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Children’s Hospital of Pittsburgh Foundation

4401 Penn Avenue
Central Plant, Floor 3
Pittsburgh, PA 15224
United States

Ewing sarcoma is an aggressive cancer usually diagnosed in teenagers. When this cancer advances and spreads to other parts of the body (metastasizes), it is very difficult to cure. Patients with metastatic Ewing sarcoma often receive radiation to help treat the cancer. During radiation therapy, the body?s immune system can help attack cancer cells. However, sometime this effect is suppressed. We are working to understand immune cell suppression during radiation with the hope that by reactivating the immune system, we can improve treatment response.