Developing new therapies for infants, children, adolescents and young adults with cancer requires a well-trained, dedicated multidisciplinary team. Physicians and scientists at The Children's Hospital of Philadelphia Division of Oncology and Center for Childhood Cancer Research are collaborating to develop new therapies for cancer. We are dedicated to improving our understanding of the biology and genomics of childhood cancer, developing better preclinical models, evaluating new drugs, and improving the efficiency and conduct of clinical trials.

Background

Despite the fact that cooperative group oncology trials have improved overall survival for children with cancer, investigators face significant challenges in conducting trials. This application seeks to develop novel data sets to improve the effectiveness of cooperative use trials by using administrative clinical data from approximately 100 hospital sites. Administrative clinical data contains an enormous wealth of information and its value has only recently begun to be realized in health-based research.