Mentor Name: John Maris

Understanding the impact of MYCN degradation on chemokine
secretion as a mechanism to induce an immune response and tumor remodeling will inform
drug development efforts about the biological significance of MYCN-targeting compounds.

Mentor Name: Jennifer Kalish

Mentor Name: Caitlin Elgarten

Mentor Name: Richard Aplenc

This project seeks to develop the data needed to define outcomes after relapse of pediatric acute myeloid leukemia. These data will be used as real world data to understand the optimal re-induction strategies for patients who AML relapses. The project focuses on manual chart abstraction to obtain these data from 14 centers across the United States. This data abstraction will be combined with advanced biostatistical and epidemiological analyses to determine the optimal therapy for children with relapse AML.

Mentor Name: Lisa Schwartz