Phase I/II Infrastructure Grants

Doctors have identified a critical lack of funding for support personnel who speed up the process of enrolling children with cancer in clinical trials. With grants from Alex's Lemonade Stand Foundation, hospitals across the country have created new positions, specifically focused on filling this critical need, bringing the latest treatments to more children.

Please note that the Phase I/II Infrastructure grant is not offered every year. Please view our Grants Calendar for upcoming grant opportunities.

This grant is no longer offered.

Phase I and II Clinical Research Program Infrastructure Award

Background

Principal Investigator Name:

Brenda Weigel, MD & Emily Greengard MD

Project Title:

Phase I and II Clinical Research Program Infrastructure Award

Year Awarded:

2015

Cancer Research Category:

Category of Grant:

Phase I/II Infrastructure Grants

Medical, Nurse Researcher, Quality of LIfe:

Medical

Institution:

University of Minnesota

Expanding Innovative Pediatric Cancer Clinical Trial Access at Stanford

Background: The Stanford University School of Medicine, in partnership with the Lucile Packard Children's Hospital, has a reputation as one of the premier pediatric cancer research centers in the U.S. To date, our efforts have primarily focused on conducting research and participating in cooperative group and consortium clinical trials. With the recent recruitment of Drs.

Principal Investigator Name:

Maria-Grazia Roncarolo, M.D. & Sherri Spunt, M.D.

Project Title:

Expanding Innovative Pediatric Cancer Clinical Trial Access at Stanford

Year Awarded:

2015

Cancer Research Category:

General Pediatric Cancer

Category of Grant:

Phase I/II Infrastructure Grants

Medical, Nurse Researcher, Quality of LIfe:

Medical

Institution:

Stanford University

Children’s Hospital of Wisconsin- Milwaukee

Background: There is an urgent need for improved and safer therapies for the treatment of children, adolescents and young adults (AYA) diagnosed with high-risk, pediatric cancers. Testing of new therapies for pediatric cancers requires an experienced network of clinical scientists, research nurses, investigational pharmacists, regulatory experts and data coordinators in order to manage early-phase clinical trials.

Principal Investigator Name:

Michael J. Burke, MD

Project Title:

Building Capacity for the Clinical Trials Office at Children's Hospital of Wisconsin - Strengthening Phase I & II Trials Infrastructure

Year Awarded:

2015

Cancer Research Category:

General Pediatric Cancer

Category of Grant:

Phase I/II Infrastructure Grants

Medical, Nurse Researcher, Quality of LIfe:

Medical

Institution:

Children’s Hospital of Wisconsin - Milwaukee

Vanderbilt University Medical Center

The Vanderbilt Childhood Cancer program is a part of both the Monroe Carell Jr. Children's Hospital at Vanderbilt and the Vanderbilt-Ingram Cancer Center, an NCI-designated Comprehensive Cancer Center each of which were recognized for their excellence in the most recent U.S. News & World Report rankings [1, 2].

Principal Investigator Name:

James Whitlock, M.D.

Project Title:

Pediatric Oncology Translational Research Program

Year Awarded:

2009

Cancer Research Category:

Brain Tumors

Category of Grant:

Phase I/II Infrastructure Grants

Medical, Nurse Researcher, Quality of LIfe:

Medical

Institution:

Vanderbilt University Medical Center

Seattle Children's HOSPITAL

The outcome for some of the most common childhood cancers remains unacceptable and for those who survive, long-term medical complications of therapy are a reality.

Principal Investigator Name:

Julie Park, MD

Project Title:

Accelerating Access to Cellular Therapies for the Treatment of Childhood Malignancies

Year Awarded:

2013

Cancer Research Category:

Category of Grant:

Phase I/II Infrastructure Grants

Medical, Nurse Researcher, Quality of LIfe:

Medical

Institution:

Seattle Children’s Hospital and Regional Medical Center

Children's Hospital of Pittsburgh

Children's Hospital of Pittsburgh (CHP) has a long tradition of participation in pediatric oncology research. CHP is one of 21 institutions in the Children's Oncology Group (COG) Phase 1 Consortium and 1 of 10 in the Pediatric Brain Tumor Consortium (PBTC). We enrolled the largest number of patients to PBTC trials and are the third highest enroller to COG Phase I studies this year.

Principal Investigator Name:

Jean Tersak, MD

Project Title:

Children's Hospital of Pittsburgh of UPMC Phase 1-2 Infrastructure Support Grant

Year Awarded:

2013

Cancer Research Category:

Category of Grant:

Phase I/II Infrastructure Grants

Medical, Nurse Researcher, Quality of LIfe:

Medical

Institution:

University of Pittsburgh

Children's Hospital Colorado

Most children diagnosed with cancer today will be cured. Unfortunately for some with very difficult-to-treat cancers, standard therapy is ineffective. The Experimental Therapeutics Program (ETP) within the Center for Cancer and Blood Disorders at Children's Hospital Colorado was created to support the development of and enhance the access to the most promising new therapies for children, adolescents and young adults.

Principal Investigator Name:

Lia Gore, MD

Project Title:

Children's Hospital Colorado Experimental Therapeutics Program

Year Awarded:

2013

Cancer Research Category:

General Pediatric Cancer

Category of Grant:

Phase I/II Infrastructure Grants

Medical, Nurse Researcher, Quality of LIfe:

Medical

Institution:

Children’s Hospital Colorado

Columbia University

Survival following chemotherapy for pediatric malignancy remains one of the most stunning successes of modern medicine. Nevertheless, there remains a subset of patients with aggressive disease for whom novel therapies are required.

Principal Investigator Name:

Julia Glade Bender, MD

Project Title:

Columbia University Developmental Therapeutics Program: Striving for Excellence

Year Awarded:

2013

Cancer Research Category:

General Pediatric Cancer

Category of Grant:

Phase I/II Infrastructure Grants

Medical, Nurse Researcher, Quality of LIfe:

Medical

Institution:

Columbia University

Case Western Reserve University

Innovative pediatric developmental therapeutic programs are critical to the identification of novel agents that offer the prospect of more effective and less toxic therapies for pediatric cancers.

Principal Investigator Name:

Letterio, John MD & Matloub, Yousif MD

Project Title:

The Phase I/II Trials Collaborative for Children, Adolescents, and Young Adults at UH Rainbow Babies & Children's Hospital and the Case Comprehensive Cancer Center

Year Awarded:

2013

Cancer Research Category:

Category of Grant:

Phase I/II Infrastructure Grants

Medical, Nurse Researcher, Quality of LIfe:

Medical

Institution:

Case Western Reserve University

Research Institute at Nationwide Children's Hospital

The ALSF Infrastructure funding will help support the second phase of the Clinical Research Office growth at Nationwide Children's Hospital. Led by Sarah O'Brien, MD And Timothy Cripe, MD, PhD, the second phase of growth includes the successful launching of investigator-initiated and early phase protocol to the kids being treated at Nationwide.

Principal Investigator Name:

Sarah O'Brien, MD and Timothy Cripe, MD, PhD

Project Title:

Nationwide Children's Hospital Phase I/II Infrastructure

Year Awarded:

2013

Cancer Research Category:

Ewing Sarcoma

Category of Grant:

Phase I/II Infrastructure Grants

Medical, Nurse Researcher, Quality of LIfe:

Medical

Institution:

Research Institute at Nationwide Children's Hospital

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