Cancer is one of the leading causes of death in human diseases. The main hypothesis underlying causes of human cancer suggests that important genes responsible for cell growth and survival are affected thus leading cells to grow without control. One important type of genes implicated in cancer development is called tumor suppressor genes (TSGs). Once affected (usually deleted or mutated), TSGs cause cells to undergo cellular changes leading to tumor formation. We recently reported that the WWOX gene is an important TSG.
