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Crazy 8 Grantee

Charles Mullighan, MBBS (Hons), MSc, MD

Charles Mullighan, MBBS (Hons), MSc, MD leads the Crazy 8 team that is studying small molecule degraders for targeting transcription factor drivers of childhood cancers.

Dr. Mullighan joined the Department of Pathology at St. Jude in 2008 and currently serves as the Deputy Director and co-leader of the Hematological Malignancies Program of the St. Jude Comprehensive Cancer Center. Dr. Mullighan holds the William E. Evans Endowed Chair He is also Medical Director of the St. Jude Biorepository. He has received numerous honors including an NCI R35 Outstanding Investigator Award in 2017, the American Society of Hematology William Dameshek Prize, and the Meyenburg Prize for Cancer Research. and in 2016, the inaugural St. Baldrick’s Foundation Robert J. Arceci Innovation Award.


I think the fundamental way that Alex’ s has made this possible is providing such a large mechanism of grant support. It’s allows us to take risks that may pay off.

Charles Mullighan, MBBS (Hons), MSc, MD