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Grant supports research on potential immunotherapy treatment for neuroblastoma

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Baylor College of Medicine News
12/30/2014

A Baylor College of Medicine and Texas Children’s Cancer Center researcher was one of three inaugural recipients of the Bio-therapeutics Impact Award from the nonprofit organization Alex’s Lemonade Stand.

Dr. Leonid Metelitsa, associate professor of pediatrics at Baylor, Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor, Texas Children’s Hospital and The Methodist Hospital and a member of the pediatric cancer program of the Dan L. Duncan Cancer Center at Baylor, received the $1.5 million, three-year grant for his research on a new form of cancer immunotherapy to treat neuroblastoma,  one of the most common solid tumors in children.

With support from the new Alex’s Lemonade Stand grant, he and his research and clinical colleagues will develop and clinically test natural killer T (NKT) cells that have been engineered to selectively target cancer cells in neuroblastoma patients. The research will include a Phase 1 clinical trial of the tumor-specific NKT cells in patients with resistant/recurrent neuroblastoma, which has a survival rate of less than 40 percent.

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