Northwestern Mutual Foundation

The mission of the Northwestern Mutual Foundation is to improve the lives of children and families in need. The Foundation has given more than $35 million since its inception in 1992 and is designed to create lasting impact in the communities where the company's employees and financial representatives live and work. We accomplish this by combining financial support, volunteerism, thought leadership and convening community partners to deliver the best outcomes. Our efforts are focused nationally on curing childhood cancer, and locally on education, neighborhoods and making our hometown of Milwaukee a great destination.

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Co-Funded Projects

Project Title	Institutions	Co-Funder(s)
Next-Generation CAR-T Cell Immunotherapies for Pediatric Acute Myeloid Leukemia	Boston Children’s Hospital	Northwestern Mutual Foundation
Elucidating the tumor promoting roles of itaconate in ZFTA-RELA Fusion driven ependymomas	University of Michigan	Northwestern Mutual Foundation
Elucidating the role of MIF in the immunosuppressive tumor microenvironment of Ewing sarcoma	Children’s Hospital Los Angeles	Northwestern Mutual Foundation
A biophysical approach to improve CAR T cell efficacy against diffuse midline gliomas	St. Jude Children’s Research Hospital	Northwestern Mutual Foundation
Evaluating disease response using volumetric analysis vs 2D cross sectional analysis	University of Michigan	Northwestern Mutual Foundation
CAR-boosting vaccines for neuroblastoma	Children’s Hospital of Philadelphia	Northwestern Mutual Foundation
Regulation of medulloblastoma metastasis by the FOS transcription factor	Columbia University Medical Center	Northwestern Mutual Foundation
Testing a novel acylfulvene in malignant rhabdoid tumor	The Johns Hopkins University School of Medicine	Northwestern Mutual Foundation
IL7 signaling enhanced CAR T cells to treat pediatric solid tumors	Baylor College of Medicine	Northwestern Mutual Foundation
Incidence and grades of adverse events during treatment for pediatric acute lymphoblastic leukemia	Emory University	Northwestern Mutual Foundation

Project Title

Institutions

Co-Funder(s)

Next-Generation CAR-T Cell Immunotherapies for Pediatric Acute Myeloid Leukemia

Boston Children’s Hospital

Northwestern Mutual Foundation

Elucidating the tumor promoting roles of itaconate in ZFTA-RELA Fusion driven ependymomas

University of Michigan

Northwestern Mutual Foundation

Elucidating the role of MIF in the immunosuppressive tumor microenvironment of Ewing sarcoma

Children’s Hospital Los Angeles

Northwestern Mutual Foundation