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University of California, Davis Medical Center

2315 Stockton Blvd
Sacramento, CA 95817
United States

This study examines H3.3, an attractive new target in the search for therapies specifically designed for pediatric gliomas.

Background

High-grade pediatric gliomas are catastrophic cancers. Greater than 90% of children with these tumors die within two years of diagnosis even with today's best treatments, which are based on adult therapies and have devastating side effects. There is an urgent need for new, more effective therapies that are specifically designed for children because pediatric gliomas are different from adult.