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Duke University Medical Center

2301 Erwin Road
Durham, NC 27710-0001
United States

Co-Investigator: Marika Horn, MSN, Baylor College of Medicine and Texas Children's Hospital

Background


Neuroblastoma is the most common cancer in infancy, with advanced-stage patients having a low survival rate. Patients with neuroblastoma cells that more closely resemble normal cells (i.e. differentiated) and with tumors with more connective tissue (i.e. stroma) have a better survival rate.

Background


An exploration of 'why' individual symptom differences occur is critical to understanding symptom experiences during childhood leukemia treatment; this will allow us to identify who may be most susceptible to treatment toxicities. This project explores why symptoms experienced in children with leukemia exhibit extreme variations in toxicity.

Duke University Medical Center

"Alex's Lemonade Stand Foundation truly understood that innovative ideas need to be translated from basic science to patients. It allows us to discover tumor markers that will be useful in clinics." - Hai Yan, MD

Poliovirus shows promise in treating glioblastoma

Photo, left: Dr. Linardic's lab. She is standing at the back, on the left.

Project Background