ALSF Childhood Cancer Research Grants
With your support, we have been able to fund outstanding research, leading toward cures and improved quality of life for children with cancer. Browse through more than 1,500 funded projects below.
Use the search tool to refine your results. You can also click on a heading to sort by project title, institution name, or year the grant was awarded. Click on the project title to read more information.
You can learn about ALSF's grant review process here.
ALSF Funded Research Projects
Project Title | Institution / Principal Investigator(s) | Grant Type | Year | State |
---|---|---|---|---|
Small Molecule Inhibitors of ERG for Pediatric Leukemia and Sarcoma | University of Virginia, School of Medicine / John Bushweller, PhD | Innovation Grants | 2015 | Virginia |
Cure Osteosarcoma Lung Metastasis by Disrupting Tumor VCAM-1 Signaling with Macrophages | Case Western Reserve University / Alex Huang, MD, PhD | Innovation Grants | 2015 | Ohio |
Regulation of Tumor Debris Mediated Inflammation as a Therapeutic Modality in Medulloblastoma | Dana-Farber Cancer Institute / Mark Kieran, MD, PhD & Dipak Panigrahy, MD | Innovation Grants | 2015 | Massachusetts |
High-dimensional Biochemical CyTOF Analysis of Pediatric T cell Leukemias | University of California San Francisco / Jeroen Roose, PhD | Innovation Grants | 2015 | California |
Identifying Epigenetic Mechanisms Impacting Neuroblastoma Genome Stability and Drug Response | Massachusetts General Hospital / Johnathan Whetstine, PhD | Innovation Grants | 2015 | Massachusetts |
Identifying how Pre-existing Anti-Therapeutic Antibodies (PATA) are Associated with Better Outcome in a Clinical Trial of ADCC-inducing Anti-GD2 mAb | University of Wisconsin - Madison / Paul Sondel, MD, PhD | Innovation Grants | 2015 | Wisconsin |
Pharmacogenomics and Drug Screening Lead to a Novel Targeted Therapy with Potent and Specific Activity Against Mouse Models of MYCN-amplified Neuroblastoma | Virginia Commonwealth University / Anthony Faber, MD & Yael Mosse, MD (CHOP) | Innovation Grants | 2015 | Virginia |
Synergistic Differentiation Therapy in Neuroblastoma | Duke University / Gerard Blobe, M.D./Ph.D | Innovation Grants | 2015 | North Carolina |
Characterizing Resistance Mechanisms to BET-Bromodomain Inhibition in MYC-amplified | Broad Institute / Rameen Beroukhim, MD,PhD | Innovation Grants | 2015 | Massachusetts |
In Vivo Analysis of Early Neuroblastoma Development using Transgenic Quail | Stowers Institute for Medical Research / Paul Kulesa, PhD | Innovation Grants | 2015 | Missouri |
Identifying Mechanisms of Glucocorticoid Resistance in Pediatric Acute Lymphoblastic | University of Massachusetts Medical School / Michelle Kelliher, PhD | Innovation Grants | 2015 | Massachusetts |
Developing a Novel Tumor Model to Screen for New Therapies for Spinal Ependymoma | The Johns Hopkins University School of Medicine / Linda Resar, MD & Richard Schlegel, MD, PhD | Innovation Grants | 2015 | Maryland |
Optimizing Bispecific Antibody Therapy for Acute Leukemias | Fred Hutchinson Cancer Research Center / Roland Walter, MD, PhD & James Olson, MD, PhD | Innovation Grants | 2015 | Washington |
Antibody Targeted Natural Killer Cell-Derived Extracellular Vesicles for the Treatment of Childhood Acute Lymphoblastic Leukemia and Neuroblastoma | Children’s Hospital Los Angeles / Robert Seeger, MD & Alan Wayne, MD | Innovation Grants | 2015 | California |
Single Cell Analysis of Leukemia Initiation | Stanford University / Michael Cleary, MD | Innovation Grants | 2015 | California |
Enhancing Effectiveness of Immune Checkpoint Therapy in Neuroblastoma | Children’s Hospital Los Angeles / Shahab Asgharzadeh, MD | Innovation Grants | 2015 | California |
Histone H3.3 Targeted Therapy for Pediatric High-grade Gliomas | University of California, Davis Medical Center / Paul Knoepfler, PhD | Innovation Grants | 2015 | California |
Enhanced Drug Repurposing Screen in DSRCT Enabled by New In Vitro and In Vivo Models Based on CRISPR/Cas9 Genome Engineering | Memorial Sloan-Kettering Cancer Center / Marc Ladanyi, MD & Maria Jasin, PhD | Innovation Grants | 2015 | New York |
Integrative Genomic and Immunogenomic Analysis of Neuroblastoma | University of California at Santa Cruz / David Haussler, PhD | Innovation Grants | 2015 | California |
Functional Analysis and Therapeutic Targeting of STAG2 Mutations in Ewing sarcoma | Georgetown University / Todd Waldman, MD, PhD | Innovation Grants | 2015 | District of Columbia |
Preclinical Development of Atr Inhibitor VE-822, Delivered Systemically in Nanoparticles, for Medulloblastoma Therapy | University of North Carolina / Timothy Gershon, MD, PhD | Innovation Grants | 2015 | North Carolina |
Transcriptional Effectors of Activated RAS Signaling in Juvenile Myelomonocytic Leukemia | Boston Children’s Hospital / Alan Cantor, MD, PhD | Innovation Grants | 2015 | Massachusetts |