University of California, Davis Medical Center

University of California, Davis Medical Center

2315 Stockton Blvd

Sacramento, CA 95817

United States

Targeting Childhood Brain Cancer in a Dish to Catalyze New Therapies

This study examines H3.3, an attractive new target in the search for therapies specifically designed for pediatric gliomas.

Histone H3.3 Targeted Therapy for Pediatric High-grade Gliomas

Brain Tumors, Glioma, Medulloblastoma, Neuroblastoma

Background

High-grade pediatric gliomas are catastrophic cancers. Greater than 90% of children with these tumors die within two years of diagnosis even with today's best treatments, which are based on adult therapies and have devastating side effects. There is an urgent need for new, more effective therapies that are specifically designed for children because pediatric gliomas are different from adult.

Alex's Lemonade Stand Foundation for Childhood Cancer