Pediatric diffuse midline gliomas (DMGs) are highly aggressive brain tumors with a universally fatal prognosis, often taking the lives of children within a year of diagnosis. Despite extensive efforts, radiation therapy remains the only treatment that can extend survival, but tumor progression is inevitable. Recent advances in adult cancer research have revealed that a biological process called cellular senescence plays a significant role in how cancers develop, resist treatment, and recur.
Fighting childhood cancer, one cup at a time.
