Mentor Name: Natasha Frederick

Germ cell tumors (GCTs) are rare tumors that occur in various locations including the brain. Intracranial GCTs (IGCTs) can be divided into germinomas and nongerminomatous germ cell tumors (NGGCTs) with NGGCTs further divided into five subtypes. IGCTs can be treated with various combinations of chemotherapy and radiotherapy with the germinomas having better response than NGGCTs. Because these tumors are found deep in the brain, obtaining a biopsy for diagnosis is very challenging and risky.