ALSF Childhood Cancer Research Grants
With your support, we have been able to fund outstanding research, leading toward cures and improved quality of life for children with cancer. Browse through more than 1,500 funded projects below.
Use the search tool to refine your results. You can also click on a heading to sort by project title, institution name, or year the grant was awarded. Click on the project title to read more information.
You can learn about ALSF's grant review process here.
ALSF Funded Research Projects
| Project Title | Institution / Principal Investigator(s) | Grant Type | Year | State |
|---|---|---|---|---|
| Targeting the immunosuppressive effects of Myc-hyperactivation in high-risk osteosarcoma | Emory University / Jason Yustein, MD/PhD | Innovation Grants | 2024 | Georgia |
| Development of allogeneic off-the-shelf gamma delta T cell product for pediatric AML | Baylor College of Medicine / Norihiro Watanabe, PhD | Innovation Grants | 2024 | Texas |
| The role of reactive gliosis in response to Immunotherapy in Diffuse Midline Glioma | University of Florida / Christina von Roemeling, PhD | Innovation Grants | 2024 | Florida |
| Targeting and imaging immunometabolic vulnerabilities in diffuse midline glioma | The Regents of the University of California San Francisco / Pavithra Viswanath, PhD | Innovation Grants | 2024 | California |
| DMG: From SWI/SNF’s role in cholesterol biosynthesis to new therapeutic opportunities | Board of Trustees of the Leland Stanford Junior University / Capucine Van Rechem, PhD | Innovation Grants | 2024 | California |
| RAF Dimer Inhibitor Treatment in Pediatric Acute Myeloid Leukemia | The Regents of the University of California San Francisco / Kevin Shannon, MD | Innovation Grants | 2024 | California |
| The role of tissue kallikrein 1 in hematopoietic stem cell transplant-associated thrombotic microangiopathy | Baylor College of Medicine / Sarah Sartain, MD | Innovation Grants | 2024 | Texas |
| Unraveling the Mechanisms of Inherited Predisposition to Childhood Leukemia | Boston Children’s Hospital / Vijay Sankaran, MD/PhD | Innovation Grants | 2024 | Massachusetts |
| Illuminating Choroid Plexus Carcinoma Vascularization in Real Time | Boston Children’s Hospital / Maria Lehtinen, PhD | Innovation Grants | 2024 | Massachusetts |
| Targeting of a putative unresolved wound healing process in childhood ependymoma | University of Colorado Denver / Nicholas Foreman, MD | Innovation Grants | 2024 | Colorado |
| Pathological Condensates and Transcription Dysregulation in Rhabdomyosarcoma at Single-Molecule Resolution | California Institute of Technology / Shasha Chong, PhD | Innovation Grants | 2024 | California |
| Development of CAR-T therapy for Ewing sarcoma using zebrafish in vivo models | Children’s Hospital Los Angeles / James Amatruda, MD/PhD | Innovation Grants | 2024 | California |
| Development of CAR-T therapy for Ewing sarcoma using zebrafish in vivo models | Children’s Hospital Los Angeles / James Amatruda, MD/PhD | Innovation Grants | 2024 | California |
| Direct targeting of oncoprotein assembly using mimetic peptide interference | Memorial Sloan-Kettering Cancer Center / Alex Kentsis, MD/PhD | Innovation Grants | 2024 | New York |
| Utilizing chromatin directed inhibitors to regulate gene expression in Ewing sarcoma for therapeutic benefit | University of North Carolina / Justin Sperlazza, MD/PhD | Young Investigator Grants | 2024 | North Carolina |
| MYCN-induced molecular clock disruption and metabolic rewiring drive neuroblastoma | Baylor College of Medicine / Lingzhi Li, PhD | Young Investigator Grants | 2024 | Texas |
| Improving homing and activity of CAR T cells in pediatric sarcomas | University of Colorado Denver / Joselyn Cruz Cruz, PhD | Young Investigator Grants | 2024 | Colorado |
| Vaccine-boosted CAR T cell therapy for high risk neuroblastoma | Children’s Hospital of Philadelphia / Timothy Spear, MD/PhD | Young Investigator Grants | 2024 | Pennsylvania |
| Capitalizing on functional genomics with targeted protein degradation in neuroblastoma | St. Jude Children’s Research Hospital / Ian Delahunty, PhD | Young Investigator Grants | 2024 | Tennessee |
| Defining how unique properties of the pediatric immune system contribute to poor efficacy of checkpoint blockade in children | Stanford University / Adrienne Long, MD/PhD | Young Investigator Grants | 2024 | California |
| In vivo transdermal generation of CD33 CAR T-cells towards acute myeloid leukemia | University of California, Los Angeles / Ruby Sims, PhD | Young Investigator Grants | 2024 | California |
| Modifying CAR T cell epigenetic programs to improve therapy against aggressive pediatric brain tumors | St. Jude Children’s Research Hospital / Meghan Ward, PhD | Young Investigator Grants | 2024 | Tennessee |
| Understanding the role of CDK8 in protein synthesis for treating MYC-driven medulloblastoma | University of Colorado Denver / Dong Wang, PhD | Young Investigator Grants | 2024 | Colorado |
| Unraveling GABAergic interneuron-like lineage in H3G34-mutant hemispheric high-grade gliomas: their impact on network formation and invasion | Dana-Farber Cancer Institute / Gustavo Alencastro Veiga Cruzeiro, PhD | Young Investigator Grants | 2024 | Massachusetts |
| Exploiting a Novel DNA Repair Defect in Ewing Sarcoma | Dana-Farber Cancer Institute / Shuhei Asada, MD/PhD | Young Investigator Grants | 2024 | Massachusetts |
| Novel mechanisms and therapeutic targeting of chemoresistant rhabdomyosarcoma | Massachusetts General Hospital / Yueyang Wang, PhD | Young Investigator Grants | 2024 | Massachusetts |
| Investigating the impact of osteosarcoma genetic lesions on bone differentiation | Dana-Farber Cancer Institute / James Morrow, MD/PhD | Young Investigator Grants | 2024 | Massachusetts |
| The influence of the raphe nucleus and serotonin on progression of diffuse intrinsic pontine glioma | Stanford University / Richard Drexler, MD/PhD | Young Investigator Grants | 2024 | California |
| Therapeutic targeting of clonal hematopoiesis in RUNX1 mutant FPDMM | University of Pennsylvania / Robert Bowman, Ph.D. | RARE Grant Program (Research Accelerating RUNX1 Exploration) | 2024 | Pennsylvania |