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University of Utah

201 Presidents Cir
Salt Lake City, UT 84112
United States

Mentor Name: Michael Pulsipher

University of Utah

Pediatric glioblastoma multiforme (pGBM) (AKA pediatric hemispheric high-grade glioma) is a malignant (WHO grade IV) tumor. It accounts for about 3% of primary brain tumors in children in the United States. The median survival of children with GBM ranges from 13 to 20 months, with the vast majority succumbing to the disease. Despite extensive research, we know very little about which and how human neural cells regulate pGBM cell propagation in the brain.

Alveolar Soft Part Sarcoma (ASPS) is a rare, but deadly cancer of soft tissue (such as muscle, nerves, or fat) that primarily strikes adolescents and young adults. ASPS is caused by a mutation in which two different chromosomes mispair and fuse to make a new cancer-causing gene. Because ASPS grows slowly and painlessly, patients often don’t notice anything until the tumor has already metastasized, leaving few treatment options and a high likelihood of mortality within 5 years.

Mentor Name: Michael Pulsipher

Mentor Name: Kevin Jones

Background

Background

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