Choriocarcinoma of the liver is a very rare tumor that is usually found in the first few months of an infant’s life. The baby might be anemic if the tumor has hemorrhaged. Clinical diagnosis can be made without biopsy based on MRI of the liver, extremely high serum β-hCG levels, and normal AFP levels for age.

Surgery usually follows chemotherapy because the tumors often hemorrhage. The combination of cisplatin, etoposide, and bleomycin has been effective in some children. After chemotherapy, the remaining tumor is surgically removed.