Alex's Lemonade Stand Foundation for Childhood Cancer

The Children's Oncology Group (COG) Cell Line and Xenograft Repository was created to establish, bank and distribute childhood cancer cell lines (cancer cells growing in test tubes) and patient-derived xenografts (PDX), which are tumors from patients grown directly in specialized mice. The pediatric cancer cell lines and PDXs from the repository enable investigators worldwide to better understand the biology and genomics of childhood cancers. They are especially important as laboratory models of childhood cancer for development and testing of new drugs prior to therapeutic clinical trials.