ALSF Childhood Cancer Research Grants
With your support, we have been able to fund outstanding research, leading toward cures and improved quality of life for children with cancer. Browse through more than 1,500 funded projects below.
Use the search tool to refine your results. You can also click on a heading to sort by project title, institution name, or year the grant was awarded. Click on the project title to read more information.
You can learn about ALSF's grant review process here.
ALSF Funded Research Projects
| Project Title | Institution / Principal Investigator(s) | Grant Type | Year | State |
|---|---|---|---|---|
| Enhancing Communication about Sexual and Reproductive Health between Oncology Clinicians and Adolescent and Young Adults | Connecticut Children’s Medical Center / Dr. Natasha Frederick, PhD | Psychosocial Launch Grant | 2018 | Connecticut |
| Surviving Cancer CAMPetently: Evidence-based Care Delivered at Family Camp | Nemours A.I. duPont Hospital for Children / Melissa Alderfer, PhD | Psychosocial Family Impact Grant | 2018 | Delaware |
| Impact of Pediatric Germline Testing in a Pediatric Cancer Predisposition Clinic | Children’s Hospital of Philadelphia / Lisa Schwartz, PhD | Psychosocial Family Impact Grant | 2018 | Pennsylvania |
| The Role of Pyruvate Dehydrogenase in Leukemia | University of Texas Southwestern Medical Center at Dallas / Michalis Agathocleous, PhD | 'A' Award Grants | 2018 | Texas |
| Mechanisms of PAX3-FOXO1 and HES3 Cooperation in Rhabdomyosarcoma | Nationwide Children’s Hospital / Genevieve Kendall, PhD | 'A' Award Grants | 2018 | Ohio |
| Functional Characterization of RELA Fusion Ependymoma as a Basis for Therapeutic Targeting | St. Jude Children’s Research Hospital / Stephen Mack, PhD | 'A' Award Grants | 2018 | Tennessee |
| Physical Properties of Drug-Resistant Leukemia Cells | Children’s Hospital Los Angeles / Yong-mi Kim, MD/PhD | Innovation Grants | 2018 | California |
| Targeting the ALT Pathway to Induce Synthetic Lethality and Treat Poor Outcome Pediatric Tumors | University of California, Davis / Wolf-Dietrich Heyer, PhD | Innovation Grants | 2018 | California |
| Alternative Splicing Driven by MYCN Activates RAS-MAPK in Neuroblastoma | University of California San Francisco / William Weiss, MD/PhD | Innovation Grants | 2018 | California |
| RNA-ECS to Quantify Rare Clonal RNA Species at Diagnosis, Remission and Relapse from the COG AAML1031 Study | Washington University / Todd Druley, MD/PhD | Innovation Grants | 2018 | Missouri |
| Targeting Glutamine Addiction in Diffuse Intrinsic Pontine Gliomas (DIPGs) | University of Michigan / Sriram Venneti, MD/PhD | Innovation Grants | 2018 | Michigan |
| RNA Methylation in Metabolically Disrupted Pediatric Cancers | University of Texas Health Science Center at San Antonio / Patricia Dahia, MD/PhD | Innovation Grants | 2018 | Texas |
| Is SIRT5 a Therapy Target in Acute Lymphoblastic Leukemia? | University of Utah / Michael Deininger, MD/PhD | Innovation Grants | 2018 | Utah |
| Targeting Oncogenic RAS in Pediatric Leukemia | Dana-Farber Cancer Institute / Loren Walensky, MD/PhD | Innovation Grants | 2018 | Massachusetts |
| Identifying New Therapeutic Targets in Fibrolamellar Hepatocellular Carcinoma | Stanford University / Julien Sage, PhD | Innovation Grants | 2018 | California |
| Modeling and Therapeutic Targeting of p21-Activated Kinase Members in High-Risk Rhabdomyosarcoma | Baylor College of Medicine / Jason Yustein, MD/PhD | Innovation Grants | 2018 | Texas |
| Molecular Landscape for Targeted Therapy in Retinoblastoma | University of Miami / James Harbour, MD | Innovation Grants | 2018 | Florida |
| Targeting KDM6B in Pediatric Leukemia | Washington University / Grant A. Challen, PhD | Innovation Grants | 2018 | Missouri |
| Energy Balance Strategies for Decreasing Chemotherapy-Induced Cardiotoxicity | University of Texas M.D. Anderson Cancer Center / Eugenie Kleinerman, MD | Innovation Grants | 2018 | Texas |
| Circulating Repetitive Element RNAs as an Osteosarcoma Marker | Children’s Hospital Los Angeles / David Cobrinik, MD/PhD | Innovation Grants | 2018 | California |
| Nuclear Receptor Tyrosine Kinases Mediating Chromatin Remodeling & Checkpoint Adaption | Children’s Cancer Therapy Development Institute / Charles Keller, MD | Innovation Grants | 2018 | Oregon |
| Olfactory Ensheathing Cells for Pediatric Glioma Gene/Cell Therapy | Massachusetts General Hospital / Bakhos Tannous, PhD | Innovation Grants | 2018 | Massachusetts |
| Immuno-therapeutic Targeting of CD56 in CBA2T3/GLIS2-AML in Children | Fred Hutchinson Cancer Research Center / Soheil Meshinchi, MD/PhD | Reach Grants | 2018 | Washington |
| Identifying a Therapeutic Partner for TAK228 for Pediatric Phase II Brain Tumor Studies | The Johns Hopkins University School of Medicine / Eric H. Raabe, MD/PhD | Reach Grants | 2018 | Maryland |
| Epigenetic Targeted Therapy and Resistance in Pediatric Rhabdoid Tumor | Ann & Robert H. Lurie Children’s Hospital of Chicago / Rintaro Hashizume, MD/PhD | Reach Grants | 2018 | Illinois |
| Therapeutic Targeting of Childhood Leukemia by Pharmacological Inhibition of Proteolytic Cleavage of MLL1 | Northwestern University (Illinois) / Zibo Zhao, PhD | Young Investigator Grants | 2018 | Illinois |
| NUDT15 Polymorphisms and Individualization of Thiopurine Therapy in Children with Acute Lymphoblastic Leukemia | St. Jude Children’s Research Hospital / Takaya Moriyama, MD/PhD | Young Investigator Grants | 2018 | Tennessee |
| Modeling GATA2 Associated MDS/AML Predisposition Syndrome Using Color-Barcoding and Mutagenesis in Zebrafish | Dana-Farber Cancer Institute / Serine Avagyan, PhD | Young Investigator Grants | 2018 | Massachusetts |
| Investigating the role of BAI1 in the Metastasis of Medulloblastoma | University of Alabama at Birmingham / Satoru Osuka, MD/PhD | Young Investigator Grants | 2018 | Alabama |
| Effect of SLCO Polymorphisms on High-Dose Methotrexate Clearance in Pediatric Oncology Patients | Vanderbilt University Medical Center / Rachael Schulte, MD | Young Investigator Grants | 2018 | Tennessee |
| Targeting the Metabolic Drivers of Chemo Resistance in Acute Myeloid Leukemia | Harvard University / Nick van Gastel, PhD | Young Investigator Grants | 2018 | Massachusetts |
| Augmenting Chimeric Antigen Receptor T Cell Induced Epitope Spreading for Pediatric Solid Tumors | Children’s Hospital of Philadelphia / Michael Leibowitz, MD/PhD | Young Investigator Grants | 2018 | Pennsylvania |
| Divergent Core Transcriptional Regulatory Circuitries to Highlight Context-Specific Vulnerabilities in AML | Dana-Farber Cancer Institute / Maxim Pimkin, MD/PhD | Young Investigator Grants | 2018 | Massachusetts |
| MYC-driven Core Regulatory Circuits in Neuroblastoma | Dana-Farber Cancer Institute / Mark Zimmerman, PhD | Young Investigator Grants | 2018 | Massachusetts |
| Describing the Biological Impacts of Gain-of-function SAMD9 Mutations | Vanderbilt University Medical Center / Jason Schwartz, MD/PhD | Young Investigator Grants | 2018 | Tennessee |
| Novel Antibodies to the C2-set Domain of CD33 for Acute Myeloid Leukemia Immunotherapy | Fred Hutchinson Cancer Research Center / Colin Godwin, MD | Young Investigator Grants | 2018 | Washington |
| Accessing Combinatorial Effect of PARP Inhibitor with DNA Damaging Agent in Rhabdomyosarcoma at Single Cell Resolution | Massachusetts General Hospital / Chuan Yan, PhD | Young Investigator Grants | 2018 | Massachusetts |
| Cooperating Signaling Networks Regulate Cell Survival of Pediatric Ph-like ALL | University of Pennsylvania / Christian Hurtz, PhD | Young Investigator Grants | 2018 | Pennsylvania |
| Beyond Febrile Neutropenia: Risks Associated with Antibiotic Choice in Children with Leukemia that Undergo Transplant | Children’s Hospital of Philadelphia / Caitlin Elgarten, MD | Young Investigator Grants | 2018 | Pennsylvania |
| Pedi-PRESTO: Pediatric Patient-Reported Symptom Tracking in Oncology | Children’s Hospital of Philadelphia / Allison Barz Leahy, MD | Young Investigator Grants | 2018 | Pennsylvania |
| Interrogation of Neuroblastoma Dependencies and RNAs on the Core-Regulatory Circuitry for Therapeutic Inhibition | St. Jude Children’s Research Hospital / Adam Durbin, PhD | Young Investigator Grants | 2018 | Tennessee |
| Endocrine Disrupting Pesticides, Neonatal Hormones and Risk of Testicular Germ Cell Tumors | University of California Berkeley / Catherine Metayer, MD, PhD | Epidemiology Grants | 2018 | California |
| Neighborhood Factors, Acute Kidney Injury and Disparities in Pediatric Acute Myeloid Leukemia | Children’s Hospital of Philadelphia / Richard Aplenc, MD/PhD | Epidemiology Grants | 2018 | Pennsylvania |