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University of California Berkeley

50 University Hall
Berkeley, CA 94720-7360
United States

Co-Investigators: Dr. Libby Morimoto & Dr. Robert Gunier

Background

Background: The cause of most childhood cancers remains a mystery. Even basic epidemiologic characteristics of children with cancer are not completely understood. Project Goal: This study seeks to describe where and when nearly every child with cancer in California for the last 30 years was born and diagnosed and to identify unusual patterns of disease occurrence and to ascertain if there are social disparities in childhood cancer. Methodology: Children with childhood cancers (25,518 cases) will be compared to healthy children (102,072 controls) drawn from the California Birth Cohort.

Background

Testicular cancers are the most common cancers in adolescents and young adults. New testicular cases have increased dramatically in the US over the past 40 years especially among Hispanic Americans. Environmental factors are probably responsible for much of the increase as changes in population genetics do not occur within such a short period.

Background


Pediatric RMS is the commonest soft tissue sarcoma in children. Despite improvements in therapy, a third or more die or experience recurrence within five years. Due largely to its rarity, the etiology of pediatric RMS remains poorly understood. Mounting evidence supports a key role of fetal growth characteristics in disease risk.