The Childhood Cancer Blog

The Childhood Cancer Blog

Welcome to The Childhood Cancer Blog
from Alex's Lemonade Stand Foundation!

To kick off 2023, Alex’s Lemonade Stand Foundation (ALSF) has funded six new childhood cancer projects for both early career and established researchers.  

ALSF is committed to changing the future of childhood cancer research by funding scientists and projects that will bring better treatments and cures to children with cancer. Attracting and retaining the best and brightest early career scientists is critical, as the funding at this stage will encourage and steer promising researchers toward long-term careers in pediatric oncology investigation. 

That’s why ALSF designed... Read More

What if a specific type of diet could magnify the impact of a targeted childhood cancer treatment? That’s the question Dr. Palaniraja Thandapani had after his initial findings that T-cell acute lymphoblastic leukemia (ALL) relied upon a specific amino acid, called valine, to grow. 

“That is an essential amino acid, and usually you acquire them from your food, it's not like your body can make them,” said Dr. Thandapani. “So that led to the idea that it can be targeted with the amount of availability of this amino acid in diet.”

This research was the genesis of Dr. Thandapani... Read More

Science to advance treatments for children with cancer has made incredible strides, but the causes of genetic mutations that lead to the development of cancer are still poorly understood. Alex’s Lemonade Stand Foundation (ALSF)-funded researcher Alex Kentsis, MD/PhD, of Memorial Sloan-Kettering Cancer Center in New York, and his lab are investigating those fundamental causes, to find cures for all childhood cancers. Recently, he’s made a breakthrough discovery about solid tumor development that has led to a clinical trial.

Cancer is driven by abnormal changes (also known as... Read More