' Award Grants | 2013 | Maryland |
| Arterial Stiffness in Children who Recently Completed Cancer Therapy | University of North Carolina / Sheila Santacroce, PhD | Nurse Researcher Grants | 2013 | North Carolina |
| Phase II Trial of Poly-ICLC in Pediatric Low Grade Gliomas | University of California, San Diego / Donald Durden, MD, PhD | Springboard Grants | 2013 | California |
| Genetic Dissection of Trisomy 21-TMD Using Human Pluripotent Stem Cells | Boston Children’s Hospital / Glenn MacLean | Young Investigator Grants | 2013 | Massachusetts |
| Investigating the Role of Circadian Rhythm in the Progression of Acute Myeloid Leukemia | Boston Children’s Hospital / Samantha Morris, PhD | Young Investigator Grants | 2013 | Massachusetts |
| Development of MicroRNA-Nanoparticles to Treat Childhood Acute Leukemia Carrying MLL Rearrangements | University of Cincinnati College of Medicine / Jianjun Chen, PhD | Innovation Grants | 2013 | Ohio |