Pediatric high-grade gliomas (pHGG) are very aggressive brain tumors with poor prognosis. Unfortunately, clinical trials in the last few decades have failed to produce treatments that work for this cancer. One of the reasons for the lack of good treatments is that not all cells in a tumor are equal, and current treatments are not able to kill the most important cells for pHGG. In fact, we now know that only some cells have the characteristics required to fuel tomorrow growth. We now have applied a technique that allows usto look at single cells in tumors.
