Childhood Cancer

Virtual Childhood Cancer Lecture Series

Alex’s Lemonade Stand Foundation (ALSF) presents The Virtual Childhood Cancer Lecture Series, featuring educational presentations by experts in the field. These free lectures will be of interest to scientists, especially those involved in childhood cancer research and to childhood cancer advocates. Each lecture will feature a 30-60 minute webinar which will include a Q&A period, with esteemed researchers, scientists, physicians and professors who will speak about an interesting topic.

If you have any questions about the lecture series, or if there is a topic you would like to hear about, please let us know by emailing [email protected]

Register for our upcoming free lectures:


Patient-Derived Laboratory Models of Childhood Cancer

Presented by: Patrick Reynolds, MD, PhD
Date: Wednesday, June 3, 2020
Time: 1pm (EST)

Lecture Details & Bio

After this lecture, participants will:

  • Understand what models are currently in the ALSF/COG repository and examples of studies that have been done with those models.
  • Learn about efforts to establish and characterize additional models.
  • Understand the advantages and disadvantages of various models and the potential for negative impact of poor model choice on experimental results.

Dr. Reynolds grew up in El Paso, TX, received his BA in Biology from The University of Texas at Austin, his MD from UT Southwestern Medical School in Dallas, TX, his PhD (Cell Biology) from UT Austin, and his pediatrics training at the National Naval Medical Center. His postdoctoral fellowship was in cancer immunology at UT Southwestern Medical School, Dallas, TX. He holds the rank of Commander, US Navy (retired). He is currently the Cancer Center Director for the School of Medicine, Texas Tech University Health Sciences Center, and is Director of the South Plains Oncology Consortium and the ALSF/COG Childhood Cancer Repository.


ALSF Childhood Cancer Lecture

Presented by: Jennifer Kalish, MD
Date: Friday, June 12, 2020
Time: 1 pm (EST)
Registration and more details coming soon


ALSF Childhood Cancer Lecture

Presented by: Matthew Hocking, PhD
Date: Friday, June 26, 2020
Time: 1 pm (EST)
Registration and more details coming soon

Watch previous lectures

Predisposition in Childhood Cancer

Presented by: Garrett Brodeur, MD
Date presented: May 1, 2020

View on YouTube

Lecture Details & Bio

After this lecture, participants will:

  • Know the features that identify a child/adolescent who is genetically disposed to get cancer (with or without a cancer at the time of evaluation).
  • Understand the importance of cancer surveillance in individuals who are genetically predisposed to get cancer.
  • Know the 5 most common cancers that occur in individuals with Li-Fraumeni syndrome under the age of 20.

Dr. Brodeur is the Director of the Cancer Predisposition Program at CHOP and Associate Director of the Abramson Cancer Center at Penn. He has a special interest in the molecular biology, genetics and targeted therapy of neuroblastoma. Dr. Brodeur is also a member of ALSF’s Scientific Advisory Board.


Precision Immunoncology for Childhood Cancers: It Starts with Optimal Targets

Presented by: John Maris, MD
Date Presented: Wednesday, May 13, 2020

View on YouTube

Lecture Details & Bio

After this lecture, participants will:

  • Understand strategies for immunotherapy target discovery and validation.
  • Understand what makes an “optimal” immunotherapeutic target.
  • Understand how one chooses an immunotherapeutic platform to move forward to preclinical and clinical development.

John Maris, MD is the Giulio D’Angio Professor of Pediatrics in the Perelman School of Medicine at the University of Pennsylvania and Children’s Hospital of Philadelphia. He is a physician-scientist who has focused for over three decades on the childhood cancer, neuroblastoma, with dual goals of improving patient outcomes and using the disease as a model to understand cancer in general. His group has discovered all known neuroblastoma susceptibility genes and has also identified many of the oncogenic drivers of the disease. Dr. Maris has steadfastly sought to translate these discoveries to the clinic using precision medicine approaches.


Pediatric Brain Cancers as Epigenetic Diseases

Presented by: Stephen C. Mack, PhD 
Date Presented: Wednesday, May 13, 2020

View on YouTube

Lecture Details & Bio

During this lecture, participants will:

  • Learn about the contribution of chromatin biology to pediatric brain tumorigenesis.
  • Understand therapeutic strategies in epigenetically altered cancers.
  • Learn about new technologies in mapping epigenetic landscapes of cancer.

Stephen C. Mack, PhD is an Assistant Professor at Texas Children's Hospital and Baylor College of Medicine. His team studies a variety of high-risk brain tumors to understand the role of deregulated epigenomes as drivers of cancer.


Zebrafish Modeling of Pediatric Sarcoma

Presented by: Genevieve Kendall, PhD
Date Presented: Friday, May 22, 2020

View on YouTube

Lecture Details & Bio

After this lecture, participants will:

  • Understand advances made in generating new animal models of fusion-oncogene driven pediatric sarcomas and their potential for therapeutic applications.
  • Summarize the value of applying zebrafish rhabdomyosarcoma models for drug discovery, functional genomics, and personalized medicine.
  • Understand how fusion-oncogenes co-opt developmental programs for tumorigenesis.

Genevieve C. Kendall, PhD, is a principal investigator in the Center for Childhood Cancer and Blood Diseases and an assistant professor in the Department of Pediatrics at The Ohio State University College of Medicine. Dr. Kendall received her bachelor’s degree in Cell and Molecular Biology at Texas Tech University where she was a Howard Hughes Medical Institute Undergraduate Research Fellow. She obtained her Ph.D. in Molecular Biology at the University of California, Los Angeles (UCLA), before performing her postdoctoral studies focused on pediatric oncology with Dr. James Amatruda at UT Southwestern Medical Center. Dr. Kendall’s research is focused on developing translational models of pediatric sarcomas that delineate the biology of the disease with the goal of identifying new therapeutic opportunities.


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