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Georgetown University

37 and O Street, NW
Washington, DC 20007
United States

Ewing's Sarcoma Family of Tumors (ES) are pediatric tumors of the bone and adjacent tissue. The over-all cure rate is 50-60% with significantly worse prognosis for patients who present with metastatic disease. In order to increase the number of patients who survive ES and to lessen the toxicity to those survivors, ES needs new therapy that goes beyond current chemotherapy. The current 'cytotoxic' therapy could be improved if medicines for ES were more precisely targeted to the ES cancer cells since this would spare the normal organs.

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