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Hospital for Sick Children

555 University Avenue
Toronto, ON M5G1X8
Canada

Some childhood brain tumors can spread beyond the original tumor into the fluid surrounding the brain and spinal cord, called cerebrospinal fluid. This process, known as leptomeningeal metastasis, is one of the most serious complications of pediatric brain cancer. Once this spread occurs, treatment options are very limited, and survival is often measured in months. Current therapies, including radiation and chemotherapy, are not specifically designed to target this type of disease and can cause significant long-term side effects in children.

Hospital for Sick Children

 

Hospital for Sick Children

Medulloblastoma (MB) is the most common malignant brain tumor in children and a leading cause of cancer-related death. Despite aggressive treatments including surgery, chemotherapy, and radiation, many children experience lifelong neurological and cognitive impairments that profoundly affect their development and quality of life. Alarmingly, about 30 percent of patients relapse, and most cases of recurrence are fatal.

Hospital for Sick Children

Mentor Name: Uri Tabori

Hospital for Sick Children
Hospital for Sick Children

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