ALSF Childhood Cancer Research Grants
With your support, we have been able to fund outstanding research, leading toward cures and improved quality of life for children with cancer. Browse through more than 1,500 funded projects below.
Use the search tool to refine your results. You can also click on a heading to sort by project title, institution name, or year the grant was awarded. Click on the project title to read more information.
You can learn about ALSF's grant review process here.
ALSF Funded Research Projects
Project Title | Institution / Principal Investigator(s) | Grant Type | Year |
State![]() |
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Targeting the Surface-ome of Embryonal Brain Tumors | Institut Curie / Olivier Ayrault, PhD | Crazy 8 Pilots | 2019 | |
Tracking Ewing Sarcoma Origin by Developmental and Trans-species Genomics | St. Anna Children’s Cancer Research Institute / Heinrich Kovar, PhD | Crazy 8 Awards | 2020 | |
The Role of Affective and Cognitive-Executive Processes and Structural Brain Abnormalities on Social Adjustment in Pediatric Brain Tumor Survivors | University of Calgary / Fiona Schulte, PhD | Psychosocial Grants | 2016 | Alberta |
Novel Therapy of Heterogeneous B-cell Acute Lymphocytic Leukemia by Targeting Convergent Oncogenic Mediators STATs | University of Alberta / Hasan Uludag, PhD | Innovation Grants | 2019 | Alberta |
Sexuality in Adolescents with Cancer | University of Calgary / Nancy Moules, PhD | Nurse Researcher Grants | 2013 | Alberta |
Investigating the role of BAI1 in the Metastasis of Medulloblastoma | University of Alabama at Birmingham / Satoru Osuka, MD/PhD | Young Investigator Grants | 2018 | Alabama |
A Nurse-Led Structured Discharge Teaching Intervention for Parents of Newly Diagnosed Pediatric Oncology Patients | University of Alabama at Birmingham / Wendy Landier, RN/PhD | Nurse Researcher Grants | 2016 | Alabama |
End-of-Life Care of Children with Cancer: Variation and Stakeholder Priorities | University of Alabama at Birmingham / Emily Johnston, MD | Young Investigator Grants | 2017 | Alabama |
Inducing Neuroblastoma Differentiation In Vivo | University of Alabama at Birmingham / Ankur Saxena, PhD | Innovation Grants | 2023 | Alabama |
Effects of CNS Treatment on Antioxidant Level, Apoptosis and Cognitive Abilities in Childhood Leukemia | University of Arizona / Ki Moore, R.N./Ph.D. | Nurse Researcher Grants | 2012 | Arizona |
COPE in Parents of Children Diagnosed with Cancer | University of Arizona / Gloanna Peek | Nurse Researcher Grants | 2011 | Arizona |
Effects of CNS Treatment on the Hippocampus | University of Arizona / Ki Moore | Nurse Researcher Grants | 2009 | Arizona |
Reciprocal interactions between tumor killer dendritic cells and tumor-induced regulatory T lymphocytes | University of Arizona / Nicolas Larmonier, PhD | Young Investigator Grants | 2008 | Arizona |
Identifying Epistatic Suppressors of Oncohistone in Pediatric High-Grade Gliomas | BC Cancer (Provincial Health Services Authority) / Carol Chen, PhD | Young Investigator Grants | 2020 | British Columbia |
Predicting Outcome for Patients with Metastatic Neuroblastoma by Analysis of Bone Marrow and Blood for a Neuroblastoma Gene Expression Signature | Children’s Hospital Los Angeles / Robert Seeger | Innovation Grants | 2010 | California |
Characterization of Pre-Leukemia Associated with Familial RUNX1 Mutations | Stanford University / Ravi Majeti, MD/PhD | RARE Grant Program (Research Accelerating RUNX1 Exploration) | 2016 | California |
A Pilot Study of the Feasibility and Acceptability of an Interactive Computerized Symptom Assessment Tool to Assess Disease and Treatment-Related Symptoms Experienced by Children with Cancer | University of California San Francisco / Tina Baggott, RN, PhD, PNP | Nurse Researcher Grants | 2009 | California |
Identification of Aberrantly Methylated Differentially Expressed Genes to Distinguish High- vs. Low-Risk Retinoblastoma | Children’s Hospital Los Angeles / Jesse Berry, MD | Reach Grants | 2023 | California |
Preclinical Development of a First-in-Class PCNA Inhibitor for Treating Neuroblastoma | City of Hope National Medical Center / Linda Malkas, PhD | Reach Grants | 2019 | California |
Phase II Trial of Poly-ICLC in Pediatric Low Grade Gliomas | University of California, San Diego / Donald Durden, MD, PhD | Springboard Grants | 2013 | California |
Child's Exposure to Radiation from Medical Imaging and the Risk of Childhood Leukemia: Pooled Analyses from the Childhood Leukemia International Consortium (CLIC) | University of California Berkeley / Catherine Metayer, MD/PhD & Steve Selvin, PhD | Epidemiology Grants | 2016 | California |
Intervention Development and Evaluation to Reduce Disparities in Quality of Life for Latino Families Impacted by Cancer | The Regents of the University of California, Irvine / Michelle Fortier, PhD | Psychosocial Family Impact Grant | 2019 | California |
Targeting the Accomplices of MYC in MYC-driven Medulloblastoma | Sanford-Burnham Medical Research Institute / Robert Wechsler-Reya, Ph.D. | Innovation Grants | 2014 | California |
131 I-MIBG Imaging and Therapy for Neuroblastoma: Infrastructure Proposal | University of California San Francisco / Katherine Matthay, MD | Phase I/II Infrastructure Grants | 2010 | California |
Blockade of p53 and Aurora A in Therapy Resistant Neuroblastoma | University of California San Francisco / William Clay Gustafson, MD, PhD | 'A' Award Grants | 2011 | California |
Single-cell Profiling of Pediatric Bone Sarcomas | University of California, Los Angeles / Alice Soragni, PhD | Single-cell Pediatric Cancer Atlas Grant | 2019 | California |
Investigation of Genetic and Molecular Mechanisms of Second Malignant Neoplasms in a Mouse Model | University of California San Francisco / Jean Nakamura | Young Investigator Grants | 2011 | California |
Next-Generation Therapies for Hedgehog Pathway-Dependent Tumors | Lucile Packard Children’s Hospital at Stanford University School of Medicine / James Chen, PhD | Innovation Grants | 2013 | California |
The influence of the raphe nucleus and serotonin on progression of diffuse intrinsic pontine glioma | Stanford University / Richard Drexler, MD/PhD | Young Investigator Grants | 2024 | California |
Identification and Characterization of an Epigenetic Program that Maintains the Self-Renewal of MLL Myeloid Leukemia Stem Cells | Stanford University / Hon-Kit Wong | Young Investigator Grants | 2010 | California |
High-Throughput Gene-Editing via Microfluidic Cell Deformability to Enable Off-the-Shelf Allogeneic Cellular Immunotherapies | University of California, Los Angeles / Steven Jonas, MD/PhD | Young Investigator Grants | 2017 | California |
Understanding and inhibiting mechanisms of metastatic spread in osteosarcoma | University of California San Francisco / Alejandro Sweet-Cordero, MD | Crazy 8 Awards | 2022 | California |
Alternative Splicing Driven by MYCN Activates RAS-MAPK in Neuroblastoma | University of California San Francisco / William Weiss, MD/PhD | Innovation Grants | 2018 | California |
Targeted Inhibition of Signaling Networks in Pediatric Glioblastoma Stem Cells | University of California Berkeley / Erin Simonds, PhD | Young Investigator Grants | 2013 | California |
Studying the clonal dynamics and evolution of leukemia using molecular barcodes | Lucile Packard Children’s Hospital at Stanford University School of Medicine / Matthew Porteus, MD, PhD | Innovation Grants | 2011 | California |
Identifying New Therapeutic Targets in Fibrolamellar Hepatocellular Carcinoma | Stanford University / Julien Sage, PhD | Innovation Grants | 2018 | California |
Synergistic Activity of Anti-GD2 Antibody and CD47-Blockade for Immunotherapy of Neuroblastoma and Osteosarcoma | The Board of Trustees of the Leland Stanford Junior University / Robbie Majzner, MD | 'A' Award Grants | 2019 | California |
Modeling osteosarcoma to identify novel therapeutic targets. | Stanford University / Julien Sage | Young Investigator Grants | 2006 | California |
Blockade of MYCN in neuroblastoma | University of California San Francisco / William Weiss, MD/PhD | Innovation Grants | 2011 | California |
Antibody Targeted Natural Killer Cell-Derived Extracellular Vesicles for the Treatment of Childhood Acute Lymphoblastic Leukemia and Neuroblastoma | Children’s Hospital Los Angeles / Robert Seeger, MD & Alan Wayne, MD | Innovation Grants | 2015 | California |
Single Cell Signaling Profiles In High-Risk Pediatric Leukemia | Stanford University / Kara Davis | Young Investigator Grants | 2010 | California |
Targeting TGFb Pathway Dependencies in Group 3 Medulloblastoma | University of California San Francisco / Zulekha Qadeer, PhD | Young Investigator Grants | 2019 | California |
Single Cell Analysis of Leukemia Initiation | Stanford University / Michael Cleary, MD | Innovation Grants | 2015 | California |
Investigating Racial Disparities in Pediatric Acute Leukemia | University of California San Francisco / Lena Winestone, MD | Young Investigator Grants | 2016 | California |
Role of Fetal Growth in Pediatric Rhabdomyosarcoma | University of California Berkeley / Catherine Metayer, MD, PhD | Epidemiology Grants | 2013 | California |
Enhancing Effectiveness of Immune Checkpoint Therapy in Neuroblastoma | Children’s Hospital Los Angeles / Shahab Asgharzadeh, MD | Innovation Grants | 2015 | California |
Identifying novel biomarkers for risk stratification in t-cell acute lymphoblastic leukemia (ALL). | University of California San Francisco / Michelle Hermiston, MD, PhD | Young Investigator Grants | 2009 | California |
Targeted Degradation of Proliferative Transcription Factors in Pediatric Cancers | University of California at Santa Cruz / Seth Rubin, PhD | Innovation Grants | 2017 | California |
Development of a comprehensive liquid biopsy-based genomics platform for pediatric solid tumors | Children’s Hospital Los Angeles / Jaclyn Biegel | Catalyst Grants | 2023 | California |
Central Venous Catheter (CVC) - Related Bloodstream Infections in Pediatric Cancer | Children’s Hospital Los Angeles / Rita Secola | Nurse Researcher Grants | 2009 | California |
Optimizing EGFR targeted therapy in pediatric malignant glioma. | University of California San Francisco / Theodore Nicolaides | Young Investigator Grants | 2009 | California |
MLL Oncogene-Dependent Enhancer Reprogramming Promotes Leukemogenesis | Stanford University / Feng Pan, PhD | Young Investigator Grants | 2019 | California |
Targeting Secondary Mutations in Juvenile Myelomonocytic Leukemia | University of California San Francisco / Elliot Stieglitz, MD | Young Investigator Grants | 2015 | California |
The role of OCT4 in self-renewal signaling and drug-resistance of childhood acute lymphoblastic leukemia | Children’s Hospital Los Angeles / Markus Muschen | Innovation Grants | 2008 | California |
Develop a Therapeutic Vaccine Approach by Removing Viral Immune Evasion | University of California, Los Angeles / Ren Sun, PhD | Springboard Grants | 2013 | California |
Defining how thymic expression of oncofetal antigens hinders the efficacy of pediatric-cancer focused immunotherapies | Stanford University / Adrienne Long, MD/PhD | Young Investigator Grants | 2024 | California |
Optimizing TCRαβ+/CD19+-depleted haploidentical HSCT for ALL using donor-derived genome-edited CAR T cells | Stanford University School of Medicine / Alice Bertaina, MD/PhD | Reach Grants | 2019 | California |
A Novel Target for Neuroblastoma Treatment | Beckman Research Institute of City of Hope / Linda Malkas, Ph.D. | Reach Grants | 2014 | California |
Oncogenic Hedgehog Pathway Activation by a Putative Rho GTPase-Activating Protein | Lucile Packard Children’s Hospital at Stanford University School of Medicine / Jun Ni, PhD | Young Investigator Grants | 2013 | California |
Investigation of Oncogenic Long Non-coding RNAs in Ewing sarcoma | Lucile Packard Children’s Hospital at Stanford University School of Medicine / Siu Ping Ngok, PhD | Young Investigator Grants | 2014 | California |
The Identification of Neuroblastoma Cancer Stem Cells. | Stanford University / Robert Cho | Young Investigator Grants | 2007 | California |
Targeting eEF2 Kinase in Neuroblastoma | University of California San Francisco / William Weiss, M.D., Ph.D. | Innovation Grants | 2014 | California |
Space-Time Analysis of the California Birth Cohort: 30 Years of Childhood Cancer | University of California Berkeley / Steve Selvin, PhD | Epidemiology Grants | 2015 | California |
Genetic Dissection of Cancer Drug Resistance and Toxicity Using Haploid Human Cells | Stanford University / Ramin Dubey, PhD | Young Investigator Grants | 2015 | California |
Altered Cerebral Blood Flow after Pediatric Posterior Fossa Brain Tumor Treatment | Children’s Hospital Los Angeles / Mary Baron Nelson, RN/PhD | Nurse Researcher Grants | 2016 | California |
Histone H3.3 Targeted Therapy for Pediatric High-grade Gliomas | University of California, Davis Medical Center / Paul Knoepfler, PhD | Innovation Grants | 2015 | California |
Improving Thymus Function by RB Inactivation | Lucile Packard Children’s Hospital at Stanford University School of Medicine / Julien Sage, PhD | Springboard Grants | 2012 | California |
Novel Resilience Genes Required for Cerebellum Development and Medulloblastoma Survival | University of California San Francisco / Stephen Fancy, PhD, DVM | Innovation Grants | 2023 | California |
Immunotherapeutic Targeting of Stem Cells in Pediatric Brain Tumors | Harbor - UCLA Medical Center / Joseph Lasky | Young Investigator Grants | 2008 | California |
Physical Properties of Drug-Resistant Leukemia Cells | Children’s Hospital Los Angeles / Yong-mi Kim, MD/PhD | Innovation Grants | 2018 | California |
A comprehensive public resource for fusion-negative sarcoma sequencing data | University of California San Francisco / Alejandro Sweet-Cordero, MD & Richard Gorlick, MD | Crazy 8 Pilots | 2019 | California |
Endocrine Disrupting Pesticides, Neonatal Hormones and Risk of Testicular Germ Cell Tumors | University of California Berkeley / Catherine Metayer, MD, PhD | Epidemiology Grants | 2018 | California |
Integrative Genomic and Immunogenomic Analysis of Neuroblastoma | University of California at Santa Cruz / David Haussler, PhD | Innovation Grants | 2015 | California |
Identifying Ewing Sarcoma Developmental Vulnerabilities | Children’s Hospital Los Angeles / Elena Vasileva, PhD | Young Investigator Grants | 2023 | California |
Determinants of Testicular Germ Cell Tumor Platinum Sensitivity and Resistance | University of California, San Diego / Paolo Abada | Young Investigator Grants | 2012 | California |
Multiplex Ion Beam Imaging of Pediatric Cancers | Stanford University School of Medicine / Crystal L. Mackall, MD | Crazy 8 Pilots | 2019 | California |
Identifying Drug Resistant Mutations in Ph-like Acute Lymphoblastic Leukemia | University of California San Francisco / Mignon Loh, M.D. | Innovation Grants | 2014 | California |
A Combinatorial Approach to Target the Tumor-Initiating and Transit Amplifying Cellular Subpopulations in Diffuse Intrinsic Pontine Glioma (DIPG) | Stanford University / Michelle Monje, MD, PhD | 'A' Award Grants | 2011 | California |
Harmonizing Data Sharing Efforts towards a Federated Data Model | University of California at Santa Cruz / Olena M. Vaske, PhD & David Haussler, PhD | Crazy 8 Pilots | 2019 | California |
Targeting Oncogenic N-MYC Complexes in High-Risk Neuroblastoma | The Regents of the University of California San Francisco / Bo Qiu, MD/PhD | Young Investigator Grants | 2023 | California |
Characterization of the Role of Chromosome 1p Deletion in MYCN-Amplified Neuroblastoma | University of California San Francisco / Miller Huang, PhD | Young Investigator Grants | 2013 | California |
Targeting inhibitory phosphatase signaling in high-risk childhood ALL | University of California San Francisco / Markus Muschen, MD, PhD | Innovation Grants | 2011 | California |
Understanding the Role of Translational Control in Humanized Mouse Models for Medulloblastoma | University of California San Francisco / Ozlem Aksoy, PhD | Young Investigator Grants | 2015 | California |
Neural Stem Cell-Mediated Drug Delivery for Targeted Treatment of Medulloblastoma | Beckman Research Institute of City of Hope / Margarita Gutova, MD | Reach Grants | 2013 | California |
131-I-MIBG and Targeted Therapy for Neuroblastoma: Infrastructure Proposal. | University of California San Francisco / Katherine Matthay, MD | Phase I/II Infrastructure Grants | 2007 | California |
Factors Affecting Parental Satisfaction, Anxiety and Comprehension of the Informed Consent in Pediatric Oncology Clinical Trials | University of California, San Diego / Paula Aristizabal, MD | Psychosocial Grants | 2015 | California |
Developing and Distributing a Pediatric Spinal Cord High-grade Glioma Model | Stanford University / Michelle Monje, MD/PhD | Innovation Grants | 2016 | California |
Pain and Symptom Experiences in Children with Cancer | University of California, Los Angeles / Eufemia Jacob, PhD, RN | Nurse Researcher Grants | 2007 | California |
Targeting Childhood Brain Cancer in a Dish to Catalyze New Therapies | University of California, Davis Medical Center / Paul Knoepfler, PhD | Innovation Grants | 2017 | California |
Enhancing TKI Therapy in Ph-Like Leukemia | The Regents of the University of California, Irvine / David Fruman, PhD | Reach Grants | 2022 | California |
Preclinical Studies of Gli1 Inhibition in Ewing Family Tumors | Children’s Hospital Los Angeles / William May | Innovation Grants | 2008 | California |
Targeting Aberrant Hh Signaling with BET Bromodomain Inhibition as a Novel Therapeutic Strategy Against MB and DIPG | Lucile Packard Children’s Hospital at Stanford University School of Medicine / Yujie Tang, PhD | Young Investigator Grants | 2014 | California |
An Intersection of Cell Metabolism and Differentiation in Childhood Sarcomas | Cedars-Sinai Medical Center / Sandra Orsulic, PhD | Innovation Grants | 2013 | California |
The Role of Tumor Heterogeneity in Relapse of Pediatric Acute Myeloid Leukemia | Children’s Hospital & Research Center at Oakland / Cheryl Peretz, MD | Young Investigator Grants | 2019 | California |
Single-cell RNA-seq Profiling of Transcriptional Transition States During Human Retinoblastoma | Children’s Hospital Los Angeles / Sunhye Lee, PhD | Young Investigator Grants | 2016 | California |
Expanding Innovative Pediatric Cancer Clinical Trial Access at Stanford | Stanford University / Maria-Grazia Roncarolo, M.D. & Sherri Spunt, M.D. | Phase I/II Infrastructure Grants | 2015 | California |
Defining the Role of a Novel, Developmentally Restricted Hematopoietic Stem Cell in Pediatric Leukemias | University of California at Santa Cruz / Camilla Forsberg, PhD | Innovation Grants | 2013 | California |
In vivo transdermal generation of CD33 CAR T-cells towards acute myeloid leukemia | University of California, Los Angeles / Ruby Sims, PhD | Young Investigator Grants | 2024 | California |
Identifying Novel Therapeutic Combinations with 131I-MIBG to Treat Relapsed and Refractory Neuroblastoma | The Regents of the University of California San Francisco / William Clay Gustafson, M.D., Ph.D. | Reach Grants | 2014 | California |
Blockade of Mycn in neuroblastoma | University of California San Francisco / William Weiss | Innovation Grants | 2008 | California |
New Approaches to Neuroblastoma Therapy (NANT) Consortium | Children’s Hospital Los Angeles / Robert Seeger, MD | Phase I/II Infrastructure Grants | 2006 | California |
Saturating CRISPR gene body scans in MLL-rearranged leukemia | Beckman Research Institute of City of Hope / Chun-Wei Chen, PhD | Innovation Grants | 2019 | California |
Maternal Comorbidities, Pharmaceutical Use and Childhood Cancers: A Record Linkage Study in Taiwan | University of California, Los Angeles / Julia Heck, PhD | Epidemiology Grants | 2017 | California |
GD2-directed CAR T cell therapy for H3K27M+ spinal cord diffuse midline glioma | Board of Trustees of the Leland Stanford Junior University / Michelle Monje | Catalyst Grants | 2021 | California |
Saving Lives, Saving Neurons, the Head Start Consortium for Young Children with Malignant Central Nervous System Tumors | Children’s Hospital Los Angeles / Jonathan Finlay, MD | Phase I/II Infrastructure Grants | 2007 | California |
Adoptive Immunotherapy of Tr1 Cells to Improve Outcome of Allo-HSCT Treatment for Pediatric AML | Stanford University / Maria-Grazia Roncarolo, MD & Rosa Bachetta, MD | Reach Grants | 2015 | California |
Perinatal Hormonal Biomarkers and Risk of Testicular Germ Cell Tumors | University of California Berkeley / Catherine Metayer, MD, PhD | Epidemiology Grants | 2014 | California |
Modeling Anaplastic Medulloblastoma using Cerebellar Stem Cells | Sanford-Burnham Medical Research Institute / Robert Wechsler-Reya, PhD | Innovation Grants | 2011 | California |
High-dimensional Biochemical CyTOF Analysis of Pediatric T cell Leukemias | University of California San Francisco / Jeroen Roose, PhD | Innovation Grants | 2015 | California |
Enhancing Immunotherapy of Neuroblastoma | The Regents of the University of California, San Diego / Alice Yu, MD/PhD & Mitchell Diccianni, PhD | Innovation Grants | 2016 | California |
Overcoming Glucocorticoid Resistance in Lymphoid Cancers | University of California San Francisco / Anica Wandler, PhD | Young Investigator Grants | 2017 | California |
Pediatric Developmental Therapeutics Center of Excellence at UCSF | University of California San Francisco / Katherine Matthay, MD, Kieuhoa Vo, MD, - Scholars: Amit Sabnis, MD, Lena Winestone, MD/MSHP, Beth Winger, MD/PhD, Bo Qiu, MD/PhD | Center of Excellence Grants | 2012 | California |
Targeting the ALT Pathway to Induce Synthetic Lethality and Treat Poor Outcome Pediatric Tumors | University of California, Davis / Wolf-Dietrich Heyer, PhD | Innovation Grants | 2018 | California |
Genomic Alterations in Medulloblastoma | Children’s Hospital Los Angeles / Shahab Asgharzadeh, MD | Young Investigator Grants | 2008 | California |
Overcoming Obstacles to Drug Development in Pediatric Cancer | Stanford University School of Medicine / Crystal L. Mackall, MD | Crazy 8 Pilots | 2019 | California |
Single-Cell Profiling of Acute Myeloid Leukemia for High-Resolution Chemo-immunotherapy Target Discovery | Stanford University School of Medicine / Charles Gawad, MD/PhD | Single-cell Pediatric Cancer Atlas Grant | 2019 | California |
Reversing the Oncogenic Roles of Misdirected Chromatin Remodeling in Synovial Sarcoma | Lucile Packard Children’s Hospital at Stanford University School of Medicine / Cigall Kadoch, PhD | Young Investigator Grants | 2013 | California |
Assess the activity of ABT-737 as a single agent against neuroblastoma cell lines grown in cell culture | Children’s Hospital Los Angeles / Theresa Harned, MD | Young Investigator Grants | 2006 | California |
Chemical Genetics and CRISPRi/a Screen for Novel Therapeutic Targets in a Humanized Model for MYCN Associated High-Risk Pediatric Neuroblastoma | University of California San Francisco / Zhenyi An, PhD | Young Investigator Grants | 2015 | California |
Targeting PI3Kdelta in Childhood Acute Lymphoblastic Leukemia | Children’s Hospital Los Angeles / Yong-mi Kim, MD & Nora Heisterkamp, PhD | Reach Grants | 2015 | California |
Detection of Circulating Tumor DNA in Pediatric Sarcomas | The Regents of the University of California San Francisco / Alejandro Sweet-Cordero, MD & Maximillian Diehn, MD/PhD (Stanford University) | Innovation Grants | 2016 | California |
Predicting Outcome and Ameliorating Toxicities of the Immunotherapy of Neuroblastoma | University of California, San Diego / Alice Yu, MD, PhD | Innovation Grants | 2011 | California |
In-vivo characterization of MYCN-driven immunosuppression | University of California San Francisco / William Weiss, MD/PhD | Innovation Grants | 2021 | California |
Long-Term Morbidity in Survivors of Childhood Cancer with Down Syndrome | University of California San Francisco / Shannon Raber | Nurse Researcher Grants | 2010 | California |
Application of Epigenetic Markers for Early Detection of Childhood Leukemia. | University of California San Francisco / Sheng Zhong | Epidemiology Grants | 2008 | California |
CLL-1 CAR-T cells with or without trametinib for the treatment of JMML | The Regents of the University of California San Francisco / Elliot Stieglitz, MD | R Accelerated Award Grants | 2023 | California |
Symptom Burden, Health-Related Quality of Life and Health Care Utilization Among Children Undergoing Hematopoietic Stem Cell Transplantation: Impact of Parent Sleep, Fatigue and Psychological Distress | Children’s Hospital Los Angeles / Jessica Ward, PhD | Nurse Researcher Fellowship Grant | 2017 | California |
STING Pathway Activation: The Missing Link between Genomic Instability and Antitumor Immunity in Osteosarcoma | University of California San Francisco / Elizabeth Young, MD | Young Investigator Grants | 2021 | California |
A CRISPRi Genetic Screen in Ewing sarcoma Identifies a Novel Dependence on Homologous Recombination DNA Repair | University of California San Francisco / Asmin Tulpule, MD/PhD | Young Investigator Grants | 2016 | California |
Modeling Pediatric Leukemia in the Zebrafish to Enable Discovery of New Anti-Leukemic Compounds | University of California, San Diego / David Traver, MD | Innovation Grants | 2012 | California |
Neural Crest Gene Regulatory Networks Underlying Normal Meningeal Development and Onset of Meningioma | California Institute of Technology / Ayyappa Raja Desingu Rajan, PhD | Young Investigator Grants | 2021 | California |
New Approaches to Neuroblastoma Therapy | Children’s Hospital Los Angeles / Robert Seeger | Phase I/II Infrastructure Grants | 2008 | California |
Circulating Repetitive Element RNAs as an Osteosarcoma Marker | Children’s Hospital Los Angeles / David Cobrinik, MD/PhD | Innovation Grants | 2018 | California |
Activation of Anti-Leukemia Immunity by Targeting Protein Arginine Methyltransferase | City of Hope National Medical Center / Ling Li, PhD | R Accelerated Award Grants | 2023 | California |
Neuronal Damage, Neurocognitive Losses and Quality of Life Following High-Dose Chemotherapy in Children with Brain Tumors | Children’s Hospital Los Angeles / Mary Nelson | Nurse Researcher Grants | 2009 | California |
Investigating the Role of Genetic and Epigenetic Variation in Risk of Childhood Acute Lymphoblastic Leukemia in Down Syndrome | University of California San Francisco / Adam de Smith, Ph.D. | 'A' Award Grants | 2014 | California |
Modeling Pediatric Leukemia in Zebra Fish to Enable Discovery of New Anti- Leukemic Compounds | University of California, San Diego / David Traver, MD | Innovation Grants | 2010 | California |
Role of PHF6 Mutations in Germline RUNX1 Deficiency Associated Hematopoietic Disorders | The Regents of the University of California San Francisco / Serine Avagyan, MD/PhD | RUNX1 Early Career Investigator Grants | 2021 | California |
Preclinical Testing of Candidate Therapeutics in a Pediatric Spinal Cord High-grade Glioma Model | Stanford University / Michelle Monje, MD/PhD | Innovation Grants | 2016 | California |
Role of Protocadherin-9 in Enabling Leukemia Cell Colonization of the CNS | National Jewish Health / Jordan Jacobelli, PhD | Innovation Grants | 2017 | Colorado |
DNA methylation in medulloblastoma | University of Colorado Denver / Rajeev Vibhakar, MD, PhD, MPH | Young Investigator Grants | 2007 | Colorado |
A Novel Adjunctive LAT-Activating CART (ALA-CART) Cell Platform for the Treatment of Acute Leukemia | University of Colorado Denver_ Anschutz Medical Campus / Catherine Danis, PhD | Young Investigator Grants | 2023 | Colorado |
Targeting the Six1/Eya Transcriptional Complex to Inhibit Pediatric Sarcomas | University of Colorado Denver / Heide Ford, Ph.D. | Innovation Grants | 2014 | Colorado |
Advancing Program Development and Support for the Pediatric Experimental Therapeutics Program at The Children's Hospital, Denver | Children’s Hospital Colorado / Lia Gore, MD | Phase I/II Infrastructure Grants | 2007 | Colorado |
Improving homing and activity of CAR T cells in pediatric sarcomas | University of Colorado Denver / Joselyn Cruz Cruz, PhD | Young Investigator Grants | 2024 | Colorado |
Children's Hospital Colorado Experimental Therapeutics Program | Children’s Hospital Colorado / Lia Gore, MD | Phase I/II Infrastructure Grants | 2013 | Colorado |
Understanding the role of CDK8 in protein synthesis for treating MYC-driven medulloblastoma | University of Colorado Denver / Dong Wang, PhD | Young Investigator Grants | 2024 | Colorado |
Expanding Access to New Agents for Cancer Treatment. | Children’s Hospital Colorado / Lia Gore, MD | Phase I/II Infrastructure Grants | 2006 | Colorado |
Expanding access to new agents for children with refractory cancers: the experimental therapeutics program at Children's Hospital of Colorado. | Children’s Hospital Colorado / Lia Gore, MD | Phase I/II Infrastructure Grants | 2009 | Colorado |
CDK12 Links Radiation Response to PARPi Sensitivity in Pediatric Glioma | University of Colorado Denver_ Anschutz Medical Campus / Nathan Dahl, MD | Innovation Grants | 2023 | Colorado |
Single Cell RNA Sequencing of Pediatric High- and Low-Grade Gliomas | University of Colorado Denver / Adam Green, MD and Jean Mulcahy Levy, MD | Single-cell Pediatric Cancer Atlas Grant | 2019 | Colorado |
A Cell Morphology Landscape of Pediatric Cancer Cell Lines | University of Colorado Denver_ Anschutz Medical Campus / Gregory Way, PhD | 'A' Award Grants | 2023 | Colorado |
Targeting Eya2 to Inhibit c-Myc driven Medulloblastoma Tumor Progression | University of Colorado Denver / Melanie Vincent, PhD | Young Investigator Grants | 2016 | Colorado |
Autophagy and mTOR Inhibition in Pediatric Gliomas with BRAF Mutations | University of Colorado Denver / Jean Mulcahy Levy, MD | Young Investigator Grants | 2014 | Colorado |
Live-Cell Surface Proteomic Characterization of Atypical Teratoid Rhabdoid Tumors Using High Throughout Multi-Color Flow | University of Colorado Denver / Siddhartha S. Mitra, PhD | Crazy 8 Pilots | 2019 | Colorado |
MicroRNAs 100 and 125b in Ewing sarcoma | University of Colorado Denver / Paul Jedlicka | Young Investigator Grants | 2010 | Colorado |
Development of a Novel Mer Tyrosine Kinase Inhibitor for Treatment of ALL | University of Colorado Denver / Doug Graham, MD, PhD | Reach Grants | 2013 | Colorado |
Exploiting Epigenetic Dependencies of Notch1 for Clinical Benefit | University of Colorado Denver / Patricia Ernst, Ph.D. | Innovation Grants | 2014 | Colorado |
Novel Genomic Diagnostics for Intracranial Germ Cell Tumors | Connecticut Children’s Medical Center Foundation, Inc. / Ching Lau, MD/PhD | Reach Grants | 2021 | Connecticut |
Elucidating the Initiation Mechanism of the Fanconi Anemia Pathway of DNA Damage Repair | Yale School of Medicine / Yong Xiong | Innovation Grants | 2010 | Connecticut |
Development of Nanoparticle-Encapsulated Chemo/Radio-Sensitizers for Intrathecal Delivery | Yale School of Medicine / Ranjit S. Bindra, MD/PhD & Mark Saltzman, PhD | Innovation Grants | 2017 | Connecticut |
Small-molecule screening for novel pediatric glioma radiosensitizers. | Yale School of Medicine / Ranjit Bindra | Young Investigator Grants | 2012 | Connecticut |
Enhancing Communication about Sexual and Reproductive Health between Oncology Clinicians and Adolescent and Young Adults | Connecticut Children’s Medical Center / Dr. Natasha Frederick, PhD | Psychosocial Launch Grant | 2018 | Connecticut |
Elucidating the Role of Human FAN1 Nuclease in DNA Crosslink Repair | Yale School of Medicine / Timsi Rao, PhD | Young Investigator Grants | 2016 | Connecticut |
Identifying Therapeutic Targets for MiT Associated Pediatric Cancers | Yale School of Medicine / Sean Landrette | Young Investigator Grants | 2012 | Connecticut |
Treating Brain Tumor by Changing Cell Division Pattern | Yale School of Medicine / Weimin Zhong | Innovation Grants | 2010 | Connecticut |
Developing an accurate genetic model for rhabdomyosarcoma therapy | Children’s Research Institute / Dawn Chandler, PhD | Young Investigator Grants | 2007 | District of Columbia |
An Engineered Nanoimmunotherapy for Treating Neuroblastoma | George Washington University / Rohan Fernandes, PhD | 'A' Award Grants | 2016 | District of Columbia |
Neurocognitive Assessments within COG: An Intensive, Integrated Model for Successfully Evaluating Children with High-Risk ALL | Children’s Research Institute / Kristina Hardy, PhD | Psychosocial Grants | 2014 | District of Columbia |
Preliminary Content Validation Steps for the Pediatric Oncology Patient Self-Report CTCAE | Children’s National Medical Center / Pamela Hinds | Nurse Researcher Grants | 2011 | District of Columbia |
Functional Analysis and Therapeutic Targeting of STAG2 Mutations in Ewing sarcoma | Georgetown University / Todd Waldman, MD, PhD | Innovation Grants | 2015 | District of Columbia |
Genetically Modified, Cord Blood Derived Natural Killer Cell Therapy for High Grade Pediatric Brain Tumors | Children’s Research Institute / Conrad Russell Cruz, MD, PhD | 'A' Award Grants | 2015 | District of Columbia |
Immune Stimulatory Antigen Loaded Particles (ISAPS) for the Treatment of Solid Childhood Tumors | Children’s National Medical Center / Suzanne Miles | Young Investigator Grants | 2009 | District of Columbia |
Child and Adolescent Preferences for Involvement in their Cancer Treatment Decisions | Children’s Research Institute / Katherine Kelly, Ph.D. | Nurse Researcher Grants | 2012 | District of Columbia |
Targeted regulation of acetylation as novel therapy for Ewing sarcoma. | Georgetown University / Jeffrey Toretsky | Innovation Grants | 2009 | District of Columbia |
Epigenetic regulation of self-renewal pathways in hematopoietic and leukemic stem cells | George Washington University / Alexandros Tzatsos, MD/PhD | Young Investigator Grants | 2012 | District of Columbia |
Screen to Intervene: A Family-Centered Approach to Identifying and Communicating Family Psychosocial Risk and Developing Evidence Based Clinical Pathways in Hematopoietic Stem Cell Transplantation | Alfred I duPont Hospital for Children / Anne Kazak, PhD | Psychosocial Grants | 2015 | Delaware |
Discovery of Inhibitors of MLL Fusion Proteins as Targeted Therapies for Pediatric Acute Leukemia | Nemours Center for Childhood Cancer Research / Andrew Napper | Innovation Grants | 2010 | Delaware |
Inhibition of Cathepsins to Treat Neuroblastoma | Alfred I duPont Hospital for Children / Robert Mason | Innovation Grants | 2008 | Delaware |
Surviving Cancer CAMPetently: Evidence-based Care Delivered at Family Camp | Nemours A.I. duPont Hospital for Children / Melissa Alderfer, PhD | Psychosocial Family Impact Grant | 2018 | Delaware |
LRP1 and Angiogenesis in Pediatric Malignant Glioma | Mayo Clinic Jacksonville / Takahisa Kanekiyo, MD, PhD | Young Investigator Grants | 2013 | Florida |
Novel Role of Hematopoietic Stem Cells in Immunologic Rejection of Malignant Pediatric Brain Tumors | University of Florida / Catherine Flores, PhD | Young Investigator Grants | 2015 | Florida |
Treatment for human hepatoblastoma based on recombinant adeno-associated virus vectors | University of Florida / Chen Ling | Young Investigator Grants | 2012 | Florida |
Development of AAV Vectors for Efficient Targeting and Elimination of Osteosarcoma Tumor-Initiating Cells | University of Florida / Steven Ghivizzani, Ph.D. | Innovation Grants | 2014 | Florida |
The use of hematopoietic stem and progenitor cells to reverse treatment resistance to PD-1 blockade | University of Florida / Catherine Flores, PhD | Innovation Grants | 2019 | Florida |
Phase I trial of multilamellar mRNA lipid particles for recurrent pediatric high grade glioma | University of Florida / Elias Sayour, MD/PhD | R Accelerated Award Grants | 2022 | Florida |
Casein Kinase 1 alpha Agonists as Novel Medulloblastoma Inhibitors | University of Miami Miller School of Medicine / David Robbins, PhD | Innovation Grants | 2012 | Florida |
Expanding Hope: Innovative Therapy at Shands Children's Hospital | University of Florida / Amy Smith | Phase I/II Infrastructure Grants | 2010 | Florida |
Molecular Landscape for Targeted Therapy in Retinoblastoma | University of Miami / James Harbour, MD | Innovation Grants | 2018 | Florida |
Phase I Trial of Indoximod in Combination with Temozolomide-based Therapy for Children with Progressive Primary Brain Tumors | Georgia Health Sciences University Research Institute, Inc. / Theodore Johnson, M.D., Ph.D. | Bio-Therapeutic Impact Award | 2014 | Georgia |
CHOA Experimental Therapy Pediatric Oncology Research. | Aflac Cancer Center and Blood Disorders Service of Children’s Healthcare of Atlanta / Howard Katzenstein, MD | Phase I/II Infrastructure Grants | 2006 | Georgia |
Mechanisms of PPM1D in Medulloblastoma Tumorigenesis and Invasion | Emory University / Robert Craig Castellino, MD | Bridge Grants | 2012 | Georgia |
PI-3 kinase as a novel and attractive target in pediatric cancer and neuroblastoma | Emory University / Donald Durden | Innovation Grants | 2008 | Georgia |
Reversing Feedback Immunosuppression during Oncolytic Virotherapy of Pediatric High Grade Glioma | Augusta University Research Institute, Inc. / Bangxing Hong, PhD | Reach Grants | 2023 | Georgia |
Targeting mechanisms of Siglec15-mediated immune evasion in hematologic malignancies | Emory University / Christopher Porter, MD | Innovation Grants | 2019 | Georgia |
Expansion of the Innovative Therapies Program to Include the Development of a Pediatric Neuro-Oncology Translational Research Program | Aflac Cancer Center and Blood Disorders Service of Children’s Healthcare of Atlanta / Howard Katzenstein, MD | Phase I/II Infrastructure Grants | 2010 | Georgia |
WIP1 Modulates Responsiveness of MB to Genotoxic Stress. | Aflac Cancer Center and Blood Disorders Service of Children’s Healthcare of Atlanta / Robert Craig Castellino, MD | Young Investigator Grants | 2006 | Georgia |
The Role of LIN28B-let-7-PBK Axis on the Growth and Metastasis of Group 3 Medulloblastoma | Emory University / Shubin Shahab, MD/PhD | Young Investigator Grants | 2021 | Georgia |
IDO-based Immunotherapy for Pediatric Brain Tumors | Georgia Health Sciences University Research Institute, Inc. / Theodore Johnson, MD, PhD | 'A' Award Grants | 2013 | Georgia |
Feasibility Study of Dual Inhibition of MDM2 and Tubulin in Treatment of AML | Emory University / Muxiang Zhou, MD | Reach Grants | 2023 | Georgia |
The anti-tumor immune microenvironment in the Sonic Hedgehog subclass of medulloblastoma | Emory University / Anna Kenney, PhD | Innovation Grants | 2019 | Georgia |
Dual PTK7/GD2 Gamma Delta CAR T Cell Therapy for Neuroblastoma | Emory University / Kelly Goldsmith, MD & H. Trent Spencer, PhD & Chris B. Doering, PhD | Reach Grants | 2021 | Georgia |
The YB1 Way of Surviving Radiation, Pediatric Brain Tumor Resistance and Recurrence | Emory University / Abhinav Dey, PhD | Young Investigator Grants | 2015 | Georgia |
Empowering specificity of AML immunotherapies by HSC engineering | Aflac Cancer Center and Blood Disorders Service of Children’s Healthcare of Atlanta / Pietro Genovese | Catalyst Grants | 2023 | Georgia |
Molecular Mechanism and Development of Therapeutic Strategies Targeting MYCN-induced Calcium Signaling in Advanced Neuroblastoma | University of Hawaii at Hilo / Ingo Koomoa-Lange, PhD | Young Investigator Grants | 2014 | Hawaii |
DFMO-based combination therapy for the treatment of advanced stage neuroblastoma. | Cancer Research Center of Hawaii / Dana-Lynn Koomoa | Young Investigator Grants | 2009 | Hawaii |
Theranostics in Children and Young Adults | University of Iowa / Sue O'Dorisio, MD, PhD | Springboard Grants | 2013 | Iowa |
Therapeutic Targeting of Childhood Leukemia by Pharmacological Inhibition of Proteolytic Cleavage of MLL1 | Northwestern University (Illinois) / Zibo Zhao, PhD | Young Investigator Grants | 2018 | Illinois |
Increasing the Availability and Quality of Early Phase Clinical Trials Through the Addition of a Specialized Pediatric Advanced Nurse Practitioner | Children’s Memorial Hospital / Stewart Goldman | Phase I/II Infrastructure Grants | 2008 | Illinois |
Predicting and Overcoming Resistance to Immunotherapy in Pediatric High-Grade Glioma | Ann & Robert H. Lurie Children’s Hospital of Chicago / Oren Becher, MD & Robert Wechsler-Reya, PhD | Innovation Grants | 2019 | Illinois |
The Impact of Hypoxia on Epigenetic Changes in Neuroblastoma | University of Chicago / Sakshi Uppal, PhD | Young Investigator Grants | 2017 | Illinois |
Racial and Ethnic Disparities in Survival of Children with Neuroblastoma | University of Chicago / Susan Cohn, MD | Innovation Grants | 2011 | Illinois |
Genomic and nuclear organizational changes in chemotherapy-resistant rhabdomyosarcoma cells | Ann & Robert H. Lurie Children’s Hospital of Chicago / Kyle MacQuarrie, MD/PhD | 'A' Award Grants | 2023 | Illinois |
Circulating Tumor Biomarkers: New Paradigms for Management of Neuroblastoma | University of Chicago / Mark Applebaum, PhD | 'A' Award Grants | 2021 | Illinois |
Epigenetic Targeted Therapy and Resistance in Pediatric Rhabdoid Tumor | Ann & Robert H. Lurie Children’s Hospital of Chicago / Rintaro Hashizume, MD/PhD | Reach Grants | 2018 | Illinois |
DNA Methylation Inhibitor Therapy for Testicular Germ Cell Tumors | University of Illinois, Urbana-Champaign / Michael Spinella, Ph.D. | Reach Grants | 2014 | Illinois |
Genome-Wide 5hmC Profiling of Neuroblastoma Tumors and Patient Cell-Free DNA | University of Chicago / Susan Cohn, MD & Chuan He PhD | Innovation Grants | 2017 | Illinois |
An Oncolytic Herpes Simplex Virus Restricted in Entry to Neuroblastoma Cells | Northwestern University Medical School / Richard Longnecker, PhD | Innovation Grants | 2013 | Illinois |
DNA Sequencing Using Malaria Slides | Indiana University / Terry Vik, MD | Epidemiology Grants | 2015 | Indiana |
MDM2 as an Effector of Hedgehog Signaling in Brain Development and Medulloblastoma | Purdue University / Susan Mendrysa, PhD | Young Investigator Grants | 2008 | Indiana |
Development of a Connectedness with Healthcare Providers Scale for Adolescents and Young Adults with Cancer | Indiana University / Celeste Phillips-Salimi | Nurse Researcher Grants | 2011 | Indiana |
Childhood Leukemia in Kenya Identified Through Malaria Slide Review | Indiana University / Terry Vik | Epidemiology Grants | 2012 | Indiana |
The Therapy-Related Symptom Checklist for Children (TRSC-C): Systematic Monitoring of Symptoms to Improve Oncology Interventions. | Kansas Medical Center Research Institute, Inc. / Phoebe Williams | Nurse Researcher Grants | 2008 | Kansas |
The Interplay Between Histone Mutations and Replication Stress in Shaping Glioma Phenotypes | Dana-Farber Cancer Institute / Pratiti Bandopadhayay, PhD | 'A' Award Grants | 2021 | Massachusetts |
Genetic Regulators of ER Stress-induced Apoptosis in Pediatric Malignancies | Dana-Farber Cancer Institute / Ujwal Pyati | Young Investigator Grants | 2009 | Massachusetts |
Inhibition of translation initiation as a novel therapeutic strategy against MYCN-amplified neuroblastoma | Dana-Farber Cancer Institute / Rani George, MD, PhD | Innovation Grants | 2022 | Massachusetts |
Targeting the Mechanism of Differentiation Arrest in a Novel Model of Acute Leukemia | Massachusetts General Hospital / David Sykes | Young Investigator Grants | 2011 | Massachusetts |
Tyrosine Kinase Mutation Discovery in Neuroblastoma. | Dana-Farber Cancer Institute / Matthew Meyerson, MD, PhD | Innovation Grants | 2006 | Massachusetts |
Understanding and Preventing Healthy Tissue Damage in Pediatric Cancer Patients | Dana-Farber Cancer Institute / Kristopher Sarosiek, PhD | Young Investigator Grants | 2014 | Massachusetts |
SETD2 Mutations in Prognosis and Chemotherapy Resistance in Relapsed Acute Lymphoblastic Leukemia | Dana-Farber Cancer Institute / Brenton Mar, MD, PhD | Young Investigator Grants | 2014 | Massachusetts |
Modeling RUNX1-Associated Clonal Hematopoietic Disorders in Zebrafish | Boston Children’s Hospital / Leonard Zon, MD | RARE Grant Program (Research Accelerating RUNX1 Exploration) | 2016 | Massachusetts |
Searching for genetic vulnerabilities in osteosarcoma through genome-wide RNAi screening | Dana-Farber Cancer Institute / Stuart Orkin, MD | Innovation Grants | 2012 | Massachusetts |
Blocking the Evil Messenger in MYCN-driven High-risk Neuroblastoma | Boston University / Hui Feng, Md, PhD | Innovation Grants | 2022 | Massachusetts |
Translating BET Bromodomain Inhibitors for Acute Myeloid Leukemia Therapy | Dana-Farber Cancer Institute / Yana Pikman, MD | Young Investigator Grants | 2014 | Massachusetts |
Molecular Basis of ALK Inhibition Resistance in High-risk Neuroblastoma | Dana-Farber Cancer Institute / David Debruyne, PhD | Young Investigator Grants | 2016 | Massachusetts |
Targeting the ETS Transcription Factor Rearrangement EWS/FLI in Ewing sarcoma | Dana-Farber Cancer Institute / Kimberly Stegmaier, MD | Bridge Grants | 2012 | Massachusetts |
Development of a childhood leukemia translational research program. | Dana-Farber Cancer Institute / Lewis Silverman | Phase I/II Infrastructure Grants | 2009 | Massachusetts |
Exploiting a Novel DNA Repair Defect in Ewing Sarcoma | Dana-Farber Cancer Institute / Shuhei Asada, MD/PhD | Young Investigator Grants | 2024 | Massachusetts |
Investigating phase separated condensates in FPD to MDS/AML progression | Broad Institute / Zuzana Tothova, MD/PhD | RUNX1 Early Career Investigator Grants | 2019 | Massachusetts |
Hematopoietic stem cell function in familial platelet disorder therapy | University of Massachusetts Medical School / Lucio Castilla, PhD | Innovation Grants | 2021 | Massachusetts |
GeneEditing in T cell Leukemia to Promote Immunomodulatory Forms of Cell Death | Boston Children’s Hospital / Dr. Ben Croker, PhD | Innovation Grants | 2016 | Massachusetts |
Targeting Chromatin Remodeling Complexes for Rhabdomyosarcoma (RMS) Therapy | Dana-Farber Cancer Institute / Jun Qi, PhD | Innovation Grants | 2023 | Massachusetts |
CDK8 as a New Therapeutic Target in Alveolar Rhabdomyosarcoma | Dana-Farber Cancer Institute / Susu Zhang, PhD | Young Investigator Grants | 2023 | Massachusetts |
Identifying Mechanisms of Glucocorticoid Resistance in Pediatric Acute Lymphoblastic | University of Massachusetts Medical School / Michelle Kelliher, PhD | Innovation Grants | 2015 | Massachusetts |
Epigenetic regulation of genomic instability and its therapeutic implications in T-cell acute lymphoblastic leukemia | Dana-Farber Cancer Institute / Birgit Knoechel, MD/PhD | Innovation Grants | 2019 | Massachusetts |
Role of LMO1 in Neuroblastoma Initiation and Maintenance: Analysis in the Zebrafish model of Childhood Neuroblastoma | Dana-Farber Cancer Institute / Thomas Look, M.D. | Innovation Grants | 2014 | Massachusetts |
Investigating the role of lin-28 in germ cell tumorigenesis | Boston Children’s Hospital / George Daley | Innovation Grants | 2009 | Massachusetts |
Dissecting the Contribution and Inheritance of Germline DNA Damage Repair Gene Mutations in Neuroblastoma | Dana-Farber Cancer Institute / Riaz Gillani, MD | Young Investigator Grants | 2021 | Massachusetts |
A mouse model of Wilms' Tumor | Massachusetts General Hospital / Nabeel Bardeesy, PhD | Young Investigator Grants | 2008 | Massachusetts |
Modeling the Multi-hit Pathogenesis of t(12;21) Associated Pediatric ALL by CRISPR/Cas-mediated Genome Engineering | Massachusetts General Hospital / Hanno Hock, M.D., Ph.D. | Innovation Grants | 2014 | Massachusetts |
Investigating the Role of Circadian Rhythm in the Progression of Acute Myeloid Leukemia | Boston Children’s Hospital / Samantha Morris, PhD | Young Investigator Grants | 2013 | Massachusetts |
Identification of Novel Treatment Targets by Exploring the Interaction of Rhabdomyosarcoma-Associated Oncogenes with Cellular Context in a Mouse Model of Rhabdomyosarcoma | Dana-Farber Cancer Institute / Simone Hettmer | Young Investigator Grants | 2010 | Massachusetts |
SWI/SNF Complex and Glucocorticoid Resistance in Pediatric Acute Lymphoblastic Leukemia | Dana-Farber Cancer Institute / Jennifer Wu | Young Investigator Grants | 2012 | Massachusetts |
In vivo Analysis of Neuroblastoma Pathogenesis using Transgenic Zebrafish | Dana-Farber Cancer Institute / Alfred Tom Look, MD | Innovation Grants | 2011 | Massachusetts |
Novel Approaches to AML Differentiation Therapy | Dana-Farber Cancer Institute / Andrew Lane, MD/PhD | 'A' Award Grants | 2017 | Massachusetts |
The Impact Of CD56neg NK Cells in the Pathogenesis of Endemic Burkitt Lymphoma | University of Massachusetts Medical School / Catherine Forconi, PhD | Young Investigator Grants | 2019 | Massachusetts |
Resistance and Develop Improved Treatments for Relapsed/refractory Pediatric ALL | Dana-Farber Cancer Institute / Elizabeth Townsend, PhD | Young Investigator Grants | 2016 | Massachusetts |
Identification and validation of new therapeutic targets in pediatric leukemia through an aneuploidy-based synthetic lethality screen | Dana-Farber Cancer Institute / David Pellman, MD | Innovation Grants | 2012 | Massachusetts |
Development of Targeted Leukemia Inhibitors Using Nanoparticle Delivery | University of Massachusetts Medical School / Lucio Castilla, Ph.D. | Innovation Grants | 2014 | Massachusetts |
Novel Nanoscale Phosphoproteomic Discovery of Therapeutic Targets in AML Stem Cells | Dana-Farber Cancer Institute / Leo Wang, MD, PhD | Young Investigator Grants | 2015 | Massachusetts |
Identification of New Therapeutic Targets in Pediatric Acute Lymphoblastic Leukemia Through Mosaic Trisomy and Aneuploidy-Based Synthetic Lethality Screens | Dana-Farber Cancer Institute / David Pellman | Innovation Grants | 2010 | Massachusetts |
Identification of proteins interacting with ALK in neuroblastoma. | Dana-Farber Cancer Institute / Rani George | Young Investigator Grants | 2009 | Massachusetts |
3-D Printed Self-fitting Shape Memory Bone Grafts for Smart Pediatric Skeletal Reconstruction | University of Massachusetts Medical School / Jie Song, PhD | Innovation Grants | 2017 | Massachusetts |
Redefining the Cellular Architecture of Diffuse Intrinsic Pontine Glioma through Large-Scale Single-cell RNA-seq Analyses | Massachusetts General Hospital / Mario Suva, MD/PhD | Innovation Grants | 2016 | Massachusetts |
Molecular circuitry of fibrolamellar carcinoma | Massachusetts General Hospital / Nabeel Bardeesy, PhD | Innovation Grants | 2022 | Massachusetts |
Elucidating Mechanisms Driving Renal Medullary Carcinomas to Deliver a Rational Approach to Cancer Directed Therapy | Dana-Farber Cancer Institute / Andrew Hong, MD | Young Investigator Grants | 2015 | Massachusetts |
A Role for Non-canonical Wnt/PCP Signaling in Growth and Self-Renewal of Embryonal Rhabdomyosarcoma | Massachusetts General Hospital / Madeline Hayes, PhD | Young Investigator Grants | 2016 | Massachusetts |
Mechanisms of CNOT3 Tumor Suppression in T-ALL and Identification of New Drugs That Specifically Kill CNOT3-Deficient T-ALL Cells | Dana-Farber Cancer Institute / Zhaodong Li, PhD | Young Investigator Grants | 2014 | Massachusetts |
The role of vitamin D in hepatoblastoma formation and prevention | Brigham and Women's Hospital / Wolfram Goessling, MD/PhD | Innovation Grants | 2012 | Massachusetts |
Stapled Peptide PROTAC: A 3-in-1 Treatment for Pediatric Solid Tumors | Dana-Farber Cancer Institute / Loren Walensky, MD/PhD | Reach Grants | 2021 | Massachusetts |
Targeted nanoparticle-mediated “cold”-to-“hot” reprogramming of the tumor microenvironment of high-risk neuroblastoma | University of Massachusetts Chan Medical School / Prabhani Atukorale, PhD & Jason Shohet, MD, PhD | Innovation Grants | 2022 | Massachusetts |
The Role of Prmt1 in Osteosarcoma Initiation and Metastasis | Dana-Farber Cancer Institute / Hao-Ru Hsu, PhD | Young Investigator Grants | 2013 | Massachusetts |
A Translational Approach to Identify Drugs with Specific Activity Against EZH2 Mutant High Risk T-ALLs and ETP ALLs that Overexpress the JDP2 bZIP Transcription Factor | Dana-Farber Cancer Institute / Shuning He, PhD | Young Investigator Grants | 2015 | Massachusetts |
Discovery of New Targets and Pathways for T-ALL Therapy | Dana-Farber Cancer Institute / Thomas Look | Bridge Grants | 2012 | Massachusetts |
Divergent Core Transcriptional Regulatory Circuitries to Highlight Context-Specific Vulnerabilities in AML | Dana-Farber Cancer Institute / Maxim Pimkin, MD/PhD | Young Investigator Grants | 2018 | Massachusetts |
Development of RADARS-based Therapy to Treat Fusion Molecule Driven Pediatric Malignancies | Boston Children’s Hospital / Alan B. Cantor, MD, PhD | Innovation Grants | 2023 | Massachusetts |
Therapeutically Targeting a Tumor Suppressor Complex in Aggressive Pediatric Cancers | Dana-Farber Cancer Institute / Charles Roberts, MD, PhD | Innovation Grants | 2013 | Massachusetts |
Novel mechanisms and therapeutic targeting of chemoresistant rhabdomyosarcoma | Massachusetts General Hospital / Yueyang Wang, PhD | Young Investigator Grants | 2024 | Massachusetts |
PRL3 as a Novel Therapeutic Target for Relapsed T-cell Acute Lymphoblastic Leukemia | Massachusetts General Hospital / Jessica Blackburn, PhD | Young Investigator Grants | 2013 | Massachusetts |
Regulation of Hematopoietic Stem Cell Engraftment by the Endothelial Cell Niche | Boston Children’s Hospital / Bradley Blaser, MD, PhD | Young Investigator Grants | 2015 | Massachusetts |
The Role of Metabolism in MLL-AF9 Leukemia Initiation | Massachusetts General Hospital / Rushdia Yusuf | Young Investigator Grants | 2010 | Massachusetts |
Dana-Farber/Children’s Hospital Cancer Center Developmental Therapeutics Center of Excellence | Dana-Farber Cancer Institute / Steven DuBois, MD & Wendy London, PhD - Scholars: Melissa Burns, MD; Kevin Campbell, MD; Natalie Collins, MD/PhD; David Shulman, MD | Center of Excellence Grants | 2012 | Massachusetts |
Identifying Therapeutic Vulnerabilities in Pediatric AML through Investigation of the MECOM Transcriptional Network | Boston Children’s Hospital / Richard Voit, MD/PhD | Young Investigator Grants | 2023 | Massachusetts |
Targeting symmetric division in pediatric cancers | Dana-Farber Cancer Institute / Rosalind Segal, MD/PhD | Innovation Grants | 2019 | Massachusetts |
Choline Kinase and Alkylating Agent Resistance in Refractory Childhood Leukemias | Boston Children’s Hospital / Alejandro Gutierrez, MD | Innovation Grants | 2021 | Massachusetts |
Cooperating Genes for inv16 Acute Myeloid Leukemia | University of Massachusetts Medical School / Lucio Castilla | Bridge Grants | 2012 | Massachusetts |
Novel Therapeutic Targets in Relapse T-cell Acute Lymphoblastic Leukemia | Massachusetts General Hospital / David Langenau, PhD | Innovation Grants | 2013 | Massachusetts |
Elucidating the Roles of Aneuploidy in Down Syndrome-Associated Leukemia | Boston Children’s Hospital / Chun-Chin Chen, PhD | Young Investigator Grants | 2023 | Massachusetts |
Therapeutic Reactivation of p53 to Overcome Apoptotic Resistance in Pediatric Leukemia | Dana-Farber Cancer Institute / Loren Walensky, MD, PhD & Kimberly Stegmaier, MD | Reach Grants | 2015 | Massachusetts |
Dissecting Functional uORFs as a Source of Cancer Genes in High-Risk Medulloblastoma | Dana-Farber Cancer Institute / John Prensner, MD/PhD | Young Investigator Grants | 2021 | Massachusetts |
A Role for Notch in Self-renewal in Embryonal Rhabdomyosarcoma | Massachusetts General Hospital / Myron Ignatius, PhD | 'A' Award Grants | 2012 | Massachusetts |
Single-cell Atlas of Pediatric Osteosarcoma | Dana-Farber Cancer Institute / Natalie Collins, MD/PhD | Single-cell Pediatric Cancer Atlas Grant | 2019 | Massachusetts |
TLE1 Tumor Suppressor as a Key Regulator of myc Induced Leukemia | Massachusetts General Hospital / Selvi Ramasamy | Young Investigator Grants | 2010 | Massachusetts |
Dissecting the Role of FOXR2 in the Oncogenesis of Diffuse Intrinsic Pontine Glioma | Dana-Farber Cancer Institute / Jessica Tsai, MD/PhD | Young Investigator Grants | 2020 | Massachusetts |
Targeting MYC/MYCN-driven Transcriptional Amplification in Pediatric Cancer | Dana-Farber Cancer Institute / Rani George, M.D., Ph.D. | Innovation Grants | 2014 | Massachusetts |
Genetic Dissection of Trisomy 21-TMD Using Human Pluripotent Stem Cells | Boston Children’s Hospital / Glenn MacLean | Young Investigator Grants | 2013 | Massachusetts |
Selective inhibition of nuclear export as a novel therapeutic strategy in AML | Dana-Farber Cancer Institute / Julia Etchin | Young Investigator Grants | 2012 | Massachusetts |
Reversing mSWI/SNF (BAF) Complex Misassembly and Genomic Targeting in Human Synovial Sarcoma | Dana-Farber Cancer Institute / Cigall Kadoch, PhD | 'A' Award Grants | 2017 | Massachusetts |
Transcriptional Effectors of Activated RAS Signaling in Juvenile Myelomonocytic Leukemia | Boston Children’s Hospital / Alan Cantor, MD, PhD | Innovation Grants | 2015 | Massachusetts |
Identification and Validation of Differentiation Therapy for Osteosarcoma | Dana-Farber Cancer Institute / Katherine Janeway, MD | Young Investigator Grants | 2008 | Massachusetts |
Targeting the Rac GTPase Pathway to Sabotage RAS Signaling in RAS-mutated Leukemia | Boston Children’s Hospital / Sara Canovas Nunes, PhD | Young Investigator Grants | 2020 | Massachusetts |
Understanding the Mechanisms of HOX Gene Regulation in Normal and Leukemic Hematopoietic Stem Cells to Identify New Therapies for Pediatric AML | Boston Children’s Hospital / Anne Robertson, PhD | Young Investigator Grants | 2017 | Massachusetts |
Characterizing Inflammatory Phenotypes Associated with RUNX1 Deficiency | Dana-Farber Cancer Institute / Waihay Wong, MD/PhD | RUNX1 Early Career Investigator Grants | 2021 | Massachusetts |
Olfactory Ensheathing Cells for Pediatric Glioma Gene/Cell Therapy | Massachusetts General Hospital / Bakhos Tannous, PhD | Innovation Grants | 2018 | Massachusetts |
Empowering specificity of AML immunotherapies by HSC engineering | Boston Children’s Hospital / Pietro Genovese | Catalyst Grants | 2023 | Massachusetts |
Mechanisms of OTX2 Mediated Chromatin Regulation in Medulloblastoma | Massachusetts General Hospital / Miguel Rivera, MD | Innovation Grants | 2017 | Massachusetts |
The Role of DEF and SSU Processome in Neuroblastoma Pathogenesis | Dana-Farber Cancer Institute / Ting Tao, PhD | Young Investigator Grants | 2015 | Massachusetts |
Pharmacologic Enhancement of Residual Wild Type RUNX1 Protein Activity in FPD/AML | Boston Children’s Hospital / Alan Cantor, MD, PhD | RARE Grant Program (Research Accelerating RUNX1 Exploration) | 2016 | Massachusetts |
Modeling GATA2 Associated MDS/AML Predisposition Syndrome Using Color-Barcoding and Mutagenesis in Zebrafish | Dana-Farber Cancer Institute / Serine Avagyan, PhD | Young Investigator Grants | 2018 | Massachusetts |
Modeling familial platelet disorder associated RUNX1 mutations in mice | University of Massachusetts Medical School / Lucio Castilla, PhD | RARE Grant Program (Research Accelerating RUNX1 Exploration) | 2020 | Massachusetts |
Targeting the Metabolic Drivers of Chemo Resistance in Acute Myeloid Leukemia | Harvard University / Nick van Gastel, PhD | Young Investigator Grants | 2018 | Massachusetts |
Targeted Therapy for Core Binding Factor Leukemia | University of Massachusetts Medical School / John Pulikkan, PhD | Young Investigator Grants | 2014 | Massachusetts |
Histone Modification and Hmgn1 Overexpression as Drivers of B-ALL with Polysomy 21 | Dana-Farber Cancer Institute / Andrew Lane, MD, PhD | Young Investigator Grants | 2013 | Massachusetts |
Anti-Angiogenic (Metronomic) Chemotherapy in Children with Poor Prognosis. | Dana-Farber Cancer Institute / Mark Kieran, MD, PhD | Innovation Grants | 2006 | Massachusetts |
Web-Based Cognitive-Behavioral Treatment for Insomnia in Adolescent Cancer Survivors | Dana-Farber Cancer Institute / Eric Zhou, PhD | Psychosocial Grants | 2016 | Massachusetts |
Reactivating Apoptosis in Refractory Pediatric Cancer by Molecular Inhibition of MCL-1 | Dana-Farber Cancer Institute / Loren Walensky, MD, PhD | Innovation Grants | 2013 | Massachusetts |
Unraveling GABAergic interneuron-like lineage in H3G34-mutant hemispheric high-grade gliomas: their impact on network formation and invasion | Dana-Farber Cancer Institute / Gustavo Alencastro Veiga Cruzeiro, PhD | Young Investigator Grants | 2024 | Massachusetts |
MYC-driven Core Regulatory Circuits in Neuroblastoma | Dana-Farber Cancer Institute / Mark Zimmerman, PhD | Young Investigator Grants | 2018 | Massachusetts |
Targeted Inhibition of Lin28/let-7 Binding to Treat Pediatric Malignancy | Boston Children’s Hospital / George Q. Daley, MD/PhD | Innovation Grants | 2016 | Massachusetts |
Stapled Oncolytic Peptides for Treatment-Resistant Pediatric Leukemias | Dana-Farber Cancer Institute / Loren Walensky, MD, PhD | Innovation Grants | 2023 | Massachusetts |
Targeting BRD9 in Sarcoma | Dana-Farber Cancer Institute / Scott Armstrong, MD/PhD | Innovation Grants | 2017 | Massachusetts |
Targeted nanoparticle-mediated “cold”-to-“hot” reprogramming of the tumor microenvironment of high-risk neuroblastoma | University of Massachusetts Amherst / Prabhani Atukorale, PhD & Jason Shohet, MD, PhD | Innovation Grants | 2022 | Massachusetts |
Dissecting Microenvironmental Interactions in Pediatric High-Grade Gliomas that Promote Tumor Growth | Dana-Farber Cancer Institute / Mariella G. Filbin, MD/PhD | Crazy 8 Pilots | 2019 | Massachusetts |
Mechanisms of BRAF Activation in KIAA1549-BRAF Mutant pLGGs | Broad Institute / Sean Misek, PhD | Young Investigator Grants | 2023 | Massachusetts |
Therapies for SHH-subtype Medulloblastoma | Dana-Farber Cancer Institute / Rosalind Segal, M.D., Ph.D. | Innovation Grants | 2014 | Massachusetts |
Accessing Combinatorial Effect of PARP Inhibitor with DNA Damaging Agent in Rhabdomyosarcoma at Single Cell Resolution | Massachusetts General Hospital / Chuan Yan, PhD | Young Investigator Grants | 2018 | Massachusetts |
Regulation of Tumor Debris Mediated Inflammation as a Therapeutic Modality in Medulloblastoma | Dana-Farber Cancer Institute / Mark Kieran, MD, PhD & Dipak Panigrahy, MD | Innovation Grants | 2015 | Massachusetts |
Investigating the impact of osteosarcoma genetic lesions on bone differentiation | Dana-Farber Cancer Institute / James Morrow, MD/PhD | Young Investigator Grants | 2024 | Massachusetts |
The Role of PARP3 in the Formation of Chromosomal Translocations | Dana-Farber Cancer Institute / Tovah Day, PhD | Young Investigator Grants | 2015 | Massachusetts |
Selectively targeting EP300 with small molecules for neuroblastoma (NB) therapy | Dana-Farber Cancer Institute / Jun Qi, PhD | Innovation Grants | 2019 | Massachusetts |
Targeting the biological underpinnings of pulmonary metastasis in osteosarcoma | Dana-Farber Cancer Institute / Rani George, MD/PhD | Crazy 8 Awards | 2022 | Massachusetts |
Correction of Hematopoietic Defects in Down Syndrome by Chromosome 21 Silencing | University of Massachusetts Medical School / Peter Newburger, M.D. | Innovation Grants | 2014 | Massachusetts |
Multifunctional Nanomaterials for the Prevention of Radiotherapy's Side Effects and Childhood Cancers | Massachusetts General Hospital / Charalambos Kaittanis, PhD | Young Investigator Grants | 2013 | Massachusetts |
Identifying Epigenetic Mechanisms Impacting Neuroblastoma Genome Stability and Drug Response | Massachusetts General Hospital / Johnathan Whetstine, PhD | Innovation Grants | 2015 | Massachusetts |
Development of a Childhood Leukemia Translational Research Program | Dana-Farber Cancer Institute / Lewis Silverman | Phase I/II Infrastructure Grants | 2011 | Massachusetts |
Targeting Oncogenic RAS in Pediatric Leukemia | Dana-Farber Cancer Institute / Loren Walensky, MD/PhD | Innovation Grants | 2018 | Massachusetts |
Exploiting the Differentiation Potential of Pediatric High-Grade Glioma to Discover Novel Therapeutic Opportunities | Dana-Farber Cancer Institute / Mariella Filbin, MD/PhD | 'A' Award Grants | 2019 | Massachusetts |
Pediatric Oncology Clinical Research Infrastructure | Dana-Farber Cancer Institute / Lisa Diller, MD | Phase I/II Infrastructure Grants | 2007 | Massachusetts |
Investigating the Role of Lin-28 in Germ Cell Tumorigenesis | Boston Children’s Hospital / George Daley, MD/PhD | Innovation Grants | 2011 | Massachusetts |
Targeted Hyperactivation of PI3K/AKT in B-cell malignancies | Dana-Farber Cancer Institute / Vishal Khairnar, PhD | Young Investigator Grants | 2019 | Massachusetts |
Investigating the Role of the RNA Binding Protein LIN28 in Neuroblastoma | Boston Children’s Hospital / John Powers | Young Investigator Grants | 2012 | Massachusetts |
Novel Strategy for Reducing Radiation-Induced Morbidity and Treating Recurrent Medulloblasoma | Massachusetts General Hospital / Rakesh Jain, PhD | Reach Grants | 2013 | Massachusetts |
Using zebrafish to model the molecular origins of pediatric myeloid malignancies and acute myeloid leukemia | Dana-Farber Cancer Institute / Evisa Gjini | Young Investigator Grants | 2011 | Massachusetts |
Development of a Screening Module to Assess Sibling-Related Psychosocial Risk in Families of Children with Cancer | Boston University / Kristin Long, PhD | Psychosocial Grants | 2014 | Massachusetts |
Identifying Disease Mechanisms and Therapeutic Opportunities in Pediatric Low-grade Gliomas Driven by MYB-QKI Fusions | Dana-Farber Cancer Institute / Cecile Rouleau, PhD | Young Investigator Grants | 2017 | Massachusetts |
Barcoding Pediatric Leukemia for Therapeutic Purposes | Boston Children’s Hospital / Leonard Zon, MD | Crazy 8 Awards | 2020 | Massachusetts |
Characterizing Resistance Mechanisms to BET-Bromodomain Inhibition in MYC-amplified | Broad Institute / Rameen Beroukhim, MD,PhD | Innovation Grants | 2015 | Massachusetts |
The Role of ARID1A in Neuroblastoma Pathogenesis | Dana-Farber Cancer Institute / Hui Shi, PhD | Young Investigator Grants | 2016 | Massachusetts |
Role of N6-Methyladenosine (m6A) mRNA Modification Pathway in Neuroblastoma | Boston Children’s Hospital / Shuibin Lin, PhD | Young Investigator Grants | 2017 | Massachusetts |
Identification of FDA approved drugs with anti-tumor activity in rhabdomyosarcoma. | Massachusetts General Hospital / David Langenau | Young Investigator Grants | 2009 | Massachusetts |
Characterization of Novel OTX2-semaphorin Gene Signaling Pathways Regulating the ‘Grow and Go’ Arms of Highly Aggressive Medulloblastomas | University of Manitoba / Tamra Werbowetski-Ogilvie, PhD | Innovation Grants | 2017 | Manitoba |
The Role of PASG in Mediating Epigenetic Change and Outcome in AML. | The Johns Hopkins University School of Medicine / Jason Farrar, MD | Young Investigator Grants | 2007 | Maryland |
HMG-I/Y in Pediatric Leukemia and Lymphoma | The Johns Hopkins University School of Medicine / Linda Smith Resar, MD | Innovation Grants | 2008 | Maryland |
Targeted Inhibition of the DNA Damage Response Pathway: A Novel Intervention in the Treatment of Pediatric Leukemias | National Cancer Institute / Andre Nussenzweig, Ph.D. | Reach Grants | 2014 | Maryland |
Epigenetic Regulation of T cell Activation and Immunotherapy | The Johns Hopkins University School of Medicine / Brian Ladle, MD, PhD | Young Investigator Grants | 2013 | Maryland |
HMG-I/Y in pediatric Leukemia and Lymphoma. | The Johns Hopkins University School of Medicine / Linda Smith Resar, MD | Innovation Grants | 2006 | Maryland |
Targeting Tumor Suppressor MicroRNAs in Pediatric Acute Lymphoblastic Leukemia | The Johns Hopkins University School of Medicine / Linda Resar, M.D. | Innovation Grants | 2014 | Maryland |
Targeting the Epigenome of Diffuse Intrinsic Pontine Glioma | The Johns Hopkins University School of Medicine / Sama Ahsan, MD | Young Investigator Grants | 2014 | Maryland |
Targeting Neurons in the Osteosarcoma Microenvironment with Non-Opioid Analgesic Lipid Nanoparticles | The Johns Hopkins University School of Medicine / Aaron James, MD, PhD | Innovation Grants | 2023 | Maryland |
Targeting Fusion-driven Sarcomas | National Institutes of Health / Javed Khan, MD | Crazy 8 Pilots | 2019 | Maryland |
Developing a Novel Tumor Model to Screen for New Therapies for Spinal Ependymoma | The Johns Hopkins University School of Medicine / Linda Resar, MD & Richard Schlegel, MD, PhD | Innovation Grants | 2015 | Maryland |
The Cebpa Downstream Enhancer as a Key Target of Transformation to Acute Myeloid Leukemia | The Johns Hopkins University School of Medicine / Stacy Cooper, MD | Young Investigator Grants | 2015 | Maryland |
Practical, Reproducible, and Statistically-Rigorous Workflows for Single-Nucleus Analysis of Childhood Cancer Data | Johns Hopkins Bloomberg School of Public Health / Stephanie C. Hicks, PhD | Crazy 8 Pilots | 2019 | Maryland |
Targeting RNA Helicase DDX3 to Treat Recurrent High Grade Sarcoma | The Johns Hopkins University School of Medicine / David Loeb, MD, PhD | Reach Grants | 2013 | Maryland |
Promoter Hypermethylation in MLL-Rearranged Leukemias: Biology and Therapeutic Targeting | The Johns Hopkins University School of Medicine / Eric Schafer | Young Investigator Grants | 2010 | Maryland |
Targeting HMGA1 in Childhood ALL | The Johns Hopkins University School of Medicine / Amy M. Belton, PhD | Young Investigator Grants | 2011 | Maryland |
Identifying a Therapeutic Partner for TAK228 for Pediatric Phase II Brain Tumor Studies | The Johns Hopkins University School of Medicine / Eric H. Raabe, MD/PhD | Reach Grants | 2018 | Maryland |
Targeting the LIN28 Pathway in ATRT | The Johns Hopkins University School of Medicine / Eric Raabe, MD, PhD | 'A' Award Grants | 2015 | Maryland |
Developing Novel Transcription Factor PROTACs to Disrupt the HMGA1 Epigenome in Relapsed Leukemia | The Johns Hopkins University School of Medicine / Linda Resar, MD and Jian Jin, PhD | Innovation Grants | 2022 | Maryland |
A Developmental Model to Characterize the Epigenetic Origins of the Retinoblastoma Tumor Initiating Cell | The Johns Hopkins University School of Medicine / Jeffrey Huo, MD, PhD | Young Investigator Grants | 2014 | Maryland |
Targeting Spinal Ependymoma and Other Gliomas Using Novel Genetically Defined Models | The Johns Hopkins University School of Medicine / Charles Eberhart, MD, PhD | Catalyst Grants | 2019 | Maryland |
Modeling Pediatric Spinal Gliomas Using Murine Spinal Neural Stem Cells | The Johns Hopkins University School of Medicine / Charles Eberhart, MD/PhD & Eric Raabe MD/PhD | Innovation Grants | 2016 | Maryland |
An Exploration of the Medulloblastoma and Glioblastoma Genomes: A Critical Analysis of Candidate Cancer Genes as Potential Molecular Targets for Diagnostics and Therapeutics | The Johns Hopkins University School of Medicine / Will Parsons, MD, PhD | Young Investigator Grants | 2007 | Maryland |
Circadian Rhythms, Fatigue and Bright Light Therapy in Adolescent Cancer Survivors | University of Maryland, College Park / Valerie E. Rogers, PhD | Nurse Researcher Grants | 2015 | Maryland |
Targeting Glutamine Metabolism in MYC Driven Atypical Teratoid Rhabdoid Tumors | The Johns Hopkins University School of Medicine / Jeffrey Rubens, MD | Young Investigator Grants | 2017 | Maryland |
Targeting HMGA1 in Pediatric T-cell Acute Lymphoblastic Leukemia | The Johns Hopkins University School of Medicine / Joelle Hillion, PhD | Young Investigator Grants | 2008 | Maryland |
Donor T-Cell DNA Methylation in GVHD and the Graft-vs-Tumor Effect after Allogeneic Hematopoietic Stem Cell Transplant | The Johns Hopkins University School of Medicine / Yiouli Panayiota Ktena, MD | Young Investigator Grants | 2020 | Maryland |
Exploring a novel immunotherapy: cooperation of endogenous CD8+ t-cells and exogenous, allogeneic CD4+ t-cells. | The Johns Hopkins University School of Medicine / Heather Symons | Young Investigator Grants | 2009 | Maryland |
Identification of Alveolar Rhabdomyosarcoma "Achilles' Heel" | National Cancer Institute / Fernanda Arnaldez | Young Investigator Grants | 2011 | Maryland |
Modeling H3 G34R and BCOR-Altered Glioma Pathogenesis Using Neural Stem Cells | The Johns Hopkins University School of Medicine / Satoshi Nakata, MD/PhD | Young Investigator Grants | 2019 | Maryland |
The Role of Inhibition of Apoptosis by C/EBPalpha and C/EBPalpha oncoproteins in AML. | The Johns Hopkins University School of Medicine / Ido Paz-Priel, MD | Young Investigator Grants | 2007 | Maryland |
Development of the Next Generation FLT3 Inhibitors for Pediatric AML and Infant ALL | The Johns Hopkins University School of Medicine / Donald Small, MD, PhD | Innovation Grants | 2012 | Maryland |
Genetic Alterations in Intramedullary Spinal Cord Tumors | The Johns Hopkins University School of Medicine / George Jallo, MD | Innovation Grants | 2013 | Maryland |
Targeting the Thymic Stromal Lymphopoeitin Receptor Signaling Axis to Reduce Relapse of High Risk Pediatric Acute Lymphoblastic Leukemia | National Cancer Institute / Christopher Chien, PhD | Young Investigator Grants | 2014 | Maryland |
A Home Physical Activity Program to Improve Cognitive Late Effects in Children Treated with Radiation for Brain Tumors | National Cancer Institute / Pamela Wolters, PhD | Psychosocial Family Impact Grant | 2017 | Maryland |
Pre-clinical Testing of Novel Glutamine Metabolic Inhibitors in MYC-driven Medulloblastoma | The Johns Hopkins University School of Medicine / Eric Raabe, MD/PhD & Dr. Barbara Slusher, PhD | Innovation Grants | 2016 | Maryland |
Converting the Glioblastoma Multiforme Tumor-Associated Macrophage Phenotype | The Johns Hopkins University School of Medicine / Alan D. Friedman, M.D. | Innovation Grants | 2014 | Maryland |
Identification of Mechanisms of Resistance to Trametinib Monotherapy in PAX-fusion Negative Rhabdomyosarcoma | National Cancer Institute / Marielle Yohe, MD/PhD | Young Investigator Grants | 2016 | Maryland |
Engineering the Lymph Node Environment with Therapeutic Vaccine Depots to Combat Neuroblastoma | University of Maryland, College Park / Christopher Jewell, PhD | 'A' Award Grants | 2013 | Maryland |
Altering master genetic regulators SNF5/INI1 and LIN28A to model and treat atypical teratoid/rhabdoid tumors | The Johns Hopkins University School of Medicine / Eric Raabe | Young Investigator Grants | 2011 | Maryland |
Novel Approaches for Epigenetic Therapy for Relapsed Acute Lymphoblastic Leukemia | The Johns Hopkins University School of Medicine / Linda Resar, MD & Andrei Thomas-Tikhonenko, PhD | Innovation Grants | 2017 | Maryland |
Therapeutic Targeting of the Disrupted Metabolic State in DIPG | University of Michigan / Costas Lyssiotis, PhD & Sriram Venneti, MD/PhD | Innovation Grants | 2019 | Michigan |
Engager T Cells: A Novel Immunotherapeutic for AML | University of Michigan / Challice Bonifant, MD, PhD | Young Investigator Grants | 2015 | Michigan |
Selective Epigenetic Regulation of Notch1 in T-cell Acute Lymphoblastic Leukemia | University of Michigan / Mark Yat-Fung Chiang, MD/PhD | Innovation Grants | 2016 | Michigan |
Development of a Pharmacodynamic Marker of EWS-FLI1 Activity to Aid in the Clinical Translation of Targeted Therapies for Ewing sarcoma | Van Andel Research Institute / Patrick Grohar, MD, PhD | Reach Grants | 2013 | Michigan |
Epigenetic therapies to concurrently target DIPG tumor cells and harness the immune system | The Regents of the University of Michigan / Sriram Venneti, MD/PhD | R Accelerated Award Grants | 2022 | Michigan |
Mechanistic and Therapeutic Development of ATM as a Tumor Cell Selective Target for Radiosensitization in H3K27M DMG | The Regents of the University of Michigan / Meredith Morgan, PhD & Daniel Wahl, MD/PhD | Reach Grants | 2022 | Michigan |
Development of Mithramycin Analogs for Ewing sarcoma | Van Andel Research Institute / Patrick Grohar, MD/PhD | Innovation Grants | 2017 | Michigan |
Unraveling metabolic dependencies in childhood supratentorial ependymomas. | Regents of the University of Michigan / Sriram Venneti, MD/PhD | Innovation Grants | 2021 | Michigan |
HOX Genes As Developmental Regulators Of Sarcomagenesis | University of Michigan / Elizabeth Lawlor, MD/PhD & Deneen Wellik, PhD | Innovation Grants | 2016 | Michigan |
Mechanisms of Oncogenic Transformation by TLX1/HOX11 | University of Michigan / Mark Chiang | Young Investigator Grants | 2011 | Michigan |
Development of Targeted DNA-damaging Therapy for ATRX-deficient Pediatric Glioblastoma | University of Michigan / Carl Koschmann, MD | Young Investigator Grants | 2014 | Michigan |
Mechanisms of leukocyte recruitment to the lung during idiopathic pneumonia syndrome following allogeneic bone marrow transplantation. | Regents of the University of Michigan / Sung Won Choi, MD | Young Investigator Grants | 2006 | Michigan |
Targeting Glutamine Addiction in Diffuse Intrinsic Pontine Gliomas (DIPGs) | University of Michigan / Sriram Venneti, MD/PhD | Innovation Grants | 2018 | Michigan |
Mechanisms of LGR5 Regulation and Function in Ewing sarcoma Metastasis | University of Michigan / Elizabeth Lawlor, M.D., Ph.D. | Innovation Grants | 2014 | Michigan |
Novel Therapy for Pediatric Leukemia Patients with NUP98 Translocations | The Regents of the University of Michigan / Jolanta Grembecka, PhD | Reach Grants | 2022 | Michigan |
Optimization of Drug Efflux and Brain Clearance to Improve CED of Targeted Therapy to H3K27M DMG | Mayo Clinic / David Daniels, MD/PhD | Reach Grants | 2021 | Minnesota |
Mechanisms to Redirect Tumor Associated Macrophages to Target Retinoblastoma Cells | The Regents of the University of Minnesota / Timothy Hallstrom, PhD | Innovation Grants | 2023 | Minnesota |
The Role of PTPRD as a Tumor Suppressor in Neuroblastoma Pathogenesis | Mayo Clinic / Shizhen Zhu, MD, PhD | Young Investigator Grants | 2013 | Minnesota |
Development and Characterization of Novel Models of Human Osteosarcoma Development and Metastasis | University of Minnesota / Beau Webber, PhD | Young Investigator Grants | 2017 | Minnesota |
Yoga for Children and Adolescents After Completing Cancer Treatment | Children’s Health Care / Mary (Casey) Hooke | Nurse Researcher Grants | 2010 | Minnesota |
Phase I and II Clinical Research Program Infrastructure Award | University of Minnesota / Brenda Weigel, MD & Emily Greengard MD | Phase I/II Infrastructure Grants | 2015 | Minnesota |
Genomics of Pediatric Germ Cell Tumors | University of Minnesota / Jenny Poynter, PhD | Epidemiology Grants | 2017 | Minnesota |
Phase I and II Clinical Research Program Infrastructure Award | University of Minnesota / Brenda Weigel, MD, MSc | Phase I/II Infrastructure Grants | 2011 | Minnesota |
KAM: Kids are Moving; An Exercise Program for Children with Cancer | University of Minnesota / Mary Catherine (Casey) Hooke, PhD | Nurse Researcher Grants | 2014 | Minnesota |
Enhancing Pediatric Sarcoma Immunotherapy by Drug Induced Expression of Tumor-Specific Cryptic Neoantigens | University of Minnesota / David Largaespada, PhD | Innovation Grants | 2016 | Minnesota |
Genetic Susceptibility to Ototoxicity in Pediatric Germ Cell Tumor Survivors | University of Minnesota / Jenny Poynter, MPH, PhD | Epidemiology Grants | 2020 | Minnesota |
MLL-based chromosomal translocations in the pathogenesis of childhood leukemia. | Children’s Mercy / Erin Guest | Young Investigator Grants | 2009 | Missouri |
In Vivo Analysis of Early Neuroblastoma Development using Transgenic Quail | Stowers Institute for Medical Research / Paul Kulesa, PhD | Innovation Grants | 2015 | Missouri |
The Regulation of Hematopoietic Stem Cell Function by Granulocyte-Colony Stimulating Factor | Washington University / Laura Schuettpelz, MD, PhD | Young Investigator Grants | 2013 | Missouri |
The Role of Inherited MLL3 Single Nucleotide Variants and Fetal Epigenetic Programming in Infant Leukemogenesis | Washington University / Jeffrey Magee, MD/PhD | 'A' Award Grants | 2016 | Missouri |
Neurofibromatosis Type 1 as a model population for pediatric brain cancer prevention and control research | Washington University / Kimberly Johnson Ph.D. | Epidemiology Grants | 2012 | Missouri |
The Role of Germline Variants in Infant Leukemogenesis | Washington University / Margaret Ferris, MD/PhD | Young Investigator Grants | 2019 | Missouri |
Parent Satisfaction in an Outpatient Pediatric Bone Marrow Transplant Setting | Children’s Mercy / Nancy Shreve | Nurse Researcher Grants | 2010 | Missouri |
Targeting KDM6B in Pediatric Leukemia | Washington University / Grant A. Challen, PhD | Innovation Grants | 2018 | Missouri |
DNA Damage Responses Coordinate Survival and Cell Death Switching In Lymphocytes | Washington University / Jeffrey Bednarski, MD, PhD | 'A' Award Grants | 2013 | Missouri |
Exploring the impact of a teen weekend on the quality of life of the adolescent with cancer: A qualitative, case/control study. | The Children’s Mercy Hospital / Kristin Stegenga, PhD, RN | Nurse Researcher Grants | 2007 | Missouri |
Exosomes as Biomarkers to Monitor Disease Progression and Response to Therapy in Ewing sarcoma | Children’s Mercy / Glenson Samuel, MD | Young Investigator Grants | 2014 | Missouri |
Defining the Molecular Mechanisms Underlying Pediatric Brain Tumor Penetrance | Washington University / Nicole Brossier, MD/PhD | Young Investigator Grants | 2019 | Missouri |
RNA-ECS to Quantify Rare Clonal RNA Species at Diagnosis, Remission and Relapse from the COG AAML1031 Study | Washington University / Todd Druley, MD/PhD | Innovation Grants | 2018 | Missouri |
Developing Personalized (precision) Medicine Strategies to Optimize Pediatric Brain Tumor Management | Washington University / David Gutmann, M.D., Ph.D. | Innovation Grants | 2014 | Missouri |
Palliative Care and End-of-Life Communication Experiences of Pediatric Oncology Nurses. | Goldfarb School of Nursing at Barnes Jewish College of Nursing / Verna Hendricks-Ferguson, PhD | Nurse Researcher Grants | 2007 | Missouri |
Identification of the Molecular Targets of MLL Translocation-Based Childhood Leukemia | Stowers Institute for Medical Research / Ali Shilatifard | Innovation Grants | 2010 | Missouri |
A Genomics Driven Pluripotent Stem Cell Model of Infant Lymphoblastic Leukemia | Children's Mercy Hospital Kansas City / Meagan Vacek, DO | Catalyst Grants | 2023 | Missouri |
Epigenetic Modifiers as Therapeutic Targets in Pediatric T-cell Acute Lymphoblastic Leukemia | Washington University / Grant Challen, PhD | 'A' Award Grants | 2012 | Missouri |
Identification of Risk Factors for Pediatric Brain Tumors in a High Risk Population | Washington University / Kimberly Johnson, PhD, MPH | Epidemiology Grants | 2013 | Missouri |
Identifying Rare Genetic Variants Involved in High Risk Pediatric Leukemia Via Pooled Sequencing | Washington University / Todd Druley, MD, PhD | 'A' Award Grants | 2009 | Missouri |
Enhancing the therapeutic efficacy of chimeric antigen receptor T cells for acute myeloid leukemia | Washington University / Miriam Kim, MD | Young Investigator Grants | 2019 | Missouri |
Therapeutic Potential of the MST1/Hippo Tumor Suppressor Pathway in Alveolar Rhabdomyosarcoma | Duke University / Corinne Mary Linardic, MD, PhD | Innovation Grants | 2013 | North Carolina |
Role of the macro lncRNA KCNQ1OT1 in embryonal rhabdomyosarcoma tumorigenesis | Duke University / Corinne Linardic, MD/PhD | Innovation Grants | 2019 | North Carolina |
Clinical Development of RNA Nanoparticle Vaccines Targeting Recurrent Pediatric Brain Cancers | Duke University / Duane Mitchell, MD, PhD | Innovation Grants | 2011 | North Carolina |
Modeling anaplastic medulloblastoma using cerebellar stem cells | Duke University / Robert Wechsler-Reya, PhD | Innovation Grants | 2009 | North Carolina |
Symptom Patterns during Pediatric Hematopoietic Stem Cell Transplant Recovery | Duke University Medical Center / Cheryl Rodgers, RN, PhD | Nurse Researcher Grants | 2014 | North Carolina |
Targeting Chondroitin Sulphate Proteoglycan 4 (CSPG4) in Glioblastoma | University of North Carolina / Gianpietro Dotti, MD & Barbara Savoldo, MD/PhD | Reach Grants | 2017 | North Carolina |
The Role of MST1 in Non-canonical Hippo Signaling in Rhabdomyosarcoma | Duke University / Lisa Crose, Ph.D. | 'A' Award Grants | 2014 | North Carolina |
Nitrosative Stress And Symptom Severity During Childhood Leukemia Treatment | Duke University Medical Center / Marilyn Hockenberry, RN, PhD | Nurse Researcher Grants | 2013 | North Carolina |
Molecular characterization of OTX2 as a novel therapeutic target. | Duke University Medical Center / Hai Yan, MD | Innovation Grants | 2006 | North Carolina |
Targeting Pediatric Brainstem Glioma with Oncolytic Polioviruses. | Duke University Medical Center / Matthias Gromeier, MD | Innovation Grants | 2006 | North Carolina |
Pathogenesis of T-cell Acute Lymphoblastic Leukemia from Myeloproliferative Disorder | Duke University / Motonari Kondo | Innovation Grants | 2010 | North Carolina |
Metabolic control of p53 activation in T-ALL. | Duke University / Jeffrey Rathmell | Innovation Grants | 2009 | North Carolina |
Pax3-FKHR targets that enable bypass of cellular senescence in rhabdomyosarcoma. | Duke University Medical Center / Corinne Mary Linardic, MD, PhD | Young Investigator Grants | 2006 | North Carolina |
Stroma Biology Identifies Heparin as a Differentiating Agent in Neuroblastoma | Duke University Medical Center / Gerard Blobe, MD, PhD | Reach Grants | 2013 | North Carolina |
Preclinical Development of Atr Inhibitor VE-822, Delivered Systemically in Nanoparticles, for Medulloblastoma Therapy | University of North Carolina / Timothy Gershon, MD, PhD | Innovation Grants | 2015 | North Carolina |
The Role of Mxi1 in the Modulation N-Myc Function in Neuroblastoma | Duke University / Michael Armstrong | Young Investigator Grants | 2011 | North Carolina |
Genetic Susceptibility to Pediatric Osteosarcoma and Interaction with Measures of Childhood Growth | Duke University / Kyle Walsh, Ph.D. | 'A' Award Grants | 2014 | North Carolina |
Arterial Stiffness in Children who Recently Completed Cancer Therapy | University of North Carolina / Sheila Santacroce, PhD | Nurse Researcher Grants | 2013 | North Carolina |
Utilizing chromatin directed inhibitors to regulate gene expression in Ewing sarcoma for therapeutic benefit | University of North Carolina / Justin Sperlazza, MD/PhD | Young Investigator Grants | 2024 | North Carolina |
Modulation of STING to enhance the efficacy of treatments for diffuse midline glioma | Duke University / Zachary Reitman, MD/PhD | 'A' Award Grants | 2023 | North Carolina |
Dissecting the Hierarchy of Tumor Cell Differentiation Using Dual Recombinase Technology in a Novel Mouse Model of Rhabdomyosarcoma | Duke University Medical Center / David Van Mater, MD, PhD | Young Investigator Grants | 2013 | North Carolina |
Synergistic Differentiation Therapy in Neuroblastoma | Duke University / Gerard Blobe, M.D./Ph.D | Innovation Grants | 2015 | North Carolina |
Single-cell Gene Expression and Cytosine Modification Profiling in Pediatric Central Nervous System Tumors | Dartmouth College / Brock Christensen, PhD | Single-cell Pediatric Cancer Atlas Grant | 2019 | New Hampshire |
The role of pyruvate kinase as a therapeutic target in pediatric leukemia | Rutgers Cancer Institute of New Jersey / Daniel Herranz Benito, PhD | R Accelerated Award Grants | 2023 | New Jersey |
De-escalation of Radiotherapy for Medulloblastoma by a Novel DNA Damage Checkpoint Inhibitor | Feinstein Institute for Medical Research - North Shore / Marc Symons, PhD | Innovation Grants | 2017 | New York |
Molecular Regulation of CNS Involvement in Pediatric ALL | New York University School of Medicine / Iannis Aifantis, PhD | Innovation Grants | 2008 | New York |
Immunoglobulin High-Throughput Sequencing for Refining Risk Stratification in Infant B-ALL | University of Rochester / Carol Fries Simpson, MD | Reach Grants | 2023 | New York |
Image Guided Diffuse Intrinsic Pontine Glioma Drug Delivery and Design | Weill Cornell Medical College / Mark Souweidane, MD & Richard Ting, PhD | Innovation Grants | 2016 | New York |
Identification of Rhabdomyosarcoma Therapies Using an Efficient Mouse and Drosophila Repurposing Screen | Memorial Sloan-Kettering Cancer Center / Mary Baylies, Ph.D. | Reach Grants | 2014 | New York |
Columbia University Developmental Therapeutics Program: Striving for Excellence | Columbia University / Julia Glade Bender, MD | Phase I/II Infrastructure Grants | 2013 | New York |
The role of immunogenetics in natural killer cell targeting of neuroblastoma | Memorial Sloan-Kettering Cancer Center / Katharine Hsu | Innovation Grants | 2008 | New York |
Adaptation of acute lymphoblastic leukemia (ALL) to the post-transplant allogeneic environment. | University of Rochester / Craig Mullen | Innovation Grants | 2009 | New York |
Long Non-Coding RNAs as Novel Biomarkers and Therapeutic Targets in Pediatric Leukemia | New York University School of Medicine / Iannis Aifantis, PhD | Innovation Grants | 2017 | New York |
Ca2+ Release Activated Ca2+ (CRAC) Channels in Control of Leukemic Cell Metabolism and Leukemia Stem Cell Maintenance in T-ALL | New York University School of Medicine / Mate Maus, PhD | Young Investigator Grants | 2014 | New York |
Phosphopeptides as shared targets for donor derived T cell therapy of AML | Memorial Sloan-Kettering Cancer Center / Richard O'Reilly, MD | Innovation Grants | 2021 | New York |
Linking mitogenic sonic hedgehog signaling to the oncogene Yap 1 in neural stem/progenitor cells and medulloblastoma. | Memorial Sloan-Kettering Cancer Center / Anna Kenney, PhD | Innovation Grants | 2009 | New York |
Targeting Microenvironmental Support of Acute Lymphoblastic Leukemia | University of Rochester / Craig Mullen, MD/PhD | Innovation Grants | 2016 | New York |
Molecular Epidemiology to Detect Tumor Precursors in Children at Risk for Endemic Burkitt's Lymphoma | SUNY Upstate Medical University / Rosemary Rochford | Epidemiology Grants | 2008 | New York |
Hedgehog & IGF Signaling through IRSI in Brain Development and Medulloblastoma | Memorial Sloan-Kettering Cancer Center / Anna Marie Kenney, PhD | Young Investigator Grants | 2006 | New York |
BET Bromodomain Inhibition as Epigenetic Therapy in Pediatric Leukemia | Cold Spring Harbor Laboratory / Christopher Vakoc, MD, PhD | 'A' Award Grants | 2012 | New York |
Targeting CCAAT/enhancer binding proteins CEBPB and CEBPD in neuroblastoma | Columbia University / Darrell Yamashiro, MD/PhD | Innovation Grants | 2021 | New York |
Platform development for target identification in high risk pediatric leukemias | Columbia University / Adolfo A Ferrando, MD/PhD, Charles Mullighan, MD | Crazy 8 Pilots | 2019 | New York |
Epigenomics of High Risk Pediatric T Cell Leukemia | New York University School of Medicine / Iannis Aifantis, PhD | Reach Grants | 2013 | New York |
Elucidating the Role of N-Myc in a High-risk Pediatric T Cell Leukemia | New York University School of Medicine / Francesco Boccalatte, PhD | Young Investigator Grants | 2017 | New York |
Development of Novel Biomarkers for Immunotherapy in Neuroblastoma | Columbia Institute for Cancer Genetics / Shuobo Boboila, PhD | Young Investigator Grants | 2017 | New York |
Identifying Therapeutic Targets to Prevent Progression of Familial RUNX1 Disorder to AML Using Novel iPSC Models | Icahn School of Medicine at Mount Sinai / Eirini Papapetrou, MD/PhD | RARE Grant Program (Research Accelerating RUNX1 Exploration) | 2016 | New York |
IND-Enabling Studies for WNTinib, a Novel Selective Therapeutic for CTNNB1 Mutant Hepatoblastomas | Icahn School of Medicine at Mount Sinai / Ernesto Guccione, PhD & Josep Llovet, MD & Arvin Dar, PhD | Reach Grants | 2021 | New York |
Assessing Clonal Fitness and Mechanisms of Clonal Evolution in FPD-MN | Memorial Sloan-Kettering Cancer Center / Wenbin Xiao, MD/PhD | RUNX1 Early Career Investigator Grants | 2020 | New York |
The Impact of the Intestinal Microbiome on Sarcoma Metastasis | Albert Einstein College of Medicine / David Loeb, MD, PhD | Innovation Grants | 2023 | New York |
Resistance to anti-angiogenic therapy in pediatric solid tumors. | Feinstein Institute for Medical Research - North Shore / Samuel Soffer, MD | Young Investigator Grants | 2007 | New York |
Identification of TFAP4 (Transcription Factor AP-4/Activating Enhancer Binding Protein) as a Potential Master Regulator/Synthetic Lethal Gene of MYCN Amplified Neuroblastoma | Columbia University Medical Center / Darrell Yamashiro, MD, PhD | Innovation Grants | 2013 | New York |
Uncovering the Dysregulated RNA Binding Protein Network in Childhood Acute Myeloid Leukemia | Memorial Sloan-Kettering Cancer Center / Michael Kharas, PhD | 'A' Award Grants | 2016 | New York |
A leukemia organoid platform for dissection and targeting of tumor-niche interactions | Columbia Institute for Cancer Genetics / Adolfo Ferrando, MD/PhD | Innovation Grants | 2021 | New York |
Enhanced Drug Repurposing Screen in DSRCT Enabled by New In Vitro and In Vivo Models Based on CRISPR/Cas9 Genome Engineering | Memorial Sloan-Kettering Cancer Center / Marc Ladanyi, MD & Maria Jasin, PhD | Innovation Grants | 2015 | New York |
Development of an anti-KIR3DL1 Antibody to Promote Innate Immunity Against Neuroblastoma | Memorial Sloan-Kettering Cancer Center / Katherine Hsu, MD/PhD & Nai-Kong Cheung, MD/PhD | Innovation Grants | 2016 | New York |
Using Chemical Genetics to Define the Precise Role of RUNX1 in Transcription and Beyond | Albert Einstein College of Medicine / Kristy Stengel | RUNX1 Early Career Investigator Grants | 2022 | New York |
Developing drugs to treat NT5C2 mediated resistance in pediatric ALL | New York University School of Medicine / William Carroll, MD | Innovation Grants | 2019 | New York |
The p53-Mad2-Genomic Stability Pathway in the Development of Childhood Malignancies | Memorial Sloan-Kettering Cancer Center / Pascal Duijf | Young Investigator Grants | 2010 | New York |
Identification and Targeting of Microenvironmental Factors Controlling Pediatric Leukemia | New York University School of Medicine / Anastasia Tikhonova, PhD | Young Investigator Grants | 2017 | New York |
Characterizing the Developmental Context of Pediatric Leukemia | Icahn School of Medicine at Mount Sinai / Elvin Wagenblast, PhD | 'A' Award Grants | 2022 | New York |
Mechanisms and Targeted Inhibition of NT5C2 Mutations in Relapsed ALL | Columbia University / Adolfo A. Ferrando, M.D., Ph.D. | Innovation Grants | 2014 | New York |
Targeted Polymeric Parthenolide Carriers to Treat Childhood AML | University of Rochester / Danielle Benoit | Young Investigator Grants | 2010 | New York |
Modeling the Initiation and Progression of Down Syndrome Associated Leukemia Using CRISPR/Cas9 at Single Cell Resolution | Icahn School of Medicine at Mount Sinai / Elvin Wagenblast, PhD | Young Investigator Grants | 2020 | New York |
Targeting Neovascularization in Graft-Versus-Host Disease | Memorial Sloan-Kettering Cancer Center / Marcel van den Brink, MD/PhD | Innovation Grants | 2012 | New York |
Targeting Valine-Specific Amino Acid Dependency -in T-Cell Acute Lymphoblastic Leukemia | New York University School of Medicine / Palaniraja Thandapani, PhD | Young Investigator Grants | 2019 | New York |
Targeting Neovascularization in Graft-Versus-Host Disease | Memorial Sloan-Kettering Cancer Center / Marcel van den Brink | Innovation Grants | 2010 | New York |
Circumventing Pediatric Solid Tumor Microenvironment Resistance by Combinatorial CAR NK and Immunomodulating Therapy | New York Medical College / Mitchell Cairo, MD | Reach Grants | 2023 | New York |
Targeting Metabolic Vulnerabilities in ETP-ALL | Columbia University / Adolfo A. Ferrando, MD/PhD | Innovation Grants | 2017 | New York |
Developing Novel Transcription Factor PROTACs to Disrupt the HMGA1 Epigenome in Relapsed Leukemia | Icahn School of Medicine at Mount Sinai / Linda Resar, MD and Jian Jin, PhD | Innovation Grants | 2022 | New York |
Mechanisms of regulation of the PI#K/AKT pathway downstream of NOTCH1 in T-ALL. | Columbia University / Teresa Palomero, PhD | Young Investigator Grants | 2007 | New York |
Circulating Exosomes as Biomarkers of Medulloblastoma Progression, Metastasis, and Recurrence | Weill Cornell Medical College / David Lyden, MD/PhD & Parveen Raju, MD/PhD | Innovation Grants | 2016 | New York |
Developmental origins of leukemia in Down Syndrome | University of Rochester / James Palis, MD & Laurie Steiner, MD | Innovation Grants | 2022 | New York |
Function of the PR Domain of the MDSI-EVI1 in MLL Fusion Protein Leukemogenesis | University of Rochester / Archibald Perkins, MD, PhD | Springboard Grants | 2013 | New York |
Targeting a Novel Epigenetic Signature in Diffuse Intrinsic Pontine Gliomas | New York University School of Medicine / Danny Reinberg, PhD | Reach Grants | 2019 | New York |
Functional Dissection of Oncogenic Enhancers in T-ALL | Columbia University / Daniel Herranz, PhD | Young Investigator Grants | 2015 | New York |
The role of NOTCH1 in T-cell acute lymphoblastic leukemia. | Columbia University Medical Center / Adolfo Ferrando | Bridge Grants | 2012 | New York |
A New York Based Pediatric Oncology Developmental Therapeutics Program | Columbia University / Julia Glade Bender, MD | Phase I/II Infrastructure Grants | 2010 | New York |
Desmoplastic Small Round Cell Tumors: Investigation of its Pathogenesis and Development of Novel Therapies | Memorial Sloan-Kettering Cancer Center / Andrea Ventura, MD, PhD | Innovation Grants | 2023 | New York |
Targeting tumor associated macrophages in metastatic Ewing sarcoma (ES) | New York Medical College / Mitchell Cairo, MD | Innovation Grants | 2021 | New York |
Pre-Targeted Radioimmunotherapy for Desmoplastic Small Round Cell Tumors | Memorial Sloan-Kettering Cancer Center / Madelyn Espinosa-Cotton, PhD | Young Investigator Grants | 2023 | New York |
Preclinical Efficacy of Daratumumab in T Cell Acute Lymphoblastic Leukemia | New York University School of Medicine / Karen Bride, MD/PhD | Young Investigator Grants | 2017 | New York |
The role of primary cilia in rhabdomyosarcoma | New York University School of Medicine / Brian Dynlacht, PhD | Innovation Grants | 2011 | New York |
Rational Combination Therapy of AML | Memorial Sloan-Kettering Cancer Center / Alex Kentsis, MD, PhD | 'A' Award Grants | 2013 | New York |
Identification and Characterization of Pathways Dysregulated by MMSET E1099K Mutation in Relapsed Pediatric Acute Lymphoblastic Leukemia and Their Role in Drug Resistance | New York University School of Medicine / Joanna Pierro, DO | Young Investigator Grants | 2017 | New York |
Therapeutic Targeting of PGBD5-induced DNA Repair Dependency in Pediatric Solid Tumors | Memorial Sloan-Kettering Cancer Center / Alex Kentsis, MD/PhD | Reach Grants | 2017 | New York |
A New York Based Pediatric Oncology Developmental Therapeutics Program | Columbia University / Julia Glade Bender, MD | Phase I/II Infrastructure Grants | 2008 | New York |
Pre-clinical Evaluation of LSD1 Inhibitors for the Treatment of Pediatric Ewing sarcoma: Defining the Biomarkers of Sensitivity and Mechanisms of Resistance | Research Institute at Nationwide Children's Hospital / Kathleen Pishas, PhD | Young Investigator Grants | 2016 | Ohio |
Novel Therapeutic Target in Leukemia Stem Cells | Cincinnati Children's Hospital Medical Center / James Mulloy | Innovation Grants | 2010 | Ohio |
Using Splice Switching Oligonucleotides (SSOs) to target MDM2 for rhabdomyosarcoma therapy | Research Institute at Nationwide Children's Hospital / Dawn Chandler, PhD | Innovation Grants | 2019 | Ohio |
Targeting Pediatric Brain Tumors Using PTPmu Nanochains with Radiofrequency-Releasable Therapeutics | Case Western Reserve University / Susann Brady-Kalnay, PhD & Efstathios Karathanasis, PhD | Innovation Grants | 2017 | Ohio |
Generation of CMV-specific CD19 CAR T cells Using Cytokine Capture Followed by Lentiviral Transduction and Expansion | Research Institute at Nationwide Children's Hospital / Margaret Lamb, MD | Reach Grants | 2019 | Ohio |
Childhood Cancer Survivor Utilization and Barriers to Primary Care Providers | Research Institute at Nationwide Children's Hospital / Micah Skeens, PNP | Nurse Researcher Grants | 2012 | Ohio |
Targeting the Checkpoint Receptor TIGIT via CRISPR/Cas9 Genome Editing to Enhance NK Cell Anti-Tumor Activity | Research Institute at Nationwide Children's Hospital / Amanda Campbell, MD/PhD | Young Investigator Grants | 2023 | Ohio |
Targeting the Function of Ezrin in Rhabdomyosarcoma | The Cleveland Clinic Foundation / Neetu Gupta, PhD & Peter Anderson, MD | Innovation Grants | 2016 | Ohio |
Therapeutic Targeting of LARG-RhoA Signaling Axis in Childhood Leukemia | Cincinnati Children's Hospital Medical Center / Yi Zheng, PhD | Innovation Grants | 2013 | Ohio |
Redefining Osteosarcoma Metastases as Chronic Non-healing Lung Wounds: Implications for Developing Novel Therapies | Research Institute at Nationwide Children's Hospital / James Reinecke, MD/PhD | Young Investigator Grants | 2021 | Ohio |
Creating an Infrastructure for Collaborative Clinical Research and Publication of Consensus Guidelines for RUNX1 Familial Platelet Disorder | The Cleveland Clinic Foundation / Brittany Stewart, PhD | RUNX1 Early Career Investigator Grants | 2023 | Ohio |
Families of Children with Advanced Cancer: Quality of Life & Goals of Care | Research Institute at Nationwide Children's Hospital / Cindy Gerhardt, PhD | Psychosocial Family Impact Grant | 2017 | Ohio |
Improving Immune-Mediated Oncolytic Viral Therapy: Engineering Tumor Vaccine Elements into the Virus | Research Institute at Nationwide Children's Hospital / Kevin Cassady, MD & Christopher Walker, PhD | Innovation Grants | 2016 | Ohio |
Rac in p190-BCR-ABL0Induced Leukemia. | Cincinnati Children's Hospital Medical Center / Jose Cancelas, MD, PhD | Innovation Grants | 2007 | Ohio |
Novel STAT3 drug development for childhood osteosarcoma therapy using drug repositioning | Research Institute at Nationwide Children's Hospital / Jiayuh Lin, PhD | Innovation Grants | 2012 | Ohio |
Predictive Modeling of MDS Disease Progression From Inherited Bone Marrow Failure Syndrome Using Novel Branching Process and Next Generation Sequencing to Improve Patient-Specific Survival | Cleveland Clinic Foundation / Seth Corey, MD & Marek Kimmel, PhD | Innovation Grants | 2017 | Ohio |
The Phase I/II Trials Collaborative for Children, Adolescents, and Young Adults at UH Rainbow Babies & Children's Hospital and the Case Comprehensive Cancer Center | Case Western Reserve University / Letterio, John MD & Matloub, Yousif MD | Phase I/II Infrastructure Grants | 2013 | Ohio |
Virotherapy on Primary Neuroblastoma Cells | Cincinnati Children's Hospital Medical Center / Pin-Yi Wang | Young Investigator Grants | 2010 | Ohio |
Unraveling the Function of PAX3-FOXO1’s Activation Domain in Rhabdomyosarcoma | Case Western Reserve University / Berkley Gryder, PhD | 'A' Award Grants | 2023 | Ohio |
Research Institute at Nationwide Children's Hospital / Mary Beth Ross, MD/PhD | Young Investigator Grants | 2006 | Ohio | |
WWOX as a Signal Mediator in Pediatric Osteosarcoma | The Ohio State University / Rami Aqeilan | 'A' Award Grants | 2009 | Ohio |
Bad Influence: EWS/FLI Alters LSD1 and NuRD Interactions to Enforce Oncogenic Function in Ewing’s | Research Institute at Nationwide Children's Hospital / Emily Theisen, PhD | Young Investigator Grants | 2016 | Ohio |
Development of MicroRNA-Nanoparticles to Treat Childhood Acute Leukemia Carrying MLL Rearrangements | University of Cincinnati College of Medicine / Jianjun Chen, PhD | Innovation Grants | 2013 | Ohio |
Developing Immune-modulatory Strategies Against Primary and Metastatic Tumors in the Central Nervous System | Case Western Reserve University / Alex Huang, MD, PhD | Innovation Grants | 2012 | Ohio |
Cure Osteosarcoma Lung Metastasis by Disrupting Tumor VCAM-1 Signaling with Macrophages | Case Western Reserve University / Alex Huang, MD, PhD | Innovation Grants | 2015 | Ohio |
Generation of a novel oncolytic virus for treatment of pediatric brain tumors. | The Ohio State University / Balveen Kaur, PhD | Young Investigator Grants | 2007 | Ohio |
Mechanisms of PAX3-FOXO1 and HES3 Cooperation in Rhabdomyosarcoma | Nationwide Children’s Hospital / Genevieve Kendall, PhD | 'A' Award Grants | 2018 | Ohio |
Untangling the Matrix in Medulloblastoma | St. Christopher's Hospital for Children / Duncan Stearns, MD | Young Investigator Grants | 2008 | Ohio |
Epigenetic manipulation of leukemia. | Cincinnati Children's Hospital Medical Center / H. Leighton Grimes | Innovation Grants | 2009 | Ohio |
Nationwide Children's Hospital Phase I/II Infrastructure | Research Institute at Nationwide Children's Hospital / Sarah O'Brien, MD and Timothy Cripe, MD, PhD | Phase I/II Infrastructure Grants | 2013 | Ohio |
PainSquad+: A Smartphone App to Support Real-Time Pain Management for Adolescents with Cancer | Hospital for Sick Children / Jennifer Stinson, RN, PhD | Nurse Researcher Grants | 2013 | Ontario |
Therapeutic Targets and Molecular Mechanisms in Childhood Brainstem Tumors | University Health Network - Toronto Western Research Institute / Jerome Fortin, PhD | Young Investigator Grants | 2019 | Ontario |
Deciphering the Mechanisms of Medulloblastoma Treatment Resistance using Integrative Genomics | Hospital for Sick Children / Vijay Ramaswamy, MD | Young Investigator Grants | 2014 | Ontario |
Dissecting Pediatric Brain Tumour Progression Using Single-nuclei Sequencing | University Health Network / Trevor Pugh, PhD | Single-cell Pediatric Cancer Atlas Grant | 2019 | Ontario |
Genomic Discovery of Wilms Tumor | Samuel Lunenfeld Research Institute of Mount Sinai Hospital / Rayjean Hung, PhD | Epidemiology Grants | 2014 | Ontario |
To test the feasibility, acceptability and effectiveness of a sleep hygiene and relaxation intervention to improve sleep and fatigue for children receiving maintenance therapy for acute lymphoblastic leukemia | Hospital for Sick Children / Sue Zupanec | Nurse Researcher Grants | 2010 | Ontario |
Pediatric Precision Oncology: Parent and Adolescent Experiences | Hospital for Sick Children / Anita Villani, MD | Psychosocial Launch Grant | 2017 | Ontario |
Establishing surrogate markers of angiogenesis in pediatric oncology phase I and II clinical trials: A Children’s Oncology Group study | Hospital for Sick Children / Sylvain Baruchel, MD | Innovation Grants | 2007 | Ontario |
The Effect of Locus of Care Upon Adolescent and Young Adults Cancer Outcomes: An IMPACT Cohort Study | Hospital for Sick Children / Sumit Gupta, MD, PhD | Young Investigator Grants | 2015 | Ontario |
SickKids MIBG and Phase I Leukemia Programs | Hospital for Sick Children / James Whitlock, MD | Phase I/II Infrastructure Grants | 2011 | Ontario |
Role of Inflammatory Microenvironment in Clonal evolution and Progression from FPD to AML | Oregon Health & Science University / Anupriya Agarwal, PhD | RARE Grant Program (Research Accelerating RUNX1 Exploration) | 2017 | Oregon |
Nuclear Receptor Tyrosine Kinases Mediating Chromatin Remodeling & Checkpoint Adaption | Children’s Cancer Therapy Development Institute / Charles Keller, MD | Innovation Grants | 2018 | Oregon |
Therapeutics In Ovo | Oregon Health & Science University / Charles Keller | Innovation Grants | 2008 | Oregon |
Pediatric Oncology Investigational Therapeutics. | Doernbecher Children’s Hospital Foundation / Linda Stork, MD | Phase I/II Infrastructure Grants | 2007 | Oregon |
Moving EphB4 Therapeutics to Pediatric Phase I/II Trials | Oregon Health & Science University / Charles Keller, MD | Reach Grants | 2013 | Oregon |
CAMKV as a Target for Immunotherapy in MYCN-Amplified Neuroblastoma | Children’s Hospital of Philadelphia / Robyn Sussman, PhD | Young Investigator Grants | 2015 | Pennsylvania |
Next-Generation Personalized Neuroblastoma Therapy (Nepenthe) | Children’s Hospital of Philadelphia / Yael Mosse, MD & John Maris, MD | Bio-Therapeutic Impact Award | 2015 | Pennsylvania |
Kidney Disease after CD19-Targeted Chimeric Antigen Receptor T Cell Therapy for Pediatric Acute Lymphoblastic Leukemia | Children’s Hospital of Philadelphia / Regina Myers, MD | Young Investigator Grants | 2019 | Pennsylvania |
Drugging MYCN | Children’s Hospital of Philadelphia / Yael Mossé, MD | Crazy 8 Awards | 2020 | Pennsylvania |
Defining the Cell Surface Landscape of Diagnostic and Relapsed Neuroblastoma: Immunotherapeutic Target Identification | Children’s Hospital of Philadelphia / Sharon Diskin, PhD | Innovation Grants | 2017 | Pennsylvania |
Generation of CHD5 Antibodies and Know-out Mouse Model | Children’s Hospital of Philadelphia / Garrett Brodeur | Innovation Grants | 2008 | Pennsylvania |
Augmenting Chimeric Antigen Receptor T Cell Induced Epitope Spreading for Pediatric Solid Tumors | Children’s Hospital of Philadelphia / Michael Leibowitz, MD/PhD | Young Investigator Grants | 2018 | Pennsylvania |
Impact of STAG2 loss on DNA Damage and Immunobiology in Ewing sarcoma | University of Pittsburgh / Kelly Bailey, MD, PhD | Innovation Grants | 2022 | Pennsylvania |
Targeting Metabolism as a Therapeutic Approach for High-Risk MYCN-Driven Neuroblastoma | University of Pennsylvania / Nicole Anderson, PhD | Young Investigator Grants | 2016 | Pennsylvania |
Cooperating Signaling Networks Regulate Cell Survival of Pediatric Ph-like ALL | University of Pennsylvania / Christian Hurtz, PhD | Young Investigator Grants | 2018 | Pennsylvania |
Development of Targeted Therapies in High Risk Childhood Acute Lymphoblastic Leukemia | Children’s Hospital of Philadelphia / Sarah Tasian | Young Investigator Grants | 2012 | Pennsylvania |
Loss of ER-mitochondria contacts drives therapy resistance in neuroblastoma | Children’s Hospital of Philadelphia / Michael Hogarty, MD | Innovation Grants | 2021 | Pennsylvania |
Children's Hospital of Pittsburgh of UPMC Phase 1-2 Infrastructure Support Grant | University of Pittsburgh / A. Kim Ritchey | Phase I/II Infrastructure Grants | 2011 | Pennsylvania |
Mechanisms Regulating Medulloblastoma Progression | University of Pennsylvania / Nadia Dahmane, PhD | Innovation Grants | 2013 | Pennsylvania |
Radiation and the Tumor Microenvironment in an Immunocompetent Model of Ewing Sarcoma | Children’s Hospital of Pittsburgh Foundation / Jessica Daley, MD | Young Investigator Grants | 2023 | Pennsylvania |
Epigenomic Mechanisms of Neuroblastoma Tumorigenesis | Children’s Hospital of Philadelphia / Jo Lynne Harenza, PhD | Young Investigator Grants | 2017 | Pennsylvania |
Integration of Targeted New Agents with Chemotherapy | Children’s Hospital of Philadelphia / Robin Norris, MD | Young Investigator Grants | 2008 | Pennsylvania |
Alex's Lemonade Stand Foundation Center of Excellence in Childhood Cancer Drug Development and Clinical Pharmacology at The Children's Hospital of Philadelphia | Children’s Hospital of Philadelphia / Frank Balis, MD - Scholar: Emily Blauel, MD | Center of Excellence Grants | 2013 | Pennsylvania |
Preclinical Development of Targeted Therapy for Neuroblastoma with ALK and CDK4/6 Dual Pathway Inhibition | Children’s Hospital of Philadelphia / Yael Mossé, MD | Reach Grants | 2013 | Pennsylvania |
The Role of the Innate Immune System in Immune Dysregulation following CART | Children’s Hospital of Philadelphia / Caroline Diorio, MD | 'A' Award Grants | 2023 | Pennsylvania |
Impact of Pediatric Germline Testing in a Pediatric Cancer Predisposition Clinic | Children’s Hospital of Philadelphia / Lisa Schwartz, PhD | Psychosocial Family Impact Grant | 2018 | Pennsylvania |
Evaluation of the Prevalence of Diaper Dermatitis in Pediatric Leukemia. | Children’s Hospital of Philadelphia / Beth Storey | Nurse Researcher Grants | 2008 | Pennsylvania |
In-UTR mutations in neuroblastoma: Functional consequences and therapeutic implications | Children’s Hospital of Philadelphia / Andrei Thomas-Tikhonenko, PhD | Innovation Grants | 2012 | Pennsylvania |
Hematopoietic Stem And Progenitor Cells Sustain Inflammation And Promote Relapse In The AML Niche | Children’s Hospital of Philadelphia / Ding-Wen (Roger) Chen, PhD | Young Investigator Grants | 2021 | Pennsylvania |
GPC2 CAR T Cell Targeted Delivery of BiKEs in High-Risk Neuroblastoma | Children’s Hospital of Philadelphia / Guillem Pascual-Pasto, PhD | Young Investigator Grants | 2020 | Pennsylvania |
In-UTR Mutations in Neuroblastoma: Functional Consequences and Therapeutic Implications | Children’s Hospital of Philadelphia / Andrei Thomas-Tikhonenko | Innovation Grants | 2010 | Pennsylvania |
Astatine-211 Meta-Astatobenzylguanidine ([211At]MABG) Targeted Radiotherapy for Disseminated Neuroblastoma | Children’s Hospital of Philadelphia / John Maris, MD | Reach Grants | 2016 | Pennsylvania |
Children's Hospital of Pittsburgh of UPMC Phase 1-2 Infrastructure Support Grant | University of Pittsburgh / Jean Tersak, MD | Phase I/II Infrastructure Grants | 2013 | Pennsylvania |
E2A translocations in pediatric leukemia: developing new therapeutic targets | Children’s Hospital of Philadelphia / Bruce Fischer, MD | Young Investigator Grants | 2007 | Pennsylvania |
Cancer Risk and Incidence in Beckwith-Wiedemann Syndrome | Children’s Hospital of Philadelphia / Jennifer Kalish, MD/PhD | Epidemiology Grants | 2019 | Pennsylvania |
Multivalent Nanomedicine to Treat High-Risk Pediatric Solid Tumors | Children’s Hospital of Philadelphia / Garrett Brodeur, MD | Reach Grants | 2019 | Pennsylvania |
Norepinephrine Transporter-Targeted Pharmacotherapy of Aggressive Neuroblastoma | Children’s Hospital of Philadelphia / Michael Chorny, PhD | Innovation Grants | 2019 | Pennsylvania |
Novel targeting approach for pediatric B-cell malignancies | Thomas Jefferson University / Christine Eischen, PhD | Innovation Grants | 2021 | Pennsylvania |
Sepsis as innate immune stimulus: severe sepsis exposures and protection against relapse in children with acute leukemias | Children’s Hospital of Philadelphia / Alix Seif, MD | Epidemiology Grants | 2016 | Pennsylvania |
Targeting MYCN | Children’s Hospital of Philadelphia / Yael Mossé, MD & Julie Park, MD | Crazy 8 Pilots | 2019 | Pennsylvania |
The Tumor Suppressive Role of LNK (SH2B3) in Acute Lymphoblastic Leukemia | Children’s Hospital of Philadelphia / Wei Tong, PhD | Innovation Grants | 2014 | Pennsylvania |
Micro-environmental Regulators of Ewing sarcoma Metastasis | University of Pittsburgh / Kelly Bailey, MD/PhD | Young Investigator Grants | 2016 | Pennsylvania |
APOBEC3 in Pediatric Leukemia: a Biomarker for Sensitivity to PARP Inhibition? | Children’s Hospital of Philadelphia / Abby Green, MD | Young Investigator Grants | 2014 | Pennsylvania |
BH3 profiling to define therapy resistance classes in neuroblastoma. | Children’s Hospital of Philadelphia / Michael Hogarty | Innovation Grants | 2009 | Pennsylvania |
Trib2 in the Pathogenesis of T-ALL | University of Pennsylvania / Warren Pear, M.D., Ph.D., | Innovation Grants | 2014 | Pennsylvania |
Dissecting the Mechanism of Overgrowth and Tumorigenesis in Beckwith-Wiedemann Syndrome | University of Pennsylvania / Jennifer Kalish, MD, PhD | Young Investigator Grants | 2013 | Pennsylvania |
BH3 Profiling to define therapy resistance classes in neuroblastoma | Children’s Hospital of Philadelphia / Michael Hogarty, MD | Innovation Grants | 2011 | Pennsylvania |
Beyond Febrile Neutropenia: Risks Associated with Antibiotic Choice in Children with Leukemia that Undergo Transplant | Children’s Hospital of Philadelphia / Caitlin Elgarten, MD | Young Investigator Grants | 2018 | Pennsylvania |
Therapeutic targeting of clonal hematopoiesis in RUNX1 mutant FPDMM | University of Pennsylvania / Robert Bowman, Ph.D. | RARE Grant Program (Research Accelerating RUNX1 Exploration) | 2024 | Pennsylvania |
Targeting Protein Translation to Antagonize MYC-driven Neuroblastoma | Children’s Hospital of Philadelphia / Andrea Flynn, MD | Young Investigator Grants | 2017 | Pennsylvania |
Developmental Therapeutics and Translational Research Program | Children’s Hospital of Philadelphia / John Maris | Phase I/II Infrastructure Grants | 2005 | Pennsylvania |
Drug Screen for FPD/AML Therapeutics | Children’s Hospital of Philadelphia / Mortimer Poncz, MD | RARE Grant Program (Research Accelerating RUNX1 Exploration) | 2017 | Pennsylvania |
Nanoparticle Delivery of Therapeutic Agents in Neuroblastomas | Children’s Hospital of Philadelphia / Garrett M. Brodeur, MD | Innovation Grants | 2013 | Pennsylvania |
Elucidating the Role of SETD2 in Pediatric High Grade Glioma Formation | Children’s Hospital of Philadelphia / Thomas De Raedt, PhD | 'A' Award Grants | 2019 | Pennsylvania |
Mothers and Fathers Perspectives: Family Management of Young Adult Survivors of Childhood Brain Tumors | University of Pennsylvania / Janet Deatrick | Nurse Researcher Grants | 2010 | Pennsylvania |
Activating Metabolic Pathways to Increase the Persistence of Leukemia Targeting T Cells | Children’s Hospital of Pittsburgh / Erica Braverman, MD | Young Investigator Grants | 2021 | Pennsylvania |
Identify Novel Druggable Targets to Treat Philadelphia chromosome-like B-Acute Lymphoblastic Leukemia | Children’s Hospital of Philadelphia / Wei Tong, PhD | Innovation Grants | 2019 | Pennsylvania |
A Comparison of Parent and Clinician Reported Toxicities in Standard Radiation Versus Proton Beam Radiation in Children with Posterior Fossa Tumors. | Children’s Hospital of Philadelphia / Rosanna Pollack, RN & Cynthia Schmus, RN | Nurse Researcher Grants | 2007 | Pennsylvania |
Clinical Epidemiology Studies in Children's Oncology Group Clinical Trials | Children’s Hospital of Philadelphia / Richard Aplenc, MD, PhD, MSCE | Epidemiology Grants | 2013 | Pennsylvania |
Children's Hospital of Pittsburgh Phase 1-2 Infrastructure Support Grant | University of Pittsburgh / A. Kim Ritchey, MD | Phase I/II Infrastructure Grants | 2008 | Pennsylvania |
Exploiting glypican diversity in neuroblastoma plasticity with bicistronic CAR T cell targeting | Children’s Hospital of Philadelphia / Kristopher Bosse, MD | 'A' Award Grants | 2022 | Pennsylvania |
Trk-Targeted Therapy of Human Neuroblastomas | Children’s Hospital of Philadelphia / Garrett Brodeur, M.D. | Bridge Grants | 2014 | Pennsylvania |
Modeling Genetic Modifiers of Down Syndrome Leukemogenesis | Children’s Hospital of Philadelphia / Stella T. Chou, MD | Springboard Grants | 2013 | Pennsylvania |
Alternative Splicing in the Pathogenesis of Acute Lymphoblastic Leukemia | Children’s Hospital of Philadelphia / Andrei Thomas-Tikhonenko, PhD | Innovation Grants | 2017 | Pennsylvania |
DFMO Synergy with Chemo-immunotherapy to Eradicate MYC-Driven Neuroblastoma | Children’s Hospital of Philadelphia / Michael Hogarty, MD | Reach Grants | 2016 | Pennsylvania |
Hospital Volume and Induction Mortality in Children, Adolescents, and Young Adults with Acute Leukemia | Children’s Hospital of Philadelphia / Jennifer Wilkes, MD | Young Investigator Grants | 2014 | Pennsylvania |
Vaccine-boosted CAR T cell therapy for high risk neuroblastoma | Children’s Hospital of Philadelphia / Timothy Spear, MD/PhD | Young Investigator Grants | 2024 | Pennsylvania |
Bcl2-Family Inhibitors in Neuroblastoma: Mechanism of Action, Therapy Resistance, and Development of Biomarkers | Children’s Hospital of Philadelphia / Claudia Zapata, MD | Young Investigator Grants | 2019 | Pennsylvania |
Variation in Care and Outcomes in Pediatric Acute Leukemia | Children’s Hospital of Philadelphia / Amanda DiNofia, MD | Young Investigator Grants | 2016 | Pennsylvania |
Biology-based clinical trials for children with cancer. | Children’s Hospital of Philadelphia / Rochelle Bagatell | Phase I/II Infrastructure Grants | 2009 | Pennsylvania |
Modeling Juvenile Myelomonocytic Leukemia with Patient-Derived Induced Pluripotent Stem Cells | Children’s Hospital of Philadelphia / Mitchell Weiss, M.D., Ph.D. | Innovation Grants | 2014 | Pennsylvania |
Defining the Mechanism by which LIN28B acts as an Oncogene in Neuroblastoma | Children’s Hospital of Philadelphia / Robert Schnepp, MD, PhD | Young Investigator Grants | 2013 | Pennsylvania |
GPC2 as an Oncogene and Immunotherapeutic Target in High-risk Neuroblastoma | Children’s Hospital of Philadelphia / Kristopher Bosse, MD | Young Investigator Grants | 2016 | Pennsylvania |
Single-cell Profiling of Early T-cell Precursor Acute Lymphoblastic Leukemia | Children’s Hospital of Philadelphia / David Teachey, MD and Kai Tan, PhD | Single-cell Pediatric Cancer Atlas Grant | 2019 | Pennsylvania |
CD19 Delta Ex2 Isoform as a Target for Alternative Therapies in Relapsed Pediatric B-ALL | Children’s Hospital of Philadelphia / Asen Bagashev, PhD | Young Investigator Grants | 2016 | Pennsylvania |
Pharmacogenomics of childhood AML susceptibility and treatment response. | Children’s Hospital of Philadelphia / Richard Aplenc | Innovation Grants | 2009 | Pennsylvania |
Role of Myosin VI in Pediatric Glioma Proliferation and Invasion | University of Pennsylvania / Monalisa Mukherjea | Young Investigator Grants | 2012 | Pennsylvania |
Assessing the Relationship Between Physical Activity, Fatigue and Health Related Quality of Life in Children Receiving Cancer Treatment | Children’s Hospital of Philadelphia / Pattianne Belfield, PNP, CRNP | Nurse Researcher Grants | 2012 | Pennsylvania |
Epigenetic Characterization of the Neuroblastoma Driver Genes ARID1A and ARID1B | Children’s Hospital of Philadelphia / Michael Hogarty, MD | Innovation Grants | 2013 | Pennsylvania |
Pedi-PRESTO: Pediatric Patient-Reported Symptom Tracking in Oncology | Children’s Hospital of Philadelphia / Allison Barz Leahy, MD | Young Investigator Grants | 2018 | Pennsylvania |
Neighborhood Factors, Acute Kidney Injury and Disparities in Pediatric Acute Myeloid Leukemia | Children’s Hospital of Philadelphia / Richard Aplenc, MD/PhD | Epidemiology Grants | 2018 | Pennsylvania |
Targeted Combination Therapy to Sensitize High-Risk Acute Lymphoblastic Leukemia to Methotrexate via Restoration of Ikaros Tumor Suppression | The Pennsylvania State University / Sinisa Dovat, MD/PhD & Chunhua Song, MD/PhD | Innovation Grants | 2016 | Pennsylvania |
Anthracycline-Induced Cardiac Toxicity in Pediatric Acute Myeloid Leukemia | University of Pennsylvania / Kelly Getz, PhD | Young Investigator Grants | 2017 | Pennsylvania |
Arginine Depletion with DFMO in High-Risk Neuroblastoma | Children’s Hospital of Philadelphia / Christina Turn, MD | Young Investigator Grants | 2023 | Pennsylvania |
Characterization and Targeting of Novel Activating BRAF Mutations in Pediatric Brain Tumors | Children’s Hospital of Philadelphia / Angela Waanders, MD, MPH | Young Investigator Grants | 2010 | Pennsylvania |
Social Determinants of Health, Hospital-level Resources, and Risk of Septic Shock in Pediatric Leukemia | Children’s Hospital of Philadelphia / Jenny Ruiz, MD | Young Investigator Grants | 2021 | Pennsylvania |
Anti-Angiogenic Effects of BAI Proteins in Neuroblastoma | Children’s Hospital of Philadelphia / Naomi Balamuth, MD | Young Investigator Grants | 2006 | Pennsylvania |
Novel Genomic Drivers in Pediatric Polyposis Syndromes | Children’s Hospital of Philadelphia / Suzanne MacFarland, MD | Young Investigator Grants | 2019 | Pennsylvania |
Molecular Annotation for Treatment of Childhood Cancers Trial: Neuroblastoma (MATCH-NB) | Children’s Hospital of Philadelphia / Yael Mosse, M.D. | Bio-Therapeutic Impact Award | 2015 | Pennsylvania |
Novel Synergistic Targets for Combination Therapy in Philadelphia Chromosome-like Acute Lymphoblastic Leukemia | Children’s Hospital of Philadelphia / Yang Ding, MD | Young Investigator Grants | 2020 | Pennsylvania |
Development of Immunostimulatory DNA as a Novel Therapy in Pediatric Acute Lymphoblastic Leukemia | Children’s Hospital of Philadelphia / Alix Seif, MD, MPH | Young Investigator Grants | 2008 | Pennsylvania |
Targeting Kinase Inhibitor Induced DNA-Damage Response in Ph-Like ALL | Temple University / Christian Hurtz, PhD | 'A' Award Grants | 2022 | Pennsylvania |
Tumor cell hybridoma vaccine for recurrent neuroblastoma and Ewing sarcoma | The Pennsylvania State University / Ken Lucas, MD | Innovation Grants | 2006 | Pennsylvania |
Identification of Synthetically Immunogenic Compounds to Synergize with Immunotherapy in Neuroblastoma | Children’s Hospital of Philadelphia / Adam Wolpaw, MD/PhD | Young Investigator Grants | 2019 | Pennsylvania |
Factors Influencing the Decision to Provide General Anesthesia or Moderate Sedation for Treatment Related Procedures in Children with Cancer | Children’s Hospital of Philadelphia / Elizabeth Ely, PhD, RN | Nurse Researcher Grants | 2007 | Pennsylvania |
The role of overexpressed microRNA’s in the pediatric cancer rhabdomyosarcoma | University of Pennsylvania / Frederic Barr, MD, PhD | Innovation Grants | 2007 | Pennsylvania |
DICER1, MicroRNAs and Pediatric Cancer: An Emerging Story | Research Institute of the McGill University Health Centre / William Foulkes, MD, PhD | Innovation Grants | 2013 | Quebec |
Cancer Susceptibility and Signaling Pathways in Low-Grade Brain Tumors | Jewish General Hospital / Bárbara Rivera, PhD | Young Investigator Grants | 2017 | Quebec |
Identifying targeted treatments for DICER1-associated sarcomas | Research Institute of the McGill University Health Centre / William Foulkes, MD/PhD & Sidong Huang, PhD | Innovation Grants | 2019 | Quebec |
Uncovering the signaling mechanisms allowing medulloblastoma progenitor cells to orchestrate tumor relapse | Medical University of South Carolina / Jezabel Rodriguez Blanco, PhD | 'A' Award Grants | 2023 | South Carolina |
CD36-Sphingosine 1-Phosphate Axis in Osteosarcoma Progression | Medical University of South Carolina / Meenal Mehrotra, MD/PhD | Innovation Grants | 2019 | South Carolina |
Evaluation of the Literacy Demand and Racial/Ethnic Influences for Self-Reported Symptomatic Adverse Events during Childhood Cancer Therapy | Palmetto Health / Janice Withycombe, PhD | Nurse Researcher Grants | 2013 | South Carolina |
Novel Targeted Therapies for Rhabdomyosarcoma | St. Jude Children’s Research Hospital / Michael Dyer, PhD | Innovation Grants | 2013 | Tennessee |
Capitalizing on functional genomics with targeted protein degradation in neuroblastoma | St. Jude Children’s Research Hospital / Ian Delahunty, PhD | Young Investigator Grants | 2024 | Tennessee |
Investigation of Pediatric Rhabdomyosarcoma Recurrence through Single-Cell Sequencing | St. Jude Children’s Research Hospital / Anand Patel, MD/PhD | Young Investigator Grants | 2019 | Tennessee |
Modifying CAR T cell epigenetic programs to improve therapy against aggressive pediatric brain tumors | St. Jude Children’s Research Hospital / Meghan Ward, PhD | Young Investigator Grants | 2024 | Tennessee |
Describing the Biological Impacts of Gain-of-function SAMD9 Mutations | Vanderbilt University Medical Center / Jason Schwartz, MD/PhD | Young Investigator Grants | 2018 | Tennessee |
Functional Characterization of RELA Fusion Ependymoma as a Basis for Therapeutic Targeting | St. Jude Children’s Research Hospital / Stephen Mack, PhD | 'A' Award Grants | 2018 | Tennessee |
Interrogation of Neuroblastoma Dependencies and RNAs on the Core-Regulatory Circuitry for Therapeutic Inhibition | St. Jude Children’s Research Hospital / Adam Durbin, PhD | Young Investigator Grants | 2018 | Tennessee |
MYC as a Driver and Anti-Cancer Target in Malignant Rhabdoid Tumors | Vanderbilt University Medical Center / William Tansey, PhD | Innovation Grants | 2016 | Tennessee |
Single-cell Profiling of Childhood Acute Lymphoblastic Leukemia | St. Jude Children’s Research Hospital / Charles Mullighan, MD and Jeffrey Klco, MD/PhD | Single-cell Pediatric Cancer Atlas Grant | 2019 | Tennessee |
Genetic Profiling and Experimental Modeling of High-risk Acute Lymphoblastic Leukemia | St. Jude Children’s Research Hospital / Kathryn Roberts, PhD | Young Investigator Grants | 2013 | Tennessee |
Profiling the Transcriptional Heterogeneity of Diverse Pediatric Solid Tumors | St. Jude Children’s Research Hospital / Michael Dyer, PhD and Xiang Chen, PhD | Single-cell Pediatric Cancer Atlas Grant | 2019 | Tennessee |
Pediatric Oncology Translational Research Program | Vanderbilt University Medical Center / James Whitlock, M.D. | Phase I/II Infrastructure Grants | 2009 | Tennessee |
Small Molecule Degraders for Targeting Transcription Factor Drivers of Childhood Cancers | St. Jude Children’s Research Hospital / Charles G. Mullighan, MBBS(Hons), MSc, MD, FRACP, FRCPA | Crazy 8 Awards | 2020 | Tennessee |
Testing a Hospital Sleep Hygiene Intervention | St. Jude Children’s Research Hospital / Belinda Mandrell, PhD, RN | Nurse Researcher Grants | 2007 | Tennessee |
NUDT15 Polymorphisms and Individualization of Thiopurine Therapy in Children with Acute Lymphoblastic Leukemia | St. Jude Children’s Research Hospital / Takaya Moriyama, MD/PhD | Young Investigator Grants | 2018 | Tennessee |
Targeting polycomb-mediated epigenetic silencing in T cell acute lymphoblastic leukemia | Vanderbilt University Medical Center / Emmanuel Volanakis | Young Investigator Grants | 2011 | Tennessee |
Effect of SLCO Polymorphisms on High-Dose Methotrexate Clearance in Pediatric Oncology Patients | Vanderbilt University Medical Center / Rachael Schulte, MD | Young Investigator Grants | 2018 | Tennessee |
Inflammatory Signaling in the Tumor Microenvironment | St. Jude Children’s Research Hospital / Peter J. Murray, PhD | Springboard Grants | 2013 | Tennessee |
Neurocognitive Outcomes in Survivors of Childhood Leukemia with Down Syndrome | St. Jude Children’s Research Hospital / Lisa Jacola, PhD | Psychosocial Grants | 2016 | Tennessee |
Pediatric Oncology Translational Research Program. | Vanderbilt University Medical Center / James Whitlock, MD | Phase I/II Infrastructure Grants | 2006 | Tennessee |
Pediatric Osteosarcoma: Identifying the elusive molecular signature and its relationship to this disease | St. Jude Children’s Research Hospital / Linda Hendershot, PhD | Innovation Grants | 2019 | Tennessee |
Isoform-specific TNC-redirected T cell Therapy for DIPG | St. Jude Children’s Research Hospital / Stephen Gottschalk, MD and Giedre Krenciute, PhD | Innovation Grants | 2022 | Tennessee |
MTG-16 Regulation by Phosphorylation | Vanderbilt University Medical Center / Michael Engel, MD, PhD | Young Investigator Grants | 2006 | Tennessee |
CD47-blocking Oncolytic Vaccinia Viruses as Biotherapeutics for Pediatric Solid Tumors | St. Jude Children’s Research Hospital / Stephen Gottschalk, MD & Nino Rainusso, MD | Innovation Grants | 2016 | Tennessee |
Mutagenesis and disease progression in RUNX1 mutant blood stem cells is caused by inflammation-induced hyperactive signaling and supraphysiological mitochondrial ROS | St. Jude Children’s Research Hospital / Dirk Loeffler, PhD | RUNX1 Early Career Investigator Grants | 2023 | Tennessee |
ECM-targeted CAR T-cell therapy for high-grade glioma | St. Jude Children’s Research Hospital / Jessica Wagner, PhD | Young Investigator Grants | 2019 | Tennessee |
Improving CAR T-Cell Therapy for Pediatric Osteosarcoma by Manipulating Arginine Metabolism | St. Jude Children’s Research Hospital / Shannon Lange, PhD | Young Investigator Grants | 2019 | Tennessee |
Investigating Epigenetic Mechanisms of Response to Allogenic CAR T Cell Therapy | St. Jude Children’s Research Hospital / Caitlin Zebley, MD/PhD | Young Investigator Grants | 2021 | Tennessee |
Enhancing Coping and Communication in Children with Cancer and Their Parents: A Novel Internet-Based Intervention | Vanderbilt University Medical Center / Bruce Compas, PhD | Psychosocial Grants | 2016 | Tennessee |
Targeting microenvironment-induced TGFB signaling to overcome drug resistance in acute lymphoblastic leukemia | St. Jude Children’s Research Hospital / Charles Mullighan, MD | Innovation Grants | 2019 | Tennessee |
Targeting wnt in synovial sarcoma models. | Vanderbilt University Medical Center / Josiane Eid | Innovation Grants | 2009 | Tennessee |
The role of PDE4B in Racial Disparities in Outcome of Childhood Acute Lymphoblastic Leukemia | St. Jude Children’s Research Hospital / Jun Yang | Young Investigator Grants | 2010 | Tennessee |
Single Nuclear RNA-seq and Spatial Transcriptomic Analysis of Anaplastic and Favorable Histology Wilms Tumor | St. Jude Children’s Research Hospital / Andrew Murphy, MD and Xiang Chen, PhD | Single-cell Pediatric Cancer Atlas Grant | 2019 | Tennessee |
Platform development for target identification in high risk pediatric leukemias | St. Jude Children’s Research Hospital / Adolfo A Ferrando, MD/PhD, Charles Mullighan, MD | Crazy 8 Pilots | 2019 | Tennessee |
Ex Vivo Modeling of Medulloblastoma using Human iPSC-Derived Cerebellar Organoids | St. Jude Children’s Research Hospital / Stephanie Wu, PhD | Young Investigator Grants | 2023 | Tennessee |
A novel mouse model of rhabdomyosarcoma | Vanderbilt University Medical Center / Chin Chiang, PhD | Innovation Grants | 2012 | Tennessee |
Inside-Out Immunotherapy: Combating Neuroblastoma via Nanoparticle-Directed Reprogramming of the Tumor Microenvironment | Vanderbilt University Medical Center / John Wilson, PhD | 'A' Award Grants | 2015 | Tennessee |
Mechanisms of LYL1-associated T-ALL development | Baylor College of Medicine / Margaret Goodell, PhD | Innovation Grants | 2012 | Texas |
Optimizing Engager T-cells for CD19+ Malignancies | Baylor College of Medicine / Mireya Paulina Velasquez, MD | Young Investigator Grants | 2014 | Texas |
Engager T cells for the Adoptive Immunotherapy of Pediatric Malignancies | Baylor College of Medicine / Stephen Gottschalk, MD | Innovation Grants | 2013 | Texas |
MYCN-induced molecular clock disruption and metabolic rewiring drive neuroblastoma | Baylor College of Medicine / Lingzhi Li, PhD | Young Investigator Grants | 2024 | Texas |
Zebrafish Modeling of PAX3-FOXO1 Driven Rhabdomyosarcoma | University of Texas Southwestern Medical Center / Genevieve Kendall, PhD | Young Investigator Grants | 2015 | Texas |
Genetically Engineered T Cells as Therapy for Pediatric Glioma | Baylor College of Medicine / Giedre Krenciute, PhD | Young Investigator Grants | 2016 | Texas |
Building a Texas-based center for neuroblastoma clinical research. | Baylor College of Medicine / Heidi Russell, MD | Phase I/II Infrastructure Grants | 2006 | Texas |
Immunotherapy for Osteosarcoma and Ewing sarcoma | Baylor College of Medicine / Nabil Ahmed, MD, MSc | Young Investigator Grants | 2007 | Texas |
Mediators of Metastasis in Alveolar Rhabdomyosarcoma. | University of Texas Health Science Center at San Antonio / Koichi Nishijo, MD, PhD | Young Investigator Grants | 2006 | Texas |
Texas Children's Cancer Center Alex's Lemonade Stand Center of Excellence | Baylor College of Medicine / Stacey Berg, MD - Scholars: Holly Lindsay, MD/MS, Sarah Injac, MD | Center of Excellence Grants | 2012 | Texas |
Characterization and Targeting of p53 Ubiquitination in Neuroblastoma. | Baylor College of Medicine / Eveline Barbieri, MD, PhD | Young Investigator Grants | 2008 | Texas |
Structure-guided de novo design of molecules that selectively target EWS-FLI1 | University of Texas Health Science Center at San Antonio / David Libich, PhD | Innovation Grants | 2023 | Texas |
Exploring the Intersection between Childhood Cancer and Birth Defects to Identify Novel Cancer Predisposition Syndromes | Baylor College of Medicine / Philip Lupo, PhD | Epidemiology Grants | 2014 | Texas |
Pediatric Sarcoma, Rhabdomyosarcoma, and Mechanisms of Origin | University of Texas Southwestern Medical Center / Rene Galindo | 'A' Award Grants | 2010 | Texas |
RNA Methylation in Metabolically Disrupted Pediatric Cancers | University of Texas Health Science Center at San Antonio / Patricia Dahia, MD/PhD | Innovation Grants | 2018 | Texas |
Development of New Approaches to Target MAP Kinase Pathway in RAS-driven Rhabdomyosarcoma | University of Texas Health Science Center at San Antonio / Angelina Vaseva, PhD | R Accelerated Award Grants | 2023 | Texas |
High-throughput CAR NKT Library Screen for Improving Neuroblastoma Immunotherapy | Baylor College of Medicine / Xavier Rios, MD/PhD | Young Investigator Grants | 2020 | Texas |
Treatment of high-risk pediatric brain tumors with a CD133-targeted adenovirus in combination with temozolomide | University of Texas M.D. Anderson Cancer Center / Marta Alonso, PhD | Young Investigator Grants | 2008 | Texas |
Genetic Analysis of Pediatric Gliomas | Baylor College of Medicine / Will Parsons, MD, PhD | 'A' Award Grants | 2009 | Texas |
Function and Dependency of NFkB Activity in ZFTA-RELA Fusion Ependymoma | Baylor College of Medicine / Austin Stuckert, MD | Young Investigator Grants | 2021 | Texas |
Validation of microRNAs as valid targets in a pediatric sarcoma | University of Texas Southwestern Medical Center / Mark Hatley | Young Investigator Grants | 2011 | Texas |
Cell Line and Xenograft Repository | Texas Tech University Health Sciences Center / Patrick Reynolds, MD/PhD | Catalyst Grants | 2014 | Texas |
Turning Killers into THINKers: TME Hostility-Impervious NK Cells for Treating Neuroblastoma and Sarcoma | Baylor College of Medicine / Robin Parihar, MD/PhD | 'A' Award Grants | 2021 | Texas |
Interrogating the Enhancer Landscapes of Ependymoma to Inform Novel Therapies | Baylor College of Medicine / Stephen Mack, PhD | Young Investigator Grants | 2016 | Texas |
Targeting PLK1 as a Common Mechanism in Ph-like ALL | University of Texas M.D. Anderson Cancer Center / Joya Chandra, PhD | Reach Grants | 2016 | Texas |
Multispecific T Cells for Adoptive Immunotherapy of Pediatric High Grade Glioma (HGG) | Baylor College of Medicine / Nabil Ahmed, MD, MSc | Innovation Grants | 2013 | Texas |
The Role of MiRNA Impairment in Wilms' Tumor Formation | University of Texas Southwestern Medical Center at Dallas / Kenneth Chen, MD | Young Investigator Grants | 2016 | Texas |
Strategies for Epigenetically Reprogramming Neuroblastoma Cancer Stem Cells | Baylor College of Medicine / Jason Shohet, MD, PhD | Innovation Grants | 2011 | Texas |
Elucidating the Mechanism of ERK Mediated Pathogenesis of LCH | Baylor College of Medicine / Rikhia Chakraborty, PhD | Young Investigator Grants | 2015 | Texas |
Screening for New Rhabdomyosaroma Pathogenesis Genes in a Drosophila Model | University of Texas Southwestern Medical Center / Kathleen Galindo | Young Investigator Grants | 2012 | Texas |
Modeling and Therapeutic Targeting of p21-Activated Kinase Members in High-Risk Rhabdomyosarcoma | Baylor College of Medicine / Jason Yustein, MD/PhD | Innovation Grants | 2018 | Texas |
Fatigue and Carnitine Levels over Eight Cycles of Chemotherapy in Children and Adolescents. | Baylor College of Medicine / Marilyn Hockenberry | Nurse Researcher Grants | 2008 | Texas |
Targeting MYCN-amplified Neuroblastoma Through RORalpha Activation | Baylor College of Medicine / Eveline Barbiere, MD | Innovation Grants | 2016 | Texas |
The Role of Pyruvate Dehydrogenase in Leukemia | University of Texas Southwestern Medical Center at Dallas / Michalis Agathocleous, PhD | 'A' Award Grants | 2018 | Texas |
Energy Balance Strategies for Decreasing Chemotherapy-Induced Cardiotoxicity | University of Texas M.D. Anderson Cancer Center / Eugenie Kleinerman, MD | Innovation Grants | 2018 | Texas |
Combining Oncolytic Vaccinia Virus with GD2.CAR-modified Vaccinia Virus-specific T-cells for the Treatment of Relapsed Neuroblastoma and Sarcoma | Baylor College of Medicine / Cliona Rooney, PhD | Reach Grants | 2013 | Texas |
Immunotherapy of Neuroblastoma with CAR.GD2 NKT Cells | Baylor College of Medicine / Leonid S. Metelitsa, M.D., Ph.D. | Bio-Therapeutic Impact Award | 2014 | Texas |
V alpha-invariant NKT cells as a novel platform for cancer immunotherapy | Baylor College of Medicine / Leonid Metelitsa, MD, PhD | Innovation Grants | 2012 | Texas |
Parallel sequencing to identify the causes of childhood cancer | Baylor College of Medicine / Sharon Plon | Innovation Grants | 2008 | Texas |
Adoptive immunotherapy using clinical-grade T cells. | University of Texas M.D. Anderson Cancer Center / Laurence Cooper, MD, PhD | Innovation Grants | 2007 | Texas |
Parallel sequencing to identify the causes of childhood cancer. | Baylor College of Medicine / Sharon Plon, MD, PhD | Innovation Grants | 2006 | Texas |
Enhancing the Viability, Function, and Safety, of Genetically-Enhanced NK Cells Within the Solid Tumor Microenvironment With IL-15 and a Suicide Gene | Baylor College of Medicine / Robin Parihar, MD, PhD | Young Investigator Grants | 2015 | Texas |
Understanding the Role of a Novel Hereditary Cancer Gene | University of Texas Health Science Center at San Antonio / Patricia Dahia | Innovation Grants | 2010 | Texas |
Understanding factors contributing to retention in care among children with cancer in sub-Saharan Africa | Baylor College of Medicine / Mark Zobeck, MD, PhD | Psychosocial Launch Grant | 2019 | Texas |
Immunotherapy Of Neuroblastoma With Natural Killer T Cells Engineered To Target O-acetyl-GD2 | Baylor College of Medicine / Andras Heczey, MD | Young Investigator Grants | 2014 | Texas |
Center for Pediatric T Cell Therapy (CEPET) | Baylor College of Medicine / Cliona Rooney | Phase I/II Infrastructure Grants | 2010 | Texas |
Dissecting and Targeting the Wnt Signaling Pathway in Metastatic Osteosarcoma | Baylor College of Medicine / Jason T. Yustein, MD, PhD | Young Investigator Grants | 2013 | Texas |
Role of Primary Cilium Signaling and Dynamics in Medulloblastoma Initiation and Progression | University of Texas Southwestern Medical Center / Saikat Mukhopadhyay, MD/PhD | 'A' Award Grants | 2016 | Texas |
Role of H3.3-G34R mutation in pediatric high-grade glioma | University of Texas M.D. Anderson Cancer Center / Jian Hu, PhD | Innovation Grants | 2021 | Texas |
DICER1-Driven Cancers: Models, Mechanisms and Therapies | University of Texas Southwestern Medical Center at Dallas / James Amatruda, MD/PhD | Innovation Grants | 2016 | Texas |
Telomeres and Telomerase in Pediatric Acute Myeloid Leukemia | Baylor College of Medicine / Maria Gramatges | Young Investigator Grants | 2011 | Texas |
Engineering the CAR T Cells to Overcome Tumor Derived Immune-Inhibition in Glioblastoma | Baylor College of Medicine / Meenakshi Hegde, MD | 'A' Award Grants | 2016 | Texas |
In Situ CD19.CAR-T Generation Using TRIDENT System for Pediatric B Cell Malignancies | Baylor College of Medicine / Masataka Suzuki, PhD | Innovation Grants | 2023 | Texas |
Pre-Clinical Testing of T cells Coded with CARs for DIPG | University of Texas / Laurence Cooper, MD, PhD | Innovation Grants | 2013 | Texas |
Synthetic Gene Expression Regulatory Switches (SynGERS) for Improved CAR T Cell Function in Pediatric Solid Tumors | Baylor College of Medicine / Leidy Diana Caraballo Galva, PhD | Young Investigator Grants | 2023 | Texas |
Adoptive Cell Therapy Targeting Antigen Escape Variants in Childhood High Grade Glioma | Baylor College of Medicine / Meenakshi Hegde | Young Investigator Grants | 2012 | Texas |
Immunotherapy for Pediatric Atypical Teratoid/Rhabdoid Tumor | Baylor College of Medicine / William Decker, PhD | Reach Grants | 2013 | Texas |
Synthetic gene expression regulator switches (SynGERS) expressed in CAR T cells to cure children with solid tumors | Baylor College of Medicine / Andras Heczey, MD | R Accelerated Award Grants | 2023 | Texas |
Two-pronged Cell Therapy: Engineering T Cells to Redirect Bystander T- and NK-Cells to Pediatric Cancer | Baylor College of Medicine / Stephen Gottschalk, M.D. | Innovation Grants | 2014 | Texas |
B-lapachone as a Novel Targeted Therapy for ATRTs and other Pediatric Cancers | University of Texas Southwestern Medical Center / James Amatruda, MD, PhD | Reach Grants | 2013 | Texas |
Using Neurofibromatosis-1 (NF1) to understand Pediatric Brain Tumor Initiation | MD Anderson Cancer Center / Yuan Pan, PhD | Young Investigator Grants | 2020 | Texas |
GENOME ORIGAMI: Refolding Aberrant Chromosome 3D Structure for Treating NUT Carcinoma | Baylor College of Medicine / Kyle Eagen, PhD | R Accelerated Award Grants | 2022 | Texas |
The Meaning of Adolescents' Eating Experiences during Bone Marrow Transplant Recovery. | Baylor College of Medicine / Cheryl Rodgers, PhD, RN | Nurse Researcher Grants | 2007 | Texas |
Natural Killer T cells with an IL-15-armored GD2-specific CAR for Children with Neuroblastoma | Baylor College of Medicine / Andras Heczey, MD | Bio-Therapeutic Impact Award | 2017 | Texas |
STAT3 Signaling Profiles Predict Response to Chemotherapy in Pediatric AML | Baylor College of Medicine / Michele Redell, M.D./Ph.D. | Springboard Grants | 2014 | Texas |
A novel compound for treatment of T cell leukemia | Huntsman Cancer Institute / Nikolaus Trede | Innovation Grants | 2010 | Utah |
Targeting Metabolism in Alveolar Soft Part Sarcomagenesis | Huntsman Cancer Institute / Kevin Jones, MD | 'A' Award Grants | 2013 | Utah |
GSTM4, a novel target for treating Ewing sarcoma. | Huntsman Cancer Institute / Wen Luo | Young Investigator Grants | 2009 | Utah |
Molecular diagnostic, prognostic, and therapeutic approaches toward Ewing sarcoma. | Huntsman Cancer Institute / Stephen Lessnick | Innovation Grants | 2009 | Utah |
The TC3 Line, a Zebrafish Model of T-Cell Malignancy | Huntsman Cancer Institute / Nathan Meeker, MD | Young Investigator Grants | 2008 | Utah |
Is SIRT5 a Therapy Target in Acute Lymphoblastic Leukemia? | University of Utah / Michael Deininger, MD/PhD | Innovation Grants | 2018 | Utah |
Comprehensive Analysis of Risk Factors for Pediatric Cancers Using the Utah Population Database | Huntsman Cancer Institute / Joshua Schiffman, MD | Epidemiology Grants | 2012 | Utah |
Comprehensive Analysis of Risk Factors for Pediatric Cancers Using the Utah Population Database | Huntsman Cancer Institute / Joshua Schiffman, MD | Epidemiology Grants | 2010 | Utah |
Identification of predisposition genes for Ewing sarcoma segregating in high-risk pedigrees | Huntsman Cancer Institute / Lisa Cannon-Albright, PhD | Innovation Grants | 2012 | Utah |
Ectopic Neuroligin Signaling in Pediatric Glioblastoma | University of Utah / Alex Shcheglovitov, PhD | Innovation Grants | 2023 | Utah |
Determining Social Risk Factors for Poor Outcomes in Pediatric Cancer Using Children’s Oncology Group Registries | University of Utah / Anne Kirchhoff, PhD/MPH | Epidemiology Grants | 2019 | Utah |
Relationships Between Symptoms and the Hospital Care Environment in Children and Adolescents with Cancer | Huntsman Cancer Institute / Lauri Linder | Nurse Researcher Grants | 2010 | Utah |
LSD1 Inhibition to Treat T-cell Acute Lymphoblastic Leukemia/Lymphoma | University of Virginia, School of Medicine / Michael Engel, MD/PhD | Reach Grants | 2016 | Virginia |
Small Molecule Inhibitors of ERG for Pediatric Leukemia and Sarcoma | University of Virginia, School of Medicine / John Bushweller, PhD | Innovation Grants | 2015 | Virginia |
Pharmacogenomics and Drug Screening Lead to a Novel Targeted Therapy with Potent and Specific Activity Against Mouse Models of MYCN-amplified Neuroblastoma | Virginia Commonwealth University / Anthony Faber, MD & Yael Mosse, MD (CHOP) | Innovation Grants | 2015 | Virginia |
Critical Contributions of CRM1 to Leukemogenesis | University of Vermont / Jessica Linda Heath, MD | Young Investigator Grants | 2015 | Vermont |
TrkB Signaling in the Genesis of Murine Neuroblastoma | University of Vermont / Rae Nishi, PhD | Innovation Grants | 2007 | Vermont |
Developing Targeted Immunotherapy Against Pediatric Acute Myeloid Leukemia | Fred Hutchinson Cancer Research Center / Melinda Biernacki, MD | Young Investigator Grants | 2016 | Washington |
Niche for in Vitro Generation of Hematopoietic Stem Cells from Pluripotent Stem Cells | Fred Hutchinson Cancer Research Center / Brandon Hadland, MD, PhD | Young Investigator Grants | 2014 | Washington |
Improving Development of and Patient Access to Early Phase Pediatric Cancer Clinical Trials | Seattle Children’s Hospital and Regional Medical Center / Russ Geyer | Phase I/II Infrastructure Grants | 2010 | Washington |
Delivering on the Promise of Germline Genetic Testing for RUNX1 Variants | University of Washington, Seattle / Abbye McEwen, MD, PhD | RUNX1 Early Career Investigator Grants | 2022 | Washington |
Targeting Novel Pediatric-Specific FLT3 Mutations | Fred Hutchinson Cancer Research Center / Soheil Meshinchi, MD,PhD | Reach Grants | 2015 | Washington |
Optimizing Bispecific Antibody Therapy for Acute Leukemias | Fred Hutchinson Cancer Research Center / Roland Walter, MD, PhD & James Olson, MD, PhD | Innovation Grants | 2015 | Washington |
Exploiting WT1 Genomic Alterations for Target Identification and MRD Monitoring in Pediatric AML | Fred Hutchinson Cancer Research Center / Phoenix Ho | Young Investigator Grants | 2012 | Washington |
Characterization of Chromatin Landscapes to Identify Therapeutic Vulnerabilities in Diffuse Midline Gliomas. | Fred Hutchinson Cancer Research Center / Jay Sarthy, MD/PhD | Young Investigator Grants | 2019 | Washington |
Advanced Therapeutics for Pediatric Cancer | Seattle Children’s Hospital and Regional Medical Center / Julie Park, MD | Phase I/II Infrastructure Grants | 2008 | Washington |
Establishing the Function of Novel MicroRNAs Associated with Resistance and Relapse in Pediatric AML | Fred Hutchinson Cancer Research Center / Vivian Oehler, MD & Soheil Meshinchi, MD/PhD | Innovation Grants | 2017 | Washington |
Identification of Resistance Mechanisms and Novel Therapeutic Strategies in Tyrosine Kinase Inhibitor Resistant FLT3/ITD Acute Myeloid Leukemia | Fred Hutchinson Cancer Research Center / Katherine Tarlock, MD | Young Investigator Grants | 2014 | Washington |
HA-1 TCR T-cell Immunotherapy for Acute Leukemia | Fred Hutchinson Cancer Research Center / Marie Bleakley, M.D., Ph.D. | Bio-Therapeutic Impact Award | 2014 | Washington |
Novel Antibodies to the C2-set Domain of CD33 for Acute Myeloid Leukemia Immunotherapy | Fred Hutchinson Cancer Research Center / Colin Godwin, MD | Young Investigator Grants | 2018 | Washington |
Serious Morbidity and Financial Outcomes Among Pediatric Cancer Survivors | Fred Hutchinson Cancer Research Center / Beth Mueller, PhD | Epidemiology Grants | 2014 | Washington |
Engineering A Graft Versus Leukemia Effect into Cord Blood Transplant for Acute Lymphoblastic Leukemia | Fred Hutchinson Cancer Research Center / Rebecca Gardner | Young Investigator Grants | 2011 | Washington |
Genomic Alterations in ETV6 Predict Outcome in Pediatric AML | Fred Hutchinson Cancer Research Center / Heather Helton, MD | Young Investigator Grants | 2013 | Washington |
Transcriptome Sequencing (RNA-Seq) for Identification of Novel Markers of Disease Outcome and Therapeutic Targets in Acute Myeloid Leukemia | Fred Hutchinson Cancer Research Center / Fabiana Ostronoff, MD | Young Investigator Grants | 2012 | Washington |
Restoring RUNX1 Levels in FPD/AML | University of Washington, Seattle / Marshall Horwitz, MD/PhD | RARE Grant Program (Research Accelerating RUNX1 Exploration) | 2016 | Washington |
Aberrant DNA methylation in Ewing sarcoma. | Fred Hutchinson Cancer Research Center / Scott Borinstein | Young Investigator Grants | 2009 | Washington |
Use sophisticated approaches to optimize the effectiveness of current chemotherapy agents, and to develop novel chemotherapy agents | Seattle Children’s Hospital and Regional Medical Center / Julie Park, MD | Phase I/II Infrastructure Grants | 2006 | Washington |
Exploiting the Potential of Bromodomain Inhibitors in Ewing Sarcoma | Seattle Children’s Hospital / Shireen Ganapathi, MD | Young Investigator Grants | 2021 | Washington |
Prognostic and Therapeutic Significance of Stem Cell Heterogeneity in AML | Fred Hutchinson Cancer Research Center / Roland Walter, MD, PhD | 'A' Award Grants | 2012 | Washington |
The Role of DNA Methylation in Pediatric Cancer | Fred Hutchinson Cancer Research Center / Scott Diede | Young Investigator Grants | 2010 | Washington |
Self-Management of Cancer-Related Fatigue by Adolescents: Pilot Study of an Evidence Based Educational Resource. | Seattle Children’s Hospital and Regional Medical Center / Catherine Fiona Macpherson | Nurse Researcher Grants | 2008 | Washington |
Immuno-therapeutic Targeting of CD56 in CBA2T3/GLIS2-AML in Children | Fred Hutchinson Cancer Research Center / Soheil Meshinchi, MD/PhD | Reach Grants | 2018 | Washington |
Accelerating Access to Cellular Therapies for the Treatment of Childhood Malignancies | Seattle Children’s Hospital and Regional Medical Center / Julie Park, MD | Phase I/II Infrastructure Grants | 2013 | Washington |
Epigenetic Enhancement of MHCI to Augment Neuroblastoma Immunotherapy | University of Wisconsin - Madison / Paul Sondel, MD, PhD and Amy Erbe-Gurel, PhD | Innovation Grants | 2022 | Wisconsin |
Building Capacity for the Clinical Trials Office at Children's Hospital of Wisconsin - Strengthening Phase I & II Trials Infrastructure | Children’s Hospital of Wisconsin - Milwaukee / Michael J. Burke, MD | Phase I/II Infrastructure Grants | 2015 | Wisconsin |
Development of An Innovative Treatment Strategy for Neuroblastoma and Other Pediatric Tumors: A Novel Phospholipid Ester Analogue and its Multifunctional Cancer-targeting Nanoconstruct | University of Wisconsin - Madison / Mario Otto | Young Investigator Grants | 2012 | Wisconsin |
Role of Kindlin-3 In Natural Killer Cell Mediated Tumor Killing | Children’s Hospital of Wisconsin - Milwaukee / Nathan Schloemer, MD | Young Investigator Grants | 2016 | Wisconsin |
Prospective Symptom Assessment in Children with Advanced Cancer | University of Wisconsin - Madison / Kathleen Montgomery, PhD & Jennifer Madden, RN/MSN | Nurse Researcher Grants | 2015 | Wisconsin |
Phase I Study of Lentivirus Engineered Autologous AML Cells Expressing IL-12 in Children and Young Adults with Relapsed AML | Children’s Hospital of Wisconsin - Milwaukee / Michael Burke, MD & Jeffrey Medin, MD/PhD | Reach Grants | 2017 | Wisconsin |
Molecular Signature of Inflammation | Medical College of Wisconsin / Subramaniam Malarkannan, PhD | Springboard Grants | 2013 | Wisconsin |
Targeting EZHIP as a therapeutic strategy for infantile ependymomas | University of Wisconsin - Madison / Peter Lewis, PhD | Innovation Grants | 2021 | Wisconsin |
Identifying how Pre-existing Anti-Therapeutic Antibodies (PATA) are Associated with Better Outcome in a Clinical Trial of ADCC-inducing Anti-GD2 mAb | University of Wisconsin - Madison / Paul Sondel, MD, PhD | Innovation Grants | 2015 | Wisconsin |
Pediatric Oncology Nurses' Experiences with Prognosis-Related Communication | Marquette University / Amy Newman, RN, MSN | Nurse Researcher Grants | 2014 | Wisconsin |