Childhood Cancer

Prognosis is an estimate of the chance for cure, but it is primarily used to determine treatment. Some infants with JMML can survive for years, but others need immediate treatment to survive. Your child’s doctors will consider all of the information obtained during the diagnostic process to determine a prognosis and treatment options (see the table below).


Factors that suggest a more favorable prognosis



Age at diagnosis

<3 years

Platelet count at diagnosis


Other conditions

Noonan syndrome with PTPN11

Hemoglobin F


Blasts in blood


Absolute neutrophil count (ANC)



Certain RAS or CBL mutations