Northwestern Mutual Foundation

The mission of the Northwestern Mutual Foundation is to improve the lives of children and families in need. The Foundation has given more than $35 million since its inception in 1992 and is designed to create lasting impact in the communities where the company's employees and financial representatives live and work. We accomplish this by combining financial support, volunteerism, thought leadership and convening community partners to deliver the best outcomes. Our efforts are focused nationally on curing childhood cancer, and locally on education, neighborhoods and making our hometown of Milwaukee a great destination.

Visit Northwestern Mutual Foundation for more information

Co-Funded Projects

Project Title	Institutions	Co-Funder(s)
Epigenetic Targeting of Translation in Sarcomas	Seattle Children’s Hospital	Northwestern Mutual Foundation
Investigating interactions between the oncogenic phosphatase PPM1D and oncohistone H3K27M in diffuse midline gliomagenesis	Duke University	Northwestern Mutual Foundation
Targeting Fatty Acid Oxidation as a Metabolic Vulnerability in Pediatric Cancers	Dana-Farber Cancer Institute	Northwestern Mutual Foundation
Identifying mechanisms of revumenib resistance in KMT2A-r pediatric acute myeloid leukemia (AML)	The Johns Hopkins University School of Medicine	Northwestern Mutual Foundation
The immunosuppressive role of thrombospondin-2 in pulmonary metastatic osteosarcoma	Children’s Hospital Los Angeles	Northwestern Mutual Foundation
Targeting Chromatin Remodelers to Enhance Neuroblastoma Differentiation Therapy	Dana-Farber Cancer Institute	Northwestern Mutual Foundation
Elucidating Essential Kinase-Independent Functions of ALK	Children’s Hospital of Philadelphia	Northwestern Mutual Foundation
Novel Synergistic Drug Combinations for Lineage-plastic Pediatric Leukemias	The Johns Hopkins University School of Medicine	Northwestern Mutual Foundation
Social Determinants of Health Associated with Clinical Trial Enrollment in a Diverse Cohort of Children and Adolescents with Acute Lymphoblastic Leukemia	University of California, San Diego	Northwestern Mutual Foundation
Lipid nanoparticle delivery of CRISPR/Cas9 reagents for disruption of oncogenic translocations in alveolar rhabdomyosarcoma	University of California, Los Angeles	Northwestern Mutual Foundation

Project Title

Institutions

Co-Funder(s)

Epigenetic Targeting of Translation in Sarcomas

Seattle Children’s Hospital

Northwestern Mutual Foundation

Investigating interactions between the oncogenic phosphatase PPM1D and oncohistone H3K27M in diffuse midline gliomagenesis

Duke University

Northwestern Mutual Foundation

Targeting Fatty Acid Oxidation as a Metabolic Vulnerability in Pediatric Cancers

Dana-Farber Cancer Institute

Northwestern Mutual Foundation