Childhood Cancer

Childhood Leukemia

Chapter 3: Acute Lymphoblastic Leukemia

“Out of difficulties grow miracles.”

— Jean de la Bruyere

TREATMENT OF CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) is one of the major success stories of modern medicine. As recently as the 1960s, children with ALL usually lived only for a few months. Currently, 95% of children receiving optimal treatment attain remission, and the majority of those children are cured (defined as remaining in remission for at least five years after diagnosis).

This chapter covers risk factors for developing ALL, signs and symptoms, diagnosis, prognosis, and treatment. The treatment section is divided into five parts:

  • B-cell ALL
  • T-cell ALL
  • Philadelphia chromosome (Ph+) ALL
  • Infant ALL
  • Down syndrome and ALL

The chapter ends with ways to learn about the newest treatments available for childhood ALL.